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Study may help identify unborn children at higher risk for birth defects

Researchers at the University of Toronto have discovered a novel function performed by the breast cancer 1 protein (BRCA1), which regulates DNA repair. Well known for the role it plays in breast and ovarian cancer, this study revealed that the BRCA1 protein actually plays a much broader biological role, particularly in protecting the developing embryo from the damaging effects of reactive oxygen species (ROS).

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

Commonly used fungicides could cause gene expression changes in brain cells

Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions, including Alzheimer's disease and Huntington's disease.

31 Mar 2016

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Researchers at the University of Pittsburgh School of Medicine and Arts & Sciences have designed a more effective version of an FDA-approved epilepsy drug with the potential for fewer side effects, according to a study published on March 22 in Molecular Pharmacology. The experimental agent also could prove to be a treatment for tinnitus and other disorders caused by volatile neural signaling.

31 Mar 2016

Psychedelic compounds could treat patients with mental health issues

Psychedelic compounds have had a colorful past. Although initially investigated for medical uses, they were banned after cultural and political times changed in the 1960s and 1970s. Now, the compounds are getting another chance in the mainstream, according to the cover story of Chemical & Engineering News, the weekly news magazine of the American Chemical Society.

31 Mar 2016

New Rutgers study links protein that helps fight infection to heart and liver disease

A protein that should help fight infection and keep us healthy may be targeted for treating devastating illnesses like heart and liver disease, according to a new Rutgers study.

31 Mar 2016

FDA announces availability of investigational test to screen donated blood for Zika virus

The U.S. Food and Drug Administration today announced the availability of an investigational test to screen blood donations for Zika virus. The screening test may be used under an investigational new drug application (IND) for screening donated blood in areas with active mosquito-borne transmission of Zika virus.

31 Mar 2016

Computer scientists use Big Data to predict life expectancy

Statisticians, computer scientists and medics from the University of East Anglia are launching a new project to predict how long you will live.

31 Mar 2016

Opioids could be dangerous, deadly at high doses

Most people know that heroin is a dangerous drug, but its cousins, the legal, pharmaceutical opioids, such as codeine or hydrocodone, must be safe, right?Not so fast.Opioids—which include the illegal drug heroin as well as prescription medications, including hydrocodone (such as Vicodin), oxycodone (such as OxyContin and Percocet), morphine and codeine—can be dangerous, even deadly, at high doses.

31 Mar 2016

Measuring brain signal variability could help identify patients at higher risk of dementia

Dementia will develop in about 80% of patients with Parkinson's disease, and a new study has found significant variability in brain signaling that could serve as a predictive marker for identifying which patients are at highest risk of dementia.

31 Mar 2016

Fertility 'reassurance' for most chemotherapy-treated female childhood cancer survivors

Both female and male chemotherapy-treated survivors of childhood cancer have an increased risk of impaired fertility, but results suggest that the risk in women is limited to those given specific chemotherapy drugs.

31 Mar 2016

UC Riverside researchers identify immune protein that protects the body from infections

Researchers in the School of Medicine at the University of California, Riverside have identified an immune protein in mice that is quickly triggered in the body following infection and serves to protect the body's tissues. Called "RELMalpha," this protein, whose homologue in humans is called "resistin," is responsible more for protecting the body than attacking the parasite.

30 Mar 2016

Northwestern Medicine study reveals psychotherapy can alleviate genetically depressed rats

Genes are not destiny in determining whether an individual will suffer from depression, reports a new Northwestern Medicine study. Environment is a major factor, and nurture can override nature.

30 Mar 2016

New tool interprets whole-exome tumor sequencing data for better cancer therapies

A University of Colorado Cancer study published today in the Journal of the American Medical Informatics Association describes a new tool that interprets the raw data of whole exome tumor sequencing and then matches the cancer's unique genetics to FDA-approved targeted treatments.

30 Mar 2016

Study finds strong connection between pathological narcissism and sexual assault perpetration

Almost 20 percent of college men have committed some kind of sexual assault, and 4 percent have committed rape, according to a study published by University of Georgia researchers who were examining the link between different kinds of narcissism and the perpetration of sexual assaults.

30 Mar 2016

Researchers develop new technique to study blood vessel inflammation

Nanotechnology has led to better diagnostic techniques and more effective treatments for a variety of illnesses. Tiny devices measuring between 1 and 100 micrometers--one micrometer is equal to one millionth of a meter--enable scientists to observe cell activity and deliver drugs to individual cells--a breakthrough that is on the verge of revolutionizing precision medicine for treatment of diseases such as cancer.

30 Mar 2016

Cairn launches non-invasive Gastric Emptying Breath Test for measuring rate of gastroparesis in adults

Cairn Diagnostics, formerly known as Advanced Breath Diagnostics (ABDiagnostics), has launched the 13C-Spirulina Gastric Emptying Breath Test (GEBT).

30 Mar 2016

Optimized approach for determining prescribed medication associations within pharmacy environment

Researchers at Binghamton University and pharmacy solutions provider Innovation Associates have developed an optimized approach for determining prescribed medication associations within a high-volume pharmacy environment that could save money and time.

30 Mar 2016

Multiple combination therapies could prevent malaria resistance

In order to preserve first-line drugs for treating malaria, multiple combination therapies should be deployed within a population to prevent resistance from developing, according to Maciej Boni from the Centre for Tropical Medicine and Global Health, University of Oxford, UK, and colleagues in a Policy Forum article published in this week's PLOS Medicine.

30 Mar 2016

Versatile Automated Microplate Sample Screening Applications

In this interview, News Medical speaks Tobias Pusterla, Ph.D from BMG Labtech about versatile automated microplate sample screening applications.

From BMG LABTECH GmbH 30 Mar 2016

Drugs News and Research

Study may help identify unborn children at higher risk for birth defects

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

Commonly used fungicides could cause gene expression changes in brain cells

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Psychedelic compounds could treat patients with mental health issues

New Rutgers study links protein that helps fight infection to heart and liver disease

FDA announces availability of investigational test to screen donated blood for Zika virus

Computer scientists use Big Data to predict life expectancy

Opioids could be dangerous, deadly at high doses

Measuring brain signal variability could help identify patients at higher risk of dementia

Fertility 'reassurance' for most chemotherapy-treated female childhood cancer survivors

UC Riverside researchers identify immune protein that protects the body from infections

Northwestern Medicine study reveals psychotherapy can alleviate genetically depressed rats

New tool interprets whole-exome tumor sequencing data for better cancer therapies

Study finds strong connection between pathological narcissism and sexual assault perpetration

Researchers develop new technique to study blood vessel inflammation

Cairn launches non-invasive Gastric Emptying Breath Test for measuring rate of gastroparesis in adults

Optimized approach for determining prescribed medication associations within pharmacy environment

Multiple combination therapies could prevent malaria resistance

Versatile Automated Microplate Sample Screening Applications

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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