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CSHL researchers find way to make immunotherapy effective against colorectal cancer

Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms generally aren't treatable, either through conventional means like chemotherapy or newer immunotherapy drugs.

14 Oct 2026

Investigational knee injection targets cartilage loss in osteoarthritis patients

Keck Medicine of USC has launched a clinical trial testing the safety and tolerability of a new investigational treatment and its potential effects on preventing cartilage deterioration in people with knee osteoarthritis, the most common form of the disease.

14 Oct 2026

Chemists develop blueprint for designing powerful fluorescent materials for better disease detection

Chemists at the University of Bath have discovered how tiny molecular changes can transform the color and brightness of fluorescent probes based on the blue molecule azulene, paving the way for more powerful imaging tools for detecting diseases such as Alzheimer's, Parkinson’s and cancer.

14 Oct 2026

Scientists identify novel autoimmune driver behind DNA repair breakdown in childhood cancer

Researchers have found the first evidence for a previously unsuspected cause of pediatric cancer. They showed that children with such cancers were more likely than their healthy peers to produce ‘auto-antibodies’ targeting six proteins necessary for normal DNA repair. Likewise, they showed that young adults with cancer had greater amounts of these circulating antibodies already years before diagnosis.

14 Oct 2026

New research links postmenopausal ovarian tissue remodeling to elevated cancer vulnerability

In a new, paradigm-shifting study in ovaries from 28 women, scientists at Northwestern University and the Buck Institute for Research on Aging found in the decades well past menopause, the ovary remains biologically active and continues to remodel with age, showing increased inflammation and changes in tissue structure. The study also found a molecular link between ovarian aging and cancer.

14 Oct 2026

From turmeric to fenugreek, scientists examine nature’s potential role in diabetes care

A narrative review examined how curcumin, honey, culinary spices, and traditional remedies may influence oxidative stress, inflammation, mitochondrial function, and insulin signaling in diabetes. Although experimental research and some clinical trials suggest potential metabolic benefits, the authors emphasize that larger, well-controlled studies are needed to establish their effectiveness and safety alongside conventional treatments.

14 Oct 2026

Coffee, citrus and genetics: What scientists found inside human breast milk

In a bioRxiv preprint, researchers analyzed 458 metabolites in breast milk samples from 349 mothers to investigate how maternal diet, genetics, clinical characteristics, and milk-cell gene expression relate to milk composition. Maternal diet explained the greatest share of metabolite variation among the measured maternal factors, while specific genetic variants and gene-expression patterns were associated with individual metabolites, although the study did not establish effects on infant health.

14 Oct 2026

Cigarette smoke exposure alters ovarian and testicular function in mice

New research has shed light on how exposure to cigarette smoke could affect reproductive health in both men and women, identifying changes in biological processes involved in ovarian function and sperm production.

13 Oct 2026

Researchers uncover how metastatic colorectal cancer evades immune attack

Researchers at Hokkaido University, in collaboration with an international team of scientists led by the University of South Florida Health and Tampa General Hospital, have uncovered an important mechanism behind immune evasion in metastatic colorectal cancer (mCRC).

13 Oct 2026

Researchers improve CRISPR technology for detecting HIV and other RNA viruses

Scientists have long used a powerful gene-editing tool called CRISPR to make precise changes to DNA. But a different version of the technology, known as Cas13a, targets RNA, the genetic material found in viruses such as HIV.

13 Oct 2026

CHOP researchers link MAP2K4 variants to a neurodevelopmental disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the mechanisms of previously unknown changes in a gene that result in symptoms associated with a neurodevelopmental disorder.

13 Oct 2026

Scientists studied diet and lung cancer in 95,612 adults. One eating pattern stood out

A prospective study of 95,612 U.S. adults found that those with the highest sulfur microbial diet scores had a 23% higher adjusted lung cancer incidence hazard and a 19% higher lung cancer-related mortality hazard than those with the lowest scores. However, the associations weakened after accounting for overall dietary quality and competing causes of death, and the findings do not establish a causal relationship.

13 Oct 2026

Pancreatic cancer cells continuously reshape DNA to evade treatment

A new analysis of nearly half a million cells from dozens of pancreatic tumors, led by researchers at UC San Diego Moores Cancer Center and New York University (NYU), reveals how pancreatic cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment.

13 Oct 2026

Enhanced CAR T-cell therapy may improve treatment options for patients with B-cell blood cancers

Results from a phase I clinical trial led by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) show a possible way to improve therapy options for patients with relapsed or treatment-resistant B-cell blood cancers.

13 Oct 2026

Scientists find strange bacterial immune system that works backward

Researchers at Gladstone Institutes have uncovered an extraordinarily unusual bacterial immune system that operates in reverse of known defenses.

13 Oct 2026

New AI tool distinguishes Ewing sarcoma with high accuracy

A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically similar tumours with high accuracy.

13 Oct 2026

Childhood leukemia treatment causes rapid, lasting challenges for patient families

New research in the October 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that families of children receiving treatment for B-cell acute lymphoblastic leukemia (B-ALL) experience substantial and lasting challenges beginning early after diagnosis, according to a new multicenter study embedded in a Children's Oncology Group (COG) trial.

13 Oct 2026

Targeting the RUNX1 gene helps reduce severe skin fibrosis

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Cell News and Research

CSHL researchers find way to make immunotherapy effective against colorectal cancer

Investigational knee injection targets cartilage loss in osteoarthritis patients

Chemists develop blueprint for designing powerful fluorescent materials for better disease detection

Scientists identify novel autoimmune driver behind DNA repair breakdown in childhood cancer

New research links postmenopausal ovarian tissue remodeling to elevated cancer vulnerability

From turmeric to fenugreek, scientists examine nature’s potential role in diabetes care

Coffee, citrus and genetics: What scientists found inside human breast milk

Cigarette smoke exposure alters ovarian and testicular function in mice

Researchers uncover how metastatic colorectal cancer evades immune attack

Researchers improve CRISPR technology for detecting HIV and other RNA viruses

CHOP researchers link MAP2K4 variants to a neurodevelopmental disorder

Scientists studied diet and lung cancer in 95,612 adults. One eating pattern stood out

Pancreatic cancer cells continuously reshape DNA to evade treatment

Enhanced CAR T-cell therapy may improve treatment options for patients with B-cell blood cancers

Scientists find strange bacterial immune system that works backward

New AI tool distinguishes Ewing sarcoma with high accuracy

Childhood leukemia treatment causes rapid, lasting challenges for patient families

Targeting the RUNX1 gene helps reduce severe skin fibrosis

Single-cell analysis reveals how pancreatic cancer evades treatment

Switching to a vegan diet rapidly alters liver metabolism

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