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Devastating genetic disease in children may be treatable in adulthood

A devastating genetic disease called CDKL5 deficiency disorder (CDD), which strikes in early childhood, may be significantly treatable even in adulthood, a new study from the Perelman School of Medicine at the University of Pennsylvania suggests.

15 Oct 2021

Mothers pass on the legacy of stress exposure to future generations

A mother's response to stress can even influence her grandchildren. Biologists at the University of Iowa found that roundworm mothers subjected to heat stress passed, under certain conditions and through modifications to their genes, the legacy of that stress exposure not only to their offspring but even to their offspring's children.

13 Oct 2021

Researcher calls for a broader and more inclusive definition of infertility

Academy Research Fellow Jukka Kekäläinen from the University of Eastern Finland calls for a broader and more inclusive definition of infertility in a recent opinion piece published in the journal Human Reproduction last week.

7 Oct 2021

Neonatal outcomes of preterm infants born during COVID lockdowns in Melbourne, Australia

A team of researchers from Australian institutes examined the consequences of community-wide lockdowns on neonatal outcomes of preterm infants, with a secondary focus on the underlying rates of systemic inflammation in infants and mothers around the time of birth.

5 Oct 2021

MR study finds no causal link between age at menarche or age at menopause and Alzheimer's risk

Aging-US published "The role of age at menarche and age at menopause in Alzheimer's disease: evidence from a bidirectional mendelian randomization study" which reported that the association between endogenous estrogen exposure and Alzheimer's disease remains inconclusive in previous observational studies, and few Mendelian randomization studies have focused on their causality thus far.

5 Oct 2021

Yale researchers uncover how the brain takes shape during mid-pregnancy

About four or five months after conception, a burst of synaptic growth begins in the prefrontal cortex (PFC) of the human fetus.

29 Sep 2021

Active management strategy helps women with early, nonviable pregnancies of unknown location

Women with early, nonviable pregnancies of unknown location who were given an active management strategy had more successful pregnancy resolutions than those given an expectant management strategy, according to a recent clinical trial published in JAMA.

13 Sep 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Studies offer insight into how the human body develops and acquires mutations throughout life

New insights into how the human body develops from one cell into trillions, and the genetic mutations that cells pick up along the way, have been generated by two studies from scientists at the Wellcome Sanger Institute, the University of Cambridge and their collaborators.

26 Aug 2021

Frequent adolescent cannabis use may carry intergenerational risks, study finds

Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new University of Bristol-led study.

19 Aug 2021

Study uncovers epigenetic mechanism that mediates a link between fetal conditions and later health

A study at Tampere University has identified one possible epigenetic mechanism through which the conditions at conception may affect the health of an individual in later life.

10 Aug 2021

Why is the South the epicenter of anti-abortion fervor?

Not so long ago, laws governing abortion in Massachusetts and Rhode Island were far more restrictive than those in the Deep South, as state legislators throughout New England regularly banned the procedure, no matter the circumstances, during the 1960s and '70s.

30 Jul 2021

India’s national school feeding program may offer intergenerational nutrition benefits

Women who received free meals in primary school have children with improved linear growth, according to a new study by researchers at the International Food Policy Research Institute.

12 Jul 2021

Study finds minimal SARS-CoV-2 viral load in vaginal secretions

The virus has also been observed to be present in blood, urine, feces, and tears, though not in semen. Vaginal secretions have not been consistently shown to be positive for the virus in most studies. The authors of a new study in the Journal of Clinical Medicine affirm that the presence of the virus in the vagina is rare, irrespective of pregnancy.

28 Jun 2021

Maternal and paternal inflammatory disease can affect pregnancy outcomes

Data presented at the 2021 EULAR congress show women with rheumatoid arthritis (RA) are at increased risks of adverse pregnancy outcomes, especially pre-term birth and babies small for gestational age.

18 Jun 2021

Testing placental hormone levels can help identify candidates for pregnancy complications

Women who will develop potentially life-threatening disorders during pregnancy can be identified early when hormone levels in the placenta are tested, a new study has shown.

8 Jun 2021

Reduced birth rates during early pandemic are predicted to rebound soon

A different type of surge may be on the way more than a year into the pandemic - a baby surge.The COVID-19 shutdown initially seemed to hit pause on pregnancy and birth rates, new research from one major hospital system suggests, but that trend is quickly reversing.

4 Jun 2021

Cmed Technology Adds More Capabilities to its Encapsia Platform and Reports Increased Demand for Use in Decentralized Trials (DCT)

Innovative technology for clinical trials is now, more than ever, necessary to deliver decentralized trials (DCT) and enable design of hybrid protocols that support trial continuity and patient-centricity.

2 Jun 2021

Researchers discover a new and unique form of ALS

In a study of 11 medical-mystery patients, an international team of researchers led by scientists at the National Institutes of Health and the Uniformed Services University discovered a new and unique form of amyotrophic lateral sclerosis (ALS).

31 May 2021

Sperm deliver signals to female reproductive tissues to increase the chances of conception

Sperm are generally viewed as having just one action in reproduction - to fertilize the female's egg - but studies at the University of Adelaide are overturning that view.

18 May 2021