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Andor Neo sCMOS camera is perfect partner for correlative microscopy

CD44 is recognised as an important cell surface receptor involved in the adhesion of circulating leukocytes to endothelium, a process that is critical for their trafficking in the vasculature. Now, a Japanese group of researchers using an ultra-sensitive Andor Neo sCMOS camera in their correlative microscopy set-up has demonstrated that microvilli projections around the cell surface mediate this adhesion.

From Andor Technology Ltd. 11 Mar 2015

TSRI scientists show how to target weak spots of Marburg virus with future treatments

Marburg virus is Ebola's deadly cousin. The virus is up to 90 percent lethal—and doctors are desperate for tools to fight it.

27 Feb 2015

Analytical strategies that support OSD formulation: A new whitepaper from Malvern Instruments

A new whitepaper from Malvern Panalytical provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.

From Malvern Panalytical 12 Feb 2015

Virginia Tech purchases two Bruker fluorescence microscope solutions

The Vutara 350 can break the optical diffraction limit by an order of magnitude, opening up a myriad of research opportunities in single-molecule cellular processes.

From Bruker 11 Feb 2015

Tiny lumps of calcium phosphate may trigger age-related macular degeneration

New research from scientists at the University of Maryland School of Medicine has found that tiny lumps of calcium phosphate may be an important triggering factor for age-related macular degeneration (AMD), a degenerative eye disease that can cause severe vision loss and blindness.

20 Jan 2015

Research findings could lead to new drug design for neurological diseases

A new intermediate step and unexpected enzymatic activity in a metabolic pathway in the body, which could lead to new drug design for psychiatric and neurodegenerative diseases, has been discovered by researchers at Georgia State University.

8 Jan 2015

Eight researchers to receive 2015 Leibniz Prize

The new recipients of Germany's most prestigious research funding prize have been announced. In Bonn today, the Joint Committee of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) decided to award the 2015 Leibniz Prize to eight researchers.

18 Dec 2014

Researchers synthetize molecules to block virus that causes influenza A

The influenza A virus is a contagious and severe respiratory infection that affects animals but also humans. Researchers from the University of Barcelona have synthetized some molecules which are able to block the virus that causes influenza A and some of the mutations that make it resistant to common drugs.

7 Nov 2014

Rockefeller University researchers gain new insight into how cholesterol processes in our body

In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell's membrane, helping to shape the cell and protect it. By mapping the structure of a key enzyme involved in cholesterol production, Rockefeller University researchers and a colleague in Italy have gained new insight into this complex molecular process.

12 Oct 2014

Smart route to confocal Super Resolution microscopy introduced by Olympus

Thanks to a novel software upgrade from Olympus, an optical resolution of up to 120 nm is now achieved in cell and tissue imaging. With the new Olympus FV-OSR software, the FluoView FV1200 is transformed into a powerful system for confocal Super Resolution microscopy.

From Evident Corporation - Life Sciences 3 Oct 2014

$Raloxifene: FDA approved treatment for decreasing fracture risk in osteoporosis$

Raloxifene: FDA approved treatment for decreasing fracture risk in osteoporosis

Raloxifene is a U.S. Food and Drug Administration (FDA)-approved treatment for decreasing fracture risk in osteoporosis.

30 Aug 2014

Researchers at NIH-FEI Living Lab for Structural Biology achieve breakthrough biological results

FEI is pleased to announce that researchers at the NIH-FEI Living Lab for Structural Biology have achieved breakthrough biological results, using FEI’s Titan Krios™ transmission electron microscope (TEM), to elucidate the structural mechanism by which glutamate receptors participate in the transmission of signals between neurons in the brain. Their work is described in Nature, “Structural Mechanism of Glutamate Receptor Activation and Desensitization,” by Meyerson, et al., (DOI: 10.1038/nature13603), http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13603.html .

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Aug 2014

Researchers uncover 3D structure of neuroreceptor

Neurons are the cells of our brain, spinal cord, and overall nervous system. They form complex networks to communicate with each other through electrical signals that are carried by chemicals.

4 Aug 2014

New method allows chemist to use X-rays to look deep into biological samples

It is seldom sufficient to read the declaration of contents if you need to know precisely what substances a product contains.

25 Jul 2014

Researchers prove that CD27 drug is true alternative against malaria

Researchers from the Universitat Politècnica de Catalunya · BarcelonaTech (UPC), the Instituto de Química Mèdica (IQM-CSIC) and the University of Glasgow have proved that the CD27 drug is a true alternative against malaria.

22 Jul 2014

Researchers discover how metal beryllium triggers deadly immune response in the lungs

Using exquisitely detailed maps of molecular shapes and the electrical charges surrounding them, researchers at National Jewish Health have discovered how the metal beryllium triggers a deadly immune response in the lungs.

3 Jul 2014

Progress in constructing protein nanomachines

A route for constructing protein nanomachines engineered for specific applications may be closer to reality.

6 Jun 2014

Shark antibodies reveal evolutionary principles of immunoglobulins

Custom-tailored antibodies are regarded as promising weapons against a multitude of serious illnesses. Since they can accurately recognize specific structures on the surface of viruses, bacteria or cancer cells, they are already being deployed successfully in cancer diagnostics and therapy, as well as against numerous other diseases. The stability of the sensitive antibodies is a decisive factor in every step, from production and storage to therapeutic application.

15 May 2014

Researchers develop first size-based form of chromatography using nanodot technology

Using nanodot technology, Berkeley Lab researchers have demonstrated the first size-based form of chromatography that can be used to study the membranes of living cells.

23 Apr 2014

NeuroPhage engineers series of molecules with potential to treat most neurodegenerative diseases

Researchers from NeuroPhage Pharmaceuticals, Inc. have engineered a series of molecules with the potential to treat most neurodegenerative diseases that are characterized by misfolded proteins, such as Alzheimer's, Parkinson's and Huntington's diseases.