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Insilico Medicine nominates AI-driven drug candidate for cancer, Cushing's syndrome and obesity

The NR3C1 (nuclear receptor subfamily 3 group C member 1) gene encodes the glucocorticoid receptor (GR), a nuclear receptor vital for maintaining physiological homeostasis, and inhibition of NR3C1 could increase the sensitivity of cancer cells to standard chemotherapy, particularly in ovarian cancer.

8 Apr 2026

Climate shock effects persist for generations, fruit fly study shows

A new paper in Molecular Biology and Evolution, published by Oxford University Press, finds that changes in animal development induced by climate shock persist generations after the initial event.

8 Apr 2026

Scientists create large library of mitochondrial DNA mutant models

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

6 Apr 2026

Emerging SARS-CoV-2 variant BA.3.2 shows no signs of greater danger

The Global Virus Network (GVN), representing eminent human and animal virologists from more than 90 Centers of Excellence and Affiliates in over 40 countries dedicated to advancing research, collaboration, and pandemic preparedness, is monitoring the SARS-CoV-2 variant BA.3.2, sometimes informally referred to in media reports as the "cicada" variant, and emphasizes that current evidence does not indicate cause for alarm or heightened public concern.

3 Apr 2026

Lung evolution shaped body size limits in early land vertebrates

The water-to-land transition stands as one of the most significant events in vertebrate evolution, giving rise to the two major groups of living land vertebrates-amniotes and lissamphibians-which occupy markedly different ecological niches.

2 Apr 2026

Innovative technologies transform ocular drug delivery and therapeutic outcomes

Announcing a new article publication in BIO Integration. Ocular drug delivery systems are essential for treating various eye conditions. Ocular conventional drug delivery techniques, such as eye drops (topical administration), often face challenges, like rapid drainage and low bioavailability.

2 Apr 2026

New method improves reliability of protein language model predictions

AI language models, used to generate human-like text to power chatbots and create content, are also revolutionizing biology by treating complex biological data like a language.

1 Apr 2026

AEGIS tool helps scientists study evolution of aging and lifespan

Why do some species live for only weeks while others survive for centuries? Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena have developed AEGIS, a freely available software tool that enables scientists to simulate evolution on a standard computer and investigate how lifespan and aging evolve under different ecological pressures and genetic constraints.

1 Apr 2026

Cholera-causing bacteria and viruses locked in evolutionary arms race

Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study.

1 Apr 2026

"Smart" system distinguishes and neutralizes cancer cells with unprecedented precision

A team from UNIGE has designed a molecular system that distinguishes and neutralizes cancer cells with unprecedented precision, paving the way for autonomous, self-regulating drugs.

1 Apr 2026

Researchers identify the limiting factors behind protein diversification

The number of known proteins is infinitely small in comparison to the universe of possible proteins which could in theory be realized.

31 Mar 2026

Strategic Partnerships at PHARMAP 2026 – Big Pharma’s Shift Toward CDMOs and CMOs

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31 Mar 2026

Broken String Biosciences rebrands to reflect strategic evolution as demand grows for unbiased genome-wide off-target analysis

Broken String Biosciences, a biotechnology company enabling gene editing teams to accelerate development of safer, more effective genetic medicines, today introduced new branding and comprehensive website as part of its strategic repositioning.

From Broken String Biosciences 31 Mar 2026

New AI tool assesses the potential threat posed by new bacteria

Researchers have developed an AI tool that can help determine whether unfamiliar bacteria carry genetic features linked to disease.

27 Mar 2026

Novo Nordisk principal scientist highlights the urgency of advancing human-relevant 3D tissue models ahead of the 11th 3D Tissue Models Summit

As regulatory momentum accelerates globally to reduce reliance on animal testing, leading experts in microphysiological systems (MPS), complex in vitro models (CIVMs), organoids, and organ‑on‑chip technologies are preparing to gather at the 11th 3D Tissue Models Summit, taking place April 28–30, 2026 in Boston.

From Hanson Wade Group - 11th 3D Tissue Models Summit 2026 27 Mar 2026

CDC tracks SARS-CoV-2 BA.3.2 global rise and finds early signals in U.S. wastewater

CDC surveillance shows that the highly divergent SARS-CoV-2 variant BA.3.2 spread to at least 23 countries and was detected in U.S. travelers, patients, airplane wastewater, and wastewater samples across multiple states. The report highlights wastewater and traveler-based genomic surveillance as early warning tools while noting that BA.3.2 has immune-evasion potential but has not rapidly displaced other circulating lineages.

25 Mar 2026

Cancer-fighting antibodies may trigger autoimmune brain disorders

Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated.

25 Mar 2026

Genetic study maps bacteria’s protective armor behind severe infections

The first large-scale genetic study of E. coli's protective armor has identified the five capsule types that are responsible for 70 per cent of all multidrug-resistant bloodstream infections in Europe.

25 Mar 2026

COVID-19 virus evolved quickly but within strict genetic limits

A new paper in Genome Biology and Evolution, published by Oxford University Press, indicates that while the COVID-19 virus has developed rapidly since 2019, it has done so within limited genetic channels.

25 Mar 2026

Deepfake X-rays can deceive radiologists and AI systems

Neither radiologists nor multimodal large language models (LLMs) are able to easily distinguish artificial intelligence (AI)-generated "deepfake" X-ray images from authentic ones, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA).

24 Mar 2026