Genetic News and Research

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Before the first bite: A missing gut protein may set the stage for peanut allergy

For most people, a peanut butter sandwich poses no threat. But for the roughly 1.6 million children in the United States with peanut allergy, exposure can trigger a life-threatening reaction.

6 Oct 2026

Phase III trial tests MRD-guided treatment for patients with ER-positive/HER2-negative breast cancer

Alliance Foundation Trials, LLC (AFT), a national leader in conducting innovative, practice-changing cancer clinical trials, and Natera, Inc., a global leader in cell-free DNA and precision medicine, today announced the launch of AFT-70 NAVIGATE, a randomized phase III trial evaluating a novel molecular residual disease (MRD)-guided treatment strategy for patients with intermediate and high-risk ER-positive/HER2-negative early breast cancer.

5 Oct 2026

New workflow rapidly identifies deadly fungal bloodstream infections

Bloodstream infections are a persistent threat to hospitalized patients, and those caused by fungi are particularly dangerous. Candida species are responsible for most invasive fungal infections worldwide and rank among the leading causes of hospital-acquired bloodstream infections overall.

5 Oct 2026

Enlicitide offers oral treatment option for patients avoiding cholesterol injections

In 2015, a new class of cholesterol-lowering injectable drugs called PCSK9-inhibitors was approved by the Food and Drug Administration (FDA) as a result of clinical research led by UT Southwestern.

5 Oct 2026

Genetic links to ADHD, autism and depression changed with age

The study examines genetic liability for neurodevelopmental disorders, revealing its impact on social functioning and educational attainment across life stages.

5 Oct 2026

Dana-Farber research reveals possible new target for treatment of sickle cell and beta thalassemia

That pathway involves BACH2 and NRF2 and was discovered using a large genome-wide association study that enabled an analysis of genes related to fetal hemoglobin from a wide range of ancestries, including European, African, and Asian ancestries.

5 Oct 2026

Simple urine test can accurately diagnose and track bladder cancer

A simple urine test devised by researchers at Stanford Medicine and the VA Palo Alto Health Care System can diagnose people with bladder cancer more accurately than current standard methods.

5 Oct 2026

Is a high-protein diet hard on your kidneys?

From temporary changes in kidney filtration to the competing nutritional needs of older adults and children, researchers examine when high protein intake may shift from adaptation to concern.

5 Oct 2026

Shift Bioscience publication increases confidence in AI virtual cells for novel target discovery

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to develop new therapies for age driven diseases, today announced the publication of new research in Nature Biotechnology describing an improved calibration framework for deep learning-based genetic perturbation models.

From Shift Bioscience 5 Oct 2026

Ultrasensitive AMH testing offers new insights into midlife ovarian reserve

In women's lifelong health management, the years from 35 to 55 form a critical transition period. During this period, many women face a triple challenge: declining fertility, bothersome perimenopausal symptoms, and delayed or delays in recognizing or confirming menopause.

1 Oct 2026

Sex chromosomes influence immunity, cancer, aging and disease risk

A new review published in Science brings together growing evidence that the X and Y chromosomes do much more than determining biological sex. They also shape how cells function, age and respond to disease.

1 Oct 2026

Phage proteases activate bacterial immune response to viral infection

In the fight to find better treatments for bacterial infections, one rapidly evolving therapy is a group of viruses called bacteriophages (phages). Phages can attack and kill dangerous bacteria while leaving human cells unharmed and bypassing antibiotic resistance.

1 Oct 2026

Loss of tumor suppressor p53 reshapes Wnt signaling to drive mutant cell expansion

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations.

1 Oct 2026

Varying mutation rates in healthy organs explain cancer risk

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

1 Oct 2026

Common gene variant reduces effectiveness of pediatric asthma drug

Children with a variant in the SERPINE1 gene – which is found in 60% of the population – may be less responsive to mepolizumab, a drug used to treat asthma flares, according to a study published in the Journal of Allergy and Clinical Immunology.

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Nuclear enzyme discovery unlocks new paths to combat breast cancer

One of the major challenges in the treatment of the most common subtype of breast cancer (hormone receptor positive, HR+) is the emergence of resistance.

30 Sep 2026

UC San Diego receives funding to establish the Polysubstance Addiction Research Center

Researchers from University of California San Diego have received a $12.6 million award from the National Institute on Drug Abuse (NIDA) to establish the Polysubstance Addiction Research Center (PARC), a multidisciplinary center designed to uncover the biological factors that contribute to addiction across multiple substances.

30 Sep 2026

Scientists discover molecular pathway that controls cellular waste recycling

For years, TFEB has been regarded as one of the most promising therapeutic targets for restoring the cell's ability to clear and recycle waste.

30 Sep 2026

MSU researchers seek to better understand a viral mechanism shared between influenza and HIV

When you get your yearly flu shot, you're helping your body stay one step ahead of the rapidly mutating influenza virus. But what if there was a way to achieve stronger, multi-year protection from a single jab?

30 Sep 2026

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Genetic News and Research

Before the first bite: A missing gut protein may set the stage for peanut allergy

Phase III trial tests MRD-guided treatment for patients with ER-positive/HER2-negative breast cancer

New workflow rapidly identifies deadly fungal bloodstream infections

Enlicitide offers oral treatment option for patients avoiding cholesterol injections

Genetic links to ADHD, autism and depression changed with age

Dana-Farber research reveals possible new target for treatment of sickle cell and beta thalassemia

Simple urine test can accurately diagnose and track bladder cancer

Is a high-protein diet hard on your kidneys?

Shift Bioscience publication increases confidence in AI virtual cells for novel target discovery

Ultrasensitive AMH testing offers new insights into midlife ovarian reserve

Sex chromosomes influence immunity, cancer, aging and disease risk

Phage proteases activate bacterial immune response to viral infection

Loss of tumor suppressor p53 reshapes Wnt signaling to drive mutant cell expansion

Varying mutation rates in healthy organs explain cancer risk

Common gene variant reduces effectiveness of pediatric asthma drug

Esophageal cancer leaves a distinct metabolic signature in the gut

Nuclear enzyme discovery unlocks new paths to combat breast cancer

UC San Diego receives funding to establish the Polysubstance Addiction Research Center

Scientists discover molecular pathway that controls cellular waste recycling

MSU researchers seek to better understand a viral mechanism shared between influenza and HIV

Event guide: 2nd World RNA-Based Therapeutics & Vaccines Summit Korea eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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