Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

Machine learning methods may be effective in screening patients for sleep disorder risk

A machine learning model can effectively predict a patient's risk for a sleep disorder using demographic and lifestyle data, physical exam results and laboratory values, according to a new study published this week in the open-access journal PLOS ONE by Samuel Y. Huang of Virginia Commonwealth University School of Medicine, and Alexander A. Huang of Northwestern Feinberg University School of Medicine, US.

12 Apr 2023

Unexpected discovery could inspire new strategies for preventing liver disease and cancer

Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide.

12 Apr 2023

UC-led research team receives NIH grant to study the role of an enzyme in lysosome function

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes.

11 Apr 2023

Prenatal and early childhood nutritional exposures: a review of the developmental contributions to obesity

Researchers reviewed the latest studies on nutritional exposures during prenatal and early childhood stages.

11 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates -; bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

10 Apr 2023

Alzheimer's risk patients may benefit from Mediterranean keto diet, study shows gut microbiome changes

In a recent study published in the Journal of the Alzheimer's Association (AA), researchers examined the effects of a low-carbohydrate-modified Mediterranean ketogenic diet (MMKD) on the gut microbiome and metabolome of patients at risk for Alzheimer's disease (AD).

9 Apr 2023

ChatGPT can help empower patients and improve health literacy for different populations

A new study by Cedars-Sinai investigators describes how ChatGPT, an artificial intelligence (AI) chatbot, may help improve health outcomes for patients with cirrhosis and liver cancer by providing easy-to-understand information about basic knowledge, lifestyle and treatments for these conditions.

7 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

UCI biologists discover how to ward off harmful effects caused by a high-fat diet

Eating lots of fats increases the risk of metabolic disorders, but the mechanisms behind the problem have not been well understood.

5 Apr 2023

Drug used to treat liver disease may decrease SARS-CoV-2 infections and reduce COVID-19 severity

SARS-CoV-2, the virus that causes COVID-19, attaches to a cellular receptor called angiotensin-converting enzyme 2 (ACE2), and activation of the farnesoid X receptor increases ACE2 expression.

5 Apr 2023

Interplay between Western diet, gut microbiota, and cancer development

In a review article published in the journal Seminars in Immunology, scientists have explored the relationship between the Western diet, gut microbiota, and cancer development.

4 Apr 2023

AI chatbot may help improve health outcomes for patients with cirrhosis and liver cancer

31 Mar 2023

What is the effect of supplementing raisins on improving cognitive performance, cardiovascular risk factors, and markers of inflammation?

Researchers devised a protocol to examine the effect of raisin supplementation on cognitive function in older adults.

31 Mar 2023

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

A study published in the Journal of Nutritional Biochemistry investigated the changes in gene expressions during an overfeeding episode. It demonstrated that supplementation of grape polyphenols in healthy lean men modulates the expression of genes related to adipose tissue angiogenesis.

28 Mar 2023

Beethoven's cause of death revealed through DNA analysis of his hair

In a recent article published in the journal Current Biology, an international team of researchers sequenced the whole genome to high coverage from eight authenticated hair strands from Ludwig van Beethoven, one of the most influential European classical music composers born in 1770. He died on March 27, 1827.

27 Mar 2023

New study investigates effect of short-term PM2.5 exposure on blood lipids

A recent Scientific Reports study sought to address a gap in research and determined the association between short-term PM2.5 exposure and blood lipids.

22 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Gut microbiota-derived biomarkers for identifying patients with fatty liver disease

A recent study at the University of Jyväskylä (Finland) compared the gut microbiota and gut-derived metabolites between healthy controls and individuals with fatty liver.