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New compound advances body clock independent of dosing time

A collaborative team including Emeritus Professor Tei H. (Kanazawa University), Associate Professor Takahata Y. (Osaka University), Professor Numano R. (Toyohashi University of Technology), and Associate Professor Uriu K. (Institute of Science Tokyo) discovered that Mic-628 selectively induces the mammalian clock gene Per1.

4 Feb 2026

Implantable immune scaffold predicts type 1 diabetes weeks before symptoms

The study highlights a presymptomatic phase in type 1 diabetes progression, using immune niches to track immune changes before blood sugar abnormalities.

4 Feb 2026

Early pregnancy reshapes breast aging and lowers cancer risk

A new study by cell biologists at the University of California, Santa Cruz, suggests that an early first pregnancy may protect against breast cancer decades later by preventing age-related changes in breast cells that are linked to tumor formation.

3 Feb 2026

MET signaling plays a critical protective role in acetaminophen-induced acute liver failure

A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF).

2 Feb 2026

New platform improves prediction of human antibody drug responses

An international research consortium, led by scientists at VIB and UGent, has developed a new platform that could change how antibody medicines are tested and brought to patients. The

1 Feb 2026

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature aging and embryonic lethality in mice.

31 Jan 2026

Microneedle patches enhance acne treatment with dual drug delivery

Acne vulgaris affects a large proportion of adolescents and young adults and can lead to long-term scarring and psychological distress.

30 Jan 2026

Study uncovers how the brain's 'memory replay' process is impaired in Alzheimer's disease

Memory dysfunction in Alzheimer's disease may be linked to impairment in how the brain replays our recent experiences while we are resting, according to a new study in mice by University College London (UCL) scientists.

29 Jan 2026

Newly discovered compound can advance the body's internal clock

A Japanese research team has discovered a new compound that can advance the body's internal clock—offering hope for faster recovery from jet lag and better adaptation to night-shift work.

28 Jan 2026

New discovery may aid in early detection of rare genetic disease

Virginia Tech researchers discovered an indication hidden in the brain that may help doctors identify children suffering from a rare genetic disease earlier. Their findings were published recently in EMBO Molecular Medicine.

28 Jan 2026

Immune system dysfunction may fuel progressive heart failure after heart attacks

When the heart's muscle is weakened or injured due to a heart attack, it can make it hard for the heart to pump enough blood to meet the body's needs.

27 Jan 2026

PFOA exposure disrupts hormone signaling and impairs embryo implantation in mice

A new experimental study has found that perfluorooctanoic acid (PFOA), a widely used industrial chemical, can interfere with key biological processes required for successful embryo implantation, raising concerns about its potential impact on female fertility.

27 Jan 2026

New research initiative aims to develop retinal screening tool for Alzheimer's

The human eye may literally become a window revealing the earliest signals of Alzheimer's disease, thanks to a new federally funded research initiative at Oregon Health & Science University.

27 Jan 2026

Scientists offer new insight into how common parasite T. gondii causes disease

A University of California, Riverside team of scientists has found that Toxoplasma gondii, a common parasite affecting up to one-third of the global population, is far more complex than previously believed.

27 Jan 2026

KAIST proposes novel strategy for multifactorial Alzheimer's treatment

Conventional treatments of Alzheimer's disease, one of the most common forms of dementia, have been largely focused on targeting individual pathological features.

27 Jan 2026

WVU researchers explore how to restore vision in people with inherited blindness

A research team at the WVU is studying how to restore vision in people who develop a form of inherited blindness.

26 Jan 2026

Gene therapy targeting connexin 43 shows promise across inherited heart diseases

University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse model can dramatically improve heart function and extend survival in several inherited forms of arrhythmogenic cardiomyopathy (ACM)

26 Jan 2026

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine - which designs nanotechnology-based platforms for clinical translation across specialties - developed a strategy for delivering therapeutic messenger RNA (mRNA) to the inner lining of the uterus (endometrium) in mice via modified lipid nanoparticles (LNPs), which are small capsules made of fatty molecules.

22 Jan 2026

Alterations in liver metabolism experienced by individuals with Down syndrome

Researchers at the University of Colorado Anschutz Linda Crnic Institute for Down Syndrome (Crnic Institute) have uncovered compelling evidence that individuals with Down syndrome experience significant alterations in liver metabolism, including elevated levels of bile acids in the bloodstream and other biomarkers of liver dysfunction.

22 Jan 2026

Methionine: A dietary key to surviving infection

As soon as you are wounded-whether from grabbing a hot pan or contracting the flu-you begin a unique journey through variable symptoms toward either recovery or death.

22 Jan 2026

Mouse Model News and Research

New compound advances body clock independent of dosing time

Implantable immune scaffold predicts type 1 diabetes weeks before symptoms

Early pregnancy reshapes breast aging and lowers cancer risk

MET signaling plays a critical protective role in acetaminophen-induced acute liver failure

New platform improves prediction of human antibody drug responses

Research reveals a link between defective DNA repair and immune-driven inflammatory disease

Microneedle patches enhance acne treatment with dual drug delivery

Study uncovers how the brain's 'memory replay' process is impaired in Alzheimer's disease

Newly discovered compound can advance the body's internal clock

New discovery may aid in early detection of rare genetic disease

Immune system dysfunction may fuel progressive heart failure after heart attacks

PFOA exposure disrupts hormone signaling and impairs embryo implantation in mice

New research initiative aims to develop retinal screening tool for Alzheimer's

Scientists offer new insight into how common parasite T. gondii causes disease

KAIST proposes novel strategy for multifactorial Alzheimer's treatment

WVU researchers explore how to restore vision in people with inherited blindness

Gene therapy targeting connexin 43 shows promise across inherited heart diseases

Targeted uterine mRNA treatment boosts fertility outcomes in mice

Alterations in liver metabolism experienced by individuals with Down syndrome

Methionine: A dietary key to surviving infection

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