B Cell News and Research

RSS

Study uncovers 'cell of origin' of the second most common lung cancer

The 'cell of origin' of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered, in a new study in mice and humans from researchers at UCL, the Wellcome Sanger Institute and the University of Cambridge.

2 May 2025

Gut immune cells linked to worsening rheumatoid arthritis

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

2 May 2025

HHS and NIH announce the development of next-generation, universal vaccine platform

Colorized transmission electron micrograph of influenza A/H1N1 virus particles. The U.S. Department of Health and Human Services (HHS) and the National Institutes for Health (NIH) today announced the development of the next-generation, universal vaccine platform, Generation Gold Standard, using a beta-propiolactone (BPL)-inactivated, whole-virus platform.

1 May 2025

TDP-43 dysfunction in brain blood vessels may drive Alzheimer's and ALS progression

Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein shortage primarily affects the brain's blood vessels.

30 Apr 2025

Existing therapies may help control chronic muscle inflammation in Duchenne muscular dystrophy

A new study led by researchers at Hospital for Special Surgery (HSS) suggests that currently available therapies may help control chronic muscle inflammation in Duchenne muscular dystrophy (DMD), a severe condition that leads to muscle weakness and premature death.

30 Apr 2025

Researchers identify blood biomarkers linked to Long COVID symptoms

Researchers at Karolinska Institutet have identified biomarkers in the blood associated with symptoms of long COVID, particularly severe respiratory disorders.

30 Apr 2025

Clusterin identified as key marker for aging in blood stem cells

In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging.

30 Apr 2025

High fructose diets impair brain function and appetite control, study shows

Review highlights how excessive fructose intake disrupts brain energy balance, appetite regulation, and cognitive function. Processed sources, such as sugary drinks, may overwhelm metabolic pathways and induce neuroinflammation, particularly during adolescence.

30 Apr 2025

NR2F1 promotes cataract formation by activating STAT3 pathway

Cataracts are a prevalent ocular condition characterized by a progressive decline in vision, ultimately leading to blindness.

30 Apr 2025

Machine learning provide new insights into how the brain responds to heroin use

Object recognition software is used by law enforcement to help identify suspects, by self-driving cars to navigate roadways and by many consumers to unlock their cell phones or pay for their morning coffee.

30 Apr 2025

Higher biological age linked to increased dementia risk

People whose biological age is higher than their chronological age may be more likely to develop dementia than people whose biological age matches or is lower than their chronological age, according to a study published on April 30, 2025, online in Neurology, the medical journal of the American Academy of Neurology.

30 Apr 2025

Can folic acid prevent or promote breast cancer? It depends on dose and DNA

Folic acid plays a dual role in breast cancer depending on dose and context. While moderate intake may reduce risk, high levels or genetic variants disrupting metabolism may promote tumor progression via altered DNA methylation.

30 Apr 2025

Rare TYROBP gene variant found in Finns linked to increased Alzheimer's risk

Found in the Finnish population, a rare variant of the TYROBP gene significantly increases the risk of Alzheimer's disease, a new study led by the University of Eastern Finland shows.

30 Apr 2025

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

Researchers explore the medicinal role of curcumin in the treatment and prevention of neuroinflammation and metabolic disorders.

30 Apr 2025

Study links pregnancy specific genes to poorer lung cancer outcomes in women

Lung cancer can co-opt genes that normally help a fetus develop and evade the mother's immune system. And while these pregnancy-specific glycoproteins (PSGs) can get activated in the cancers of both men and women, female patients had poorer outcomes, a Memorial Sloan Kettering Cancer Center (MSK) research team has found.

29 Apr 2025

HonorHealth Research Institute treats first patient in global trial targeting aggressive melanoma

HonorHealth Research Institute recently treated the first patient in a 50-site international clinical trial that will test a new type of therapy aimed at difficult-to-treat melanoma, an aggressive type of skin cancer.

29 Apr 2025

Machine learning uncovers promising drug leads against human enterovirus 71

Artificial intelligence algorithms have now been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.

29 Apr 2025

Nectin4-targeted VHH-CAR-T cells show potency against bladder cancer

Announcing a new article publication for BIO Integration journal. Bladder cancer (BLCA) is one of the most common malignancies and the second most frequent urogenital tract tumor.

29 Apr 2025

Genetic variation found to influence tumor microbiota and colorectal cancer progression

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. While scientists believe that gut microbiota play an important role in both the onset and progression of CRC, emerging evidence points to the significance of intratumoral microbiota-microbiota inside tumors-in CRC progression.

29 Apr 2025

New compounds identified as inhibitors of DNA topoisomerase 1

Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA.

29 Apr 2025