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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

First crystal structure of alternative DNA shape from the insulin gene revealed

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.

9 Sep 2024

Age-related fibroblast changes in males drive aggressive melanoma

Age-related changes in the fibroblasts, cells that create the skin's structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel Cancer Center.

6 Sep 2024

Understanding the cooperation of transcription factors in gene expression

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells.

6 Sep 2024

Individuals with periodontitis exhibit unique inflammatory protein profile in the blood

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden.

6 Sep 2024

Scientists reveal how DNA methylation drives astrocytes to become stem cells, unlocking new potential for brain repair

Researchers have discovered that DNA methylation is crucial for reprogramming astrocytes into stem cells in the adult mouse brain, especially after ischemic injury, with potential implications for regenerative medicine.

6 Sep 2024

Mpox inactivated in 60 seconds with Σ-MM™ & patient friendly collection swab

In the wake of the global Mpox outbreak in non-endemic countries in 2022, the medical community has been searching for safer and more efficient ways to transport and test virus samples, especially from patients in areas with limited biological containment facilities.

From Medical Wire 6 Sep 2024

AI reveals new drug targets for cancers with limited treatment options

Researchers at Weill Cornell Medicine have used artificial intelligence to identify drug targets based on mapping regulatory networks in patient tumors.

5 Sep 2024

Harnessing bacteriophages as targeted treatments for drug-resistant bacteria

As antibiotic resistance becomes an increasingly serious threat to our health, the scientific and medical communities are searching for new medicines to fight infections.

5 Sep 2024

Unraveling psychiatric disorders with cutting-edge epigenetic tools

The "Innovators & Ideas: Rising Star" section of Genomic Psychiatry features an illuminating "Genomic Press Interview" with Dr. Pierre-Eric Lutz, a rising star in the field of neuro-epigenetics.

5 Sep 2024

New technique promises faster DNA analysis in sexual assault cases

A team of researchers has developed a radical new technique for analyzing evidence in sexual assault cases. The new approach could streamline the forensics pipeline and reduce delays in the processing of DNA evidence.

5 Sep 2024

Bats and birds in Madrid are top carriers of zoonotic pathogens, study reveals

Researchers characterize potential zoonotic pathogens present in fecal samples of urban vertebrate species.

4 Sep 2024

Astrocytes reprogrammed to brain stem cells through methylation

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain.

4 Sep 2024

PQBP3 protein found to play key role in aging and brain disorders

In a recent study published online on August 5 2024 in The EMBO Journal, researchers from Tokyo Medical and Dental University (TMDU) in Japan have uncovered a crucial piece of this puzzle by focusing on the role of a single nucleolar protein.

3 Sep 2024

NIH funds study on complex evolutionary adaptation in human DNA

Natural selection is an important evolutionary force that enables humans to adapt to new environments and fight disease-causing pathogens.

3 Sep 2024

Newly discovered antibody can neutralize all known variants of SARS-CoV-2

Researchers have discovered an antibody able to neutralize all known variants of SARS-CoV-2, the virus that causes COVID-19, as well as distantly related SARS-like coronaviruses that infect other animals.

3 Sep 2024

Scientists reveal global catalog of microbial small proteins, unlocking microbiome secrets

Researchers developed a global catalog of nearly one billion small open reading frames (smORFs) from microbial genomes, revealing significant protein diversity, particularly in archaea, and providing new tools for microbiome research.

2 Sep 2024

Clonal hematopoiesis drives femoral atherosclerosis in middle-aged adults

Researchers reveal that clonal hematopoiesis (CH) significantly increases the risk of developing femoral atherosclerosis, suggesting a unidirectional relationship independent of traditional cardiovascular risk factors.

2 Sep 2024

New method revolutionizes DNA-encoded chemical libraries

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies.

2 Sep 2024

Study identifies key predictors of severe mpox cases

The study uncovers factors influencing mpox severity and duration, emphasizing the role of viral load and specific clinical presentations in patient outcomes.

2 Sep 2024

NCCS study uses exosomes to overcome resistance to epidermal growth factor receptor inhibitors

In a new study, clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) have demonstrated the use of exosomes to successfully target squamous cell cancer tumours that are usually resistant to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Their research is the first where exosomes have been applied to target TKI-resistant cancers in Singapore. The findings were published in the journal Developmental Cell last month.

2 Sep 2024