Immune System News and Research

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Oral-gut axis: How mouth bacteria impact your overall health

A recent review in Nature Reviews Microbiology highlights how oral and gut microbiomes interact, impacting overall human health. Oral microorganisms can enter the gut, contributing to dysbiosis and various diseases, necessitating further research on these complex interactions.

24 Jul 2024

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral receptors.

23 Jul 2024

Epigenetic insights into stroke-induced immunological changes

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs - such as the heart.

23 Jul 2024

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control.

23 Jul 2024

Study reveals reduced type 1 diabetes risk in post-10-year-old girls

New research presented at this year's Annual Meeting of the European Association for Study of Diabetes (Madrid, Spain, 9-13 September) shows that the risk of developing type 1 diabetes (T1D) decreases markedly in girls after age 10 years, while the risk in boys stays the same.

22 Jul 2024

USC scientists transform B cells into cancer and HIV destroyers

USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most formidable foes.

22 Jul 2024

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

High mutation count in new COVID-19 variants does not increase immune evasion, study finds

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

19 Jul 2024

Discovery of key RSV immune evasion mechanism offers hope for new treatments

Irish scientists led by a group from Trinity College Dublin have discovered how the dangerous Respiratory Syncytial Virus (RSV) defuses our immune response and, in doing so, they have pinpointed an exciting new target for drug developers.

19 Jul 2024

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against 'inflammaging', which is widely believed to be the root cause of many age-related diseases.

18 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Autoantibodies against type 1 interferons linked to higher susceptibility to viral disease

A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life.

18 Jul 2024

Insights into megakaryopoiesis regulation by plasmacytoid dendritic cells

Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses.

18 Jul 2024

Flu viruses can use a second entry pathway to infect cells

Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers at the University of Zurich have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells.

18 Jul 2024

Cystic fibrosis drug reduces hyper-inflammation in COVID-19 pneumonia patients

A drug commonly used to treat cystic fibrosis improved outcomes for patients with severe COVID-19 pneumonia and could be used to treat other respiratory infections, according to clinical trial results from researchers at UCL, UCLH and the Francis Crick Institute.

18 Jul 2024

Acute gastroenteritis linked to higher rates of irritable bowel syndrome and functional dyspepsia

Researchers examine the prevalence of post-infectious irritable bowel syndrome and post-infectious function dyspepsia following acute gastroenteritis.

18 Jul 2024

Llama-derived molecules target hidden strains of HIV

A research team at Georgia State University has developed tiny, potent molecules that are capable of targeting hidden strains of HIV. The source? Antibody genes from llama DNA.

17 Jul 2024

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

An article published in the journal Cell describes a study that enabled a group of researchers to discover how SARS-CoV-2 evades the cytotoxic immune response by identifying a protein called ORF6 that is a key factor in this mechanism.

16 Jul 2024

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

15 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

Immune System News and Research

Oral-gut axis: How mouth bacteria impact your overall health

More types of lung cells can be infected by SARS-CoV-2 than previously thought, scientists report

Epigenetic insights into stroke-induced immunological changes

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

Study reveals reduced type 1 diabetes risk in post-10-year-old girls

USC scientists transform B cells into cancer and HIV destroyers

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

High mutation count in new COVID-19 variants does not increase immune evasion, study finds

Discovery of key RSV immune evasion mechanism offers hope for new treatments

Novel peptide PEPITEM shows promise in fighting 'inflammaging'

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Autoantibodies against type 1 interferons linked to higher susceptibility to viral disease

Insights into megakaryopoiesis regulation by plasmacytoid dendritic cells

Flu viruses can use a second entry pathway to infect cells

Cystic fibrosis drug reduces hyper-inflammation in COVID-19 pneumonia patients

Acute gastroenteritis linked to higher rates of irritable bowel syndrome and functional dyspepsia

Llama-derived molecules target hidden strains of HIV

Researchers identify ORF6 protein as key to SARS-CoV-2 immune evasion

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

Researchers discover key functions of IRF1 in cancer progression and treatment response

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