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Research focuses on optimization of solid lipid nanoparticle that encapsulates Vinorelbine bitartrate

Vinorelbine Bitartrate, a semi-synthetic vinca alkaloid was approved by the FDA for breast cancer treatment, as it has been proven to be beneficial for first line of defense and subsequent therapies. But its hydrophilic and thermolabile structure causes hindrance to oral clinical translation.

17 Dec 2018

Researchers uncover microRNAs involved in the control of social behavior

The recent discovery of microRNAs as key regulators of biological processes has fueled an explosion of research activity into their function in health and disease.

14 Dec 2018

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells.

14 Dec 2018

Research identifies nerve-signaling pathway behind sustained pain after injury

A toddler puts her hand on a hot stove and swiftly withdraws it. Alas, it's too late--the child's finger has sustained a minor burn. To soothe the pain, she puts the burned finger in her mouth.

13 Dec 2018

Talking about memories enhances the wellbeing of older and younger people

This December, more than one million elderly people will experience loneliness and isolation according to figures by Age UK.

6 Dec 2018

NIH-funded tissue chips that model aspects of the human immune system sent to space

When traveling in space, astronauts experience physiological changes normally associated with aging, such as bone loss, muscle deterioration and altered immune systems. When the astronauts return to Earth, the changes often reverse.

5 Dec 2018

New approach turns B cells into factories that secrete sacs containing microRNAs

Cancer immunotherapy -- efforts to better arm a patient's own immune system to attack tumors -- has shown great potential for treating some cancers. Yet immunotherapy doesn't work for everyone, and some types of treatment can cause serious side effects.

5 Dec 2018

Researcher discovers key differences in protein production between healthy cells and tumors

The human body is made up of more than 200 types of cell, from bone and brain to liver and lung. Each cell type is determined by the particular combination of proteins it produces.

4 Dec 2018

UA researchers discover promising lead in genetic approach to treating deadly brain cancer

Glioblastoma, a deadly brain cancer that has grabbed headlines for claiming the lives of Sens. Edward Kennedy and John McCain, could be "tricked" into sparing more of its victims.

30 Nov 2018

New project launched to map out lung cancer immunology

A 'rule book' to guide precision combination immunotherapies and to speed up the development of new lung cancer treatments will be created as part of a collaboration between Cancer Research UK, the Francis Crick Institute and Bristol-Myers Squibb, announced today (Friday).

29 Nov 2018

Antibiotic could protect against age-related brain diseases

An antibiotic, minocycline, can increase the lifespan of roundworms by preventing the build-up of proteins during aging, a study in the open-access journal eLife reports.

28 Nov 2018

Pitt research team explores whether 'active wrinkles' may help improve synthetic graft design

During a coronary bypass procedure, surgeons redirect blood flow using an autologous bypass graft, most often derived from the patient's own veins. However, in certain situations where the patient does not have a suitable vein, surgeons must rely on synthetic vascular grafts which, while life-saving, are more prone to clot formation that eventually obstructs the graft.

28 Nov 2018

Scientists discover important hallmark of aging in neuronal cells

MIT researchers have discovered that free radicals cause a build-up of short RNA snippets which could contribute to neuronal ageing and cognitive decline.

27 Nov 2018

Research may pave way for development of potent weapons against cancer

Despite significant advances in cancer research, the disease continues to exact a devastating toll. Because cancer is a disease of the body's own cells, which mutate and develop under evolutionary pressure, conventional treatments like chemotherapy and radiation often leave behind a residue of resistant cells that go on to expand and wreak havoc.

27 Nov 2018

CytoReason announces publication of new model for translating data from mouse models to human disease

CytoReason, developer of the world's first machine learning platform for human immune system cell-level simulation, today announces publication of a groundbreaking new model for translating data from mouse models to human disease.

27 Nov 2018

Researchers awarded $7 million funding in Pancreatic Cancer Collective’s 'New Therapies Challenge'

The Pancreatic Cancer Collective, the strategic partnership of the Lustgarten Foundation and Stand Up To Cancer, has awarded a total of $7 million in first-round "New Therapies Challenge" grants to seven teams of top cancer researchers to explore new pancreatic cancer treatments, the American Association for Cancer Research, the Scientific Partner of SU2C, announced today.

21 Nov 2018

Study: Vegetables and salad may include bacteria that are resistant to antibiotics

Salad is popular with people who want to maintain a balanced and healthy diet. Salad varieties are often offered for sale ready-cut and film-packaged. It is known that these types of fresh produce may be contaminated with bacteria that are relevant from the point of view of hygiene.

16 Nov 2018

RetiPharma secures funding to develop new peptide drug for treating degenerative eye disorders

RetiPharma has secured funding from the Novo Nordisk Foundation’s BioInnovation Institute to develop a new drug for degenerative eye disorders.

From Novo Nordisk 15 Nov 2018

Researchers explore role of dietary composition on energy expenditure

The researchers say this effect may improve the success of obesity treatment, especially among people with high insulin secretion (insulin level 30 minutes after consuming a standard amount of glucose).

14 Nov 2018

NIH awards $3.5 million to continue development of robotic system for treating brain tumors

Researchers at Worcester Polytechnic Institute and Albany Medical College, along with corporate partners GE Global Research and Acoustic MedSystems Inc., have received a five-year, $3.5 million award from the National Institutes of Health through the National Cancer Institutes' Academic-Industrial Partnership program, to continue development of an innovative robotic system that, operating within an MRI scanner, can deliver a minimally invasive probe into the brain to destroy metastatic brain tumors with high-intensity therapeutic ultrasound under real-time guidance.

13 Nov 2018

Translation News and Research

Research focuses on optimization of solid lipid nanoparticle that encapsulates Vinorelbine bitartrate

Researchers uncover microRNAs involved in the control of social behavior

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Research identifies nerve-signaling pathway behind sustained pain after injury

Talking about memories enhances the wellbeing of older and younger people

NIH-funded tissue chips that model aspects of the human immune system sent to space

New approach turns B cells into factories that secrete sacs containing microRNAs

Researcher discovers key differences in protein production between healthy cells and tumors

UA researchers discover promising lead in genetic approach to treating deadly brain cancer

New project launched to map out lung cancer immunology

Antibiotic could protect against age-related brain diseases

Pitt research team explores whether 'active wrinkles' may help improve synthetic graft design

Scientists discover important hallmark of aging in neuronal cells

Research may pave way for development of potent weapons against cancer

CytoReason announces publication of new model for translating data from mouse models to human disease

Researchers awarded $7 million funding in Pancreatic Cancer Collective’s 'New Therapies Challenge'

Study: Vegetables and salad may include bacteria that are resistant to antibiotics

RetiPharma secures funding to develop new peptide drug for treating degenerative eye disorders

Researchers explore role of dietary composition on energy expenditure

NIH awards $3.5 million to continue development of robotic system for treating brain tumors

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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