Tumor News and Research

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In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice

In the first experiment of its kind, investigators at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR), based at Stanford University, have shown that single-walled carbon nanotubes (SWCNTs) wrapped in poly(ethylene glycol), or PEG, can successfully target tumors in living animals.

8 Jan 2007

Stem cells grown into brain cells on a new 3D scaffold of tiny protein fragments

An MIT engineer and Italian colleagues will report the invention-which may one day replace the ubiquitous Petri dish for growing cells-in PLoS ONE.

2 Jan 2007

Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA

Researchers from the Swiss Nanoscience Institute in Basel have developed a rapid method to detect the activity of a gene involved in controlling tumor growth.

18 Dec 2006

In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles

In an attempt to determine what factors make one nanoparticle better than another at targeting tumors, a team of investigators in Korea have conducted a systematic tumor-targeting study of a variety of self-assembling nanoparticles.

18 Dec 2006

Dual-mode nanoparticle probes for high-performance magnetic resonance and fluorescence imaging of neuroblastoma

Nanoscale, inorganic fluorescent imaging agents such as quantum dots have become an important tool for researchers studying key biomolecules involved in cancer.

18 Dec 2006

Vascular targeted nanoparticles for imaging and treatment of brain tumors

Combining two promising approaches to diagnosing and treating cancer, a multidisciplinary research team at the University of Michigan has created a targeted multifunctional polymer nanoparticle that successfully images and kills brain tumors in laboratory animals.

4 Dec 2006

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

In attempt to identify biological markers, or biomarkers, that can signal the presence of cancer and help oncologists determine the best course of therapy when cancer is present, teams of investigators are scouring stored tissue samples obtained from thousands of cancer patients.

4 Dec 2006

Computational model for cancer invasion

Vito Quaranta clicks on a small black dot on his computer screen. The dot - which represents about a thousand cancer cells - begins to "grow," morphing into a mass with finger-like projections that looks like an invasive tumor.

2 Dec 2006

Combination therapy shows improvement for breast cancer patients

Giving radiation therapy and chemotherapy at the same time after a lumpectomy helps keep breast cancer from returning locally, according to a study published in the December 1 issue of the International Journal of Radiation Oncology-Biology-Physics, the official journal of ASTRO.

2 Dec 2006

Nanotechnology continues to advance anticancer gene therapy

Given that cancer is a disease in which genetic errors play a major role, it should come as no surprise that many experts envision a time when gene therapy will play an equally important role in the treatment of cancer.

20 Nov 2006

Watching a tumor cell migrate

Using a microfluidics device designed to reproduce the physical microenvironment of small blood vessels and the spaces between cells, researchers at the National University of Singapore have imaged single tumor cells deforming as they migrate through the device.

20 Nov 2006

Risk to childhood cancer survivors for late-occurring strokes

Children who are successfully treated for brain tumors or leukemia are more likely to have strokes later in life, according to new research from UT Southwestern Medical Center.

20 Nov 2006

Gene expression and lung cancer prognosis

While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients.

19 Nov 2006

Evolution is driving therapeutic resistance to cancer therapies

The dynamics of evolution are fully in play within the environment of a tumor, just as they are in forests and meadows, oceans and streams.

19 Nov 2006

Lifestyle decisions that may stave off onset of cancer

Personal choices, such as smoking and consumption of fatty foods, have long been linked to increased cancer risk. During recent years, scientists have been seeking to isolate a variety of lifestyle decisions that may stave off the onset of cancer or even reduce tumor formation in their early stages.

14 Nov 2006

Link between common lifestyle factors, immune system and cancer

The immune system is fickle, and easily influenced by more than just viruses and bacteria. It can be swayed by the seemingly unexpected, such as by what we eat, for example, and affected by surprising sources.

13 Nov 2006

Modified silicon-based surfaces provide good home to proteins

Silicon, whether in its elemental form as silicon wafers or in its oxidized form, known as silicon dioxide or silica, is proving to be a valuable material for biomedical nanotechnology, in large part because of the biocompatibility and chemical inertness of these substances.

13 Nov 2006