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FDA grants Orphan Drug Designation to Ionis Pharmaceuticals' IONIS-HTT Rx for treatment of HD patients

Ionis Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has granted Orphan Drug Designation to IONIS-HTTRx for the treatment of patients with Huntington's disease (HD).

5 Jan 2016

Argon Medical Devices completes acquisition of three vascular products from Rex Medical

Argon Medical Devices, Inc. announced the completed acquisition of three vascular products from Rex Medical, LLC. The OptionELITE Retrievable Vena Cava Filter, CLEANER Rotational Thrombectomy System, and UltraStream Chronic Hemodialysis Catheter are now wholly owned by Argon Medical Devices, Inc.

5 Jan 2016

Study reveals promising mechanism for attacking Ebola virus

In late December, nearly two years after the epidemic began, the World Health Organization has declared the African country of Guinea to be free of Ebola virus infections. But, the race to find a cure and therapies to combat the disease are forging ahead as officials warn that inattention could lead to another epidemic.

5 Jan 2016

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

My laboratory’s long standing interest is the study of the signaling capabilities of stem cells, both under homeostatic conditions

From Beckman Coulter Life Sciences - Flow Cytometry 5 Jan 2016

New phase III trial takes intravaginal DHEA a step closer to approval

A new phase III trial with positive results is taking intravaginal DHEA a step closer to governmental approval. The formulation could provide women who cannot or do not wish to use intravaginal estrogen with an effective vaginal alternative for easing vaginal symptoms and pain with sex after menopause.

5 Jan 2016

EORTC study examines DW-MRI in patients with resectable liver metastases from colorectal cancer

Diffusion weighted (DW) magnetic resonance imaging (MRI) is a widely used technique to detect and characterize cancers as well as to monitor response to therapy. DW-MRI offers numerous advantages for patients with cancer and their treating physicians. It is a non-invasive imaging tool which does not require the administration of contrast agents nor ionizing radiation.

5 Jan 2016

Disease burden, health care costs higher in children with recurrent acute and chronic pancreatitis

The burden of recurrent acute and chronic pancreatitis in children may be higher than previously thought, with high costs related to repeated hospitalizations, report a pair of studies in the Journal of Pediatric Gastroenterology and Nutrition.

5 Jan 2016

$New editorial calls on doctors to individualize treatment decisions based on patients' fracture risk$

New editorial calls on doctors to individualize treatment decisions based on patients' fracture risk

A new editorial published by an International Osteoporosis Foundation Working Group urges physicians to individualize treatment decisions based on their patients' fracture risk, rather than automatically interrupting or stopping bisphosphonate therapy after five or three years.

5 Jan 2016

Hydroxyurea could be a viable option for children with sickle cell disease

A national sickle cell disease study involving Medical University of South Carolina researchers found that for some children with sickle cell disease, the drug hydroxyurea is as effective as blood transfusions to reduce blood flow speeds in the brain. Increased blood flows are a major risk factor for stroke in these children.

5 Jan 2016

Back pain becoming more common in children and adolescents

According to a new literature review in the January issue of the Journal of the American Academy of Orthopaedic Surgeons, it's becoming more common for children and adolescents to seek medical care for back pain. Even with expensive, advanced tests like MRI scans, doctors may not be able to find the exact cause for the pain.

5 Jan 2016

Antiscarring paste can halt fibrosis caused by radiation treatment

An antiscarring paste when applied to the skin of mice halts fibrosis caused by the radiation used in cancer therapy. That is according to a study led by researchers at Laura and Isaac Perlmutter Cancer Center to be published tomorrow in the January edition of the Journal of the Federation of American Societies for Experimental Biology, or FASEB.

5 Jan 2016

African American men with prostate cancer have significantly lower PSA density than Caucasian men

A new study published in The Journal of Urology revealed that African American men with Gleason score 3+3=6 prostate cancer (PCa) produce less prostate specific antigen (PSA) and have significantly lower PSA density (PSAD) than Caucasian men. These findings could have important implications when selecting patients for inclusion in active PCa surveillance programs.

5 Jan 2016

Study: Prostate surgery patients have unrealistic expectations regarding postoperative sexual function

Patients who have undergone radical prostatectomy often have largely unrealistic expectations with regard to their postoperative sexual function, new research shows.

4 Jan 2016

High diversity among circulating tumor cells predicts survival, treatment resistance in prostate cancer patients

Research teams at Memorial Sloan Kettering Cancer Center and Epic Sciences have found that greater diversity among circulating tumor cells (CTCs) in the blood of advanced prostate cancer patients predicts not only shorter overall survival, but also the development of resistance to key anti-androgen therapies.

4 Jan 2016

Numerous experts to attend Global Conference for Collaboration and Development on Regenerative Life Science in Beijing

In order to fulfill the mission of protecting life and health, and to inherit the advanced scientific technologies created by Dr. Rongxiang Xu in his lifetime and his spirit of healing the wounded and rescuing the dying, the Global Conference for Collaboration and Development on Regenerative Life Science cosponsored by The Chinese Red Cross Foundation and Beijing MEBO Institute for Burns, Wounds and Ulcers will be held in the Great Hall of the People in Beijing on Jan. 6, 2016.

4 Jan 2016

UT Southwestern scientists use new gene-editing technique to prevent progression of DMD in young mice

Using a new gene-editing technique, a team of scientists from UT Southwestern Medical Center stopped progression of Duchenne muscular dystrophy (DMD) in young mice.

4 Jan 2016

NCCLC patients with KRAS-related gene mutations may benefit from triple therapy

Although the most common type of lung cancer - non-small cell lung cancer (NSCLC) - has recently seen major treatment advances in some genetic subtypes, other subtypes continue to evade effective treatment. (New therapies exist for NCCLC patients whose cancers harbor mutations in the ALK or EGFR genes, for example.)

4 Jan 2016

Researchers successfully use CRISPR to treat adult mouse model of Duchenne muscular dystrophy

Researchers have used CRISPR to treat an adult mouse model of Duchenne muscular dystrophy. This marks the first time that CRISPR has successfully treated a genetic disease inside a fully developed living mammal with a strategy that has the potential to be translated to human therapy.

4 Jan 2016

MUSC researchers receive $1.68 million NIH grant to study better treatment for chronic pancreatitis, diabetes

MUSC researchers received a $1.68 million National Institutes of Health grant to explore a better treatment for chronic pancreatitis, with the hopes that it also may shed light on a future cure for patients with type 1 diabetes.

4 Jan 2016

Study identifies several risk factors linked to low patient-accrual rates in cancer clinical trials

A new study by researchers at the Hutchinson Institute for Cancer Outcomes Research at Fred Hutchinson Cancer Research Center and the University of Washington has found that 20 percent of cancer clinical trials fail to draw enough participants to render verdicts on experimental therapies.

31 Dec 2015

Therapy News and Research

FDA grants Orphan Drug Designation to Ionis Pharmaceuticals' IONIS-HTT Rx for treatment of HD patients

Argon Medical Devices completes acquisition of three vascular products from Rex Medical

Study reveals promising mechanism for attacking Ebola virus

Using stem cells to tackle CNS disorders: an interview with Dr Stefano Pluchino

New phase III trial takes intravaginal DHEA a step closer to approval

EORTC study examines DW-MRI in patients with resectable liver metastases from colorectal cancer

Disease burden, health care costs higher in children with recurrent acute and chronic pancreatitis

New editorial calls on doctors to individualize treatment decisions based on patients' fracture risk

Hydroxyurea could be a viable option for children with sickle cell disease

Back pain becoming more common in children and adolescents

Antiscarring paste can halt fibrosis caused by radiation treatment

African American men with prostate cancer have significantly lower PSA density than Caucasian men

Study: Prostate surgery patients have unrealistic expectations regarding postoperative sexual function

High diversity among circulating tumor cells predicts survival, treatment resistance in prostate cancer patients

Numerous experts to attend Global Conference for Collaboration and Development on Regenerative Life Science in Beijing

UT Southwestern scientists use new gene-editing technique to prevent progression of DMD in young mice

NCCLC patients with KRAS-related gene mutations may benefit from triple therapy

Researchers successfully use CRISPR to treat adult mouse model of Duchenne muscular dystrophy

MUSC researchers receive $1.68 million NIH grant to study better treatment for chronic pancreatitis, diabetes

Study identifies several risk factors linked to low patient-accrual rates in cancer clinical trials

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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