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Researchers develop multiplexed screening approach to study cancer development in mice

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their cancer-causing roles and determining which combinations of genes cooperate to cause liver cancer.

27 Oct 2015

Scientists decode central signal switch associated with epileptic seizures

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.

27 Oct 2015

Study: Reduction in Amazon deforestation improves air quality, prevents premature deaths

Because of decreasing deforestation and emissions from forest fires in the Amazon over the past ten years, the amount of particulate matter (aerosols), ozone, carbon monoxide, nitrogen oxide and other atmospheric pollutants released by burning biomass has fallen by 30% on average during the dry season in southern Brazil, Paraguay, northern Bolivia and Argentina.

27 Oct 2015

New game-based simulation training for firefighters beats home fires, minimizes heart risk

Firefighting isn't what it used to be. Whether it's a complex blaze raging in an urban high-rise or a seemingly straightforward single-level home fire, modern building construction and furnishings have made fighting fires more difficult: Flames burn hotter, produce more smoke, and spread more quickly.

27 Oct 2015

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Ipsen and the US company EpiVax, Inc. today announced that they have completed a collaborative project that provides a novel approach for creating next generation botulinum neurotoxin (BoNT) and Targeted Secretion Inhibitor (TSI) therapeutics.

27 Oct 2015

Edwards Lifesciences' net sales grow 1.3% to $615.5 million in third quarter 2015

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today reported financial results for the quarter ended September 30, 2015.

27 Oct 2015

CareFusion, AAM Healthcare sign exclusive distribution agreement for APA video laryngoscope

CareFusion, a BD company, today announced its Vital Signs anesthesia delivery and patient monitoring business has entered into an exclusive agreement with AAM Healthcare to distribute its APA video laryngoscope in the U.S. and 12 other countries.

26 Oct 2015

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Mast Therapeutics, Inc., a clinical-stage biopharmaceutical company leveraging its molecular adhesion and sealant technology (MAST) platform to develop novel therapies for sickle cell disease, heart failure, and stroke, announced that it has initiated its Phase 2 study of vepoloxamer for the treatment of patients with chronic heart failure.

26 Oct 2015

Revolutionary prostate biopsy approach more accurate at diagnosing prostate cancer

A revolutionary prostate biopsy approach uses fewer needles and is more accurate for diagnosing prostate cancer. It is done during a real time MRI (magnetic resonance imaging) scan that clearly shows suspicious sites. When done by an expert radiologist using a highly powerful magnet, only a minimum number of needles are used to sample suspicious abnormalities.

26 Oct 2015

SKYSCAN 1275 provides high quality 3D images by highly automated, self optimizing, micro-CT

With the introduction of the new SKYSCAN™ 1275 highly automated, self-optimizing desktop X-ray microtomograph, Bruker puts class-leading imaging into the hands of materials and life scientists in both research and industrial applications, such as high-throughput 3D imaging in quality control and production process monitoring.

From Bruker BioSpin Division 26 Oct 2015

Future Medicinal Chemistry releases themed issue higlighting the Academic Drug Discovery conference

Future Medicinal Chemistry, a leading MEDLINE-indexed journal published by Future Science Group, has released a themed issue dedicated to providing coverage of the presentations that took place at the 2015 Academic Drug Discovery Conference (Cambridge, UK), organized by SelectBio.

26 Oct 2015

Scalable production of gene therapy vectors: an interview with Frank Ubags

Gene therapy involves introducing genetic material into cells to replace missing or malfunctioning genes or to add a gene to express a beneficial protein in order to treat certain diseases, such as cancer or inherited disorders.

26 Oct 2015

Hitachi presents new ultrasound platform at United European Gastroenterology Week

Ultrasound diagnosis is an indispensable tool for a variety of clinical applications and users have high expectations that challenge modern, powerful ultrasound platforms. With the new brand ARIETTA , Hitachi presents a new solution that meets these demands.

26 Oct 2015

KARL STORZ equips new Nuffield Health Cambridge Hospital

KARL STORZ has installed three integrated OR1™ operating theatres in the new and improved £30m Nuffield Health Cambridge Hospital, designed to incorporate the very latest technology and representing a major investment in patient care.

From KARL STORZ 26 Oct 2015

ARN announces availability of comprehensive guide for rehabilitation nursing practice

The Association of Rehabilitation Nurses is pleased to announce the availability of the eagerly awaited The Specialty Practice of Rehabilitation Nursing: A Core Curriculum, 7th Edition. The Core Curriculum serves as the foundation for the rehabilitation nursing profession and can be applied to the many diverse settings and roles, including acute rehabilitation, post-acute care, community settings, skilled nursing homes, case management, research facilities, consulting academia, and clinics.

26 Oct 2015

Novel method for examining small molecules may provide platform for new drug design

Most pharmaceutical drugs consist of tiny molecules, which target a class of proteins found on the surfaces of cell membranes. Studying these subtle interactions is essential for the design of effective drugs, but the task is extremely challenging.

26 Oct 2015

NYSCF conference to focus on translational stem cell and neuroscience research

The New York Stem Cell Foundation 10th Annual Translational Stem Cell Research Conference convenes global leaders in translational stem cell and neuroscience research to present their latest work towards new treatments and cures for the most devastating diseases and injuries currently facing the world.

26 Oct 2015

Pharmaceutical firms need to create more break-out spaces to improve psyche of workforce, says Condeco Software

With most UK adults spending almost an entire day a week online, business leaders in the pharmaceutical industry need to create more break-out spaces in a bid to keep staff invigorated and boost collaboration, according to workplace technology expert Condeco Software.

26 Oct 2015

First computational method based on evolutionary principles developed to predict protein dynamics

Researchers from the Structural Biology Computational Group of the Spanish National Cancer Research Centre, led by Alfonso Valencia, in collaboration with a group headed by Francesco Gervasio at the University College London (UK), have developed the first computational method based on evolutionary principles to predict protein dynamics, which explains the changes in the shape or dimensional structure that they experience in order to interact with other compounds or speed up chemical reactions.

26 Oct 2015

Improved results yielded from new ChIP-seq protocol

Chromatrap®, a business unit of Porvair Sciences, has developed a new protocol that further extends the many advantages of its popular Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits.

From Chromatrap® - Porvair Sciences Ltd 23 Oct 2015

Technology News and Research

Researchers develop multiplexed screening approach to study cancer development in mice

Scientists decode central signal switch associated with epileptic seizures

Study: Reduction in Amazon deforestation improves air quality, prevents premature deaths

New game-based simulation training for firefighters beats home fires, minimizes heart risk

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Edwards Lifesciences' net sales grow 1.3% to $615.5 million in third quarter 2015

CareFusion, AAM Healthcare sign exclusive distribution agreement for APA video laryngoscope

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Revolutionary prostate biopsy approach more accurate at diagnosing prostate cancer

SKYSCAN 1275 provides high quality 3D images by highly automated, self optimizing, micro-CT

Future Medicinal Chemistry releases themed issue higlighting the Academic Drug Discovery conference

Scalable production of gene therapy vectors: an interview with Frank Ubags

Hitachi presents new ultrasound platform at United European Gastroenterology Week

KARL STORZ equips new Nuffield Health Cambridge Hospital

ARN announces availability of comprehensive guide for rehabilitation nursing practice

Novel method for examining small molecules may provide platform for new drug design

NYSCF conference to focus on translational stem cell and neuroscience research

Pharmaceutical firms need to create more break-out spaces to improve psyche of workforce, says Condeco Software

First computational method based on evolutionary principles developed to predict protein dynamics

Improved results yielded from new ChIP-seq protocol

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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