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Denis Mukwege to be honored with 2016 Penn Nursing Renfield Foundation Award for Global Women's Health

Decorated humanitarian and outspoken advocate for women's rights, Dr. Denis Mukwege, will receive the 2016 Penn Nursing Renfield Foundation Award for Global Women's Health for his work in treating and highlighting the plight of women in the war-torn eastern part of the Democratic Republic of the Congo (DRC). The award comes with a $100,000 cash prize. Mukwege will receive the honor during an event at the University of Pennsylvania on March 24, 2016.

29 Oct 2015

New radiotherapeutic bandage shows promise against squamous cell carcinoma in animal model

A radiotherapeutic bandage is being evaluated by researchers for efficacy against squamous cell carcinoma (SCC) in an animal model. These results could confirm the viability of a new and improved strategy for the radiotherapeutic treatment of skin cancer in the clinic. This work is being presented Oct. 28 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

29 Oct 2015

Oncolytic (cancer-killing) viral therapy approved in the U.S. for use against late-stage melanoma

The U.S. Food and Drug Administration announced on Oct. 27 that it has approved, for the first time, an oncolytic (cancer-killing) viral therapy in the United States. The drug was approved for use against late-stage melanoma, a deadly skin cancer that can be difficult to treat.

29 Oct 2015

Yervoy approved for patients at high risk of developing recurrence of melanoma after surgery

Today the U.S. Food and Drug Administration expanded the approved use of Yervoy (ipilimumab) to include a new use as adjuvant therapy for patients with stage III melanoma, to lower the risk that the melanoma will return following surgery.

29 Oct 2015

Cynosure obtains medical device license from Health Canada to market MonaLisa Touch for treatment of GSM symptoms

Cynosure, Inc. today announced that it has received a medical device license issued by Health Canada to market MonaLisa Touch® for the treatment of symptoms related to Genitourinary Syndrome of Menopause (GSM), including vaginal dryness, vaginal burning, vaginal itching, pain, dysuria and dyspareunia.

28 Oct 2015

Study shows restoring testosterone production in men does not impact their fertility

Restoring testosterone production in men may be as effective as replacing it, without compromising their fertility. Two phase III clinical trials show that a drug that restores the body’s natural production of testosterone has no negative effect on a man’s sperm count while a topical testosterone gel causes a significant drop.

28 Oct 2015

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

Researchers studying two generations of a family affected by pediatric acute lymphoblastic leukemia (ALL) have identified an inherited variation in the ETV6 gene that is associated with an increased risk of developing the disease. St. Jude Children's Research Hospital investigators led the study, which appears in the October 28 issue of the journal Lancet Oncology.

28 Oct 2015

New generation of incretin-based medicines allows coordinated action against diabesity

The new generation of incretin-based medicines will allow a coordinated action against the combination diabetes/obesity, also known as diabesity, in some cases with only a single weekly dose, and with the likelihood of additional beneficial effects on other health complications related to this condition, such as cardiovascular and neurodegenerative diseases.

28 Oct 2015

FDA approves Endo’s BELBUCA (buprenorphine) buccal film for use in patients with chronic pain

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc, and BioDelivery Sciences International, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved BELBUCA (buprenorphine) buccal film for use in patients with chronic pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

28 Oct 2015

Hiroshima University researchers report promising new avenue for treating hepatitis B

A promising new avenue for treating hepatitis B has been reported by researchers at Hiroshima University who have developed a new animal model of the disease.

28 Oct 2015

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego. This is the first study in humans to associate opioid blockade with improved survival.

28 Oct 2015

Researchers identify role of cGAS enzyme in autoimmune diseases

Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.

28 Oct 2015

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

The development of a new method to grow three-dimensional organoid cultures of pancreatic tumors directly from patients' surgical tissue offers a promising opportunity for testing targeted therapies and drug responses and personalizing treatments in a rapid, cost-effective manner.

28 Oct 2015

Researchers compare effectiveness of combination therapy for black patients with asthma

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Recent laboratory findings provide novel insight into potential new therapeutic approaches for triple-negative breast cancer, a particularly difficult to treat and aggressive form of the disease.

28 Oct 2015

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. This work is being presented Oct. 27 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

28 Oct 2015

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

Entry of eleven novel therapies expected to drive NSCLC market's growth to $12.7 billion in 2024

Decision Resources Group finds that the entry of eleven novel therapies into the non-small-cell lung cancer (NSCLC) market will drive the market's growth from $5.4 billion in 2014 to $12.7 billion in 2024.

27 Oct 2015

Mylan announces U.S. launch of generic Fusilev for Injection

Mylan N.V. today announced the U.S. launch of Levoleucovorin Calcium Injection 10 mg (base)/mL; 175 mg (base)/17.5 mL and 250 mg (base)/25 mL Single-use Vials, which is the generic version of Spectrum Pharmaceuticals' Fusilev for Injection.

27 Oct 2015

ISIBELa joint research project aims to improve cancer therapy

Some individuals experience cancer recurrence when they enter adolescence or adulthood after they have been successfully treated for cancer in childhood while others don't. But why is this? This is the core question being considered in a research project directed by the University Medical Center of Johannes Gutenberg University Mainz.

27 Oct 2015

Therapy News and Research

Denis Mukwege to be honored with 2016 Penn Nursing Renfield Foundation Award for Global Women's Health

New radiotherapeutic bandage shows promise against squamous cell carcinoma in animal model

Oncolytic (cancer-killing) viral therapy approved in the U.S. for use against late-stage melanoma

Yervoy approved for patients at high risk of developing recurrence of melanoma after surgery

Cynosure obtains medical device license from Health Canada to market MonaLisa Touch for treatment of GSM symptoms

Study shows restoring testosterone production in men does not impact their fertility

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

New generation of incretin-based medicines allows coordinated action against diabesity

FDA approves Endo’s BELBUCA (buprenorphine) buccal film for use in patients with chronic pain

Hiroshima University researchers report promising new avenue for treating hepatitis B

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Researchers identify role of cGAS enzyme in autoimmune diseases

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

Researchers compare effectiveness of combination therapy for black patients with asthma

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

Entry of eleven novel therapies expected to drive NSCLC market's growth to $12.7 billion in 2024

Mylan announces U.S. launch of generic Fusilev for Injection

ISIBELa joint research project aims to improve cancer therapy

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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