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Structural alterations in breast stromal and epithelial DNA

Researchers have uncovered a pattern of DNA damage in connective tissues in the human breast that could shed light on the early stages of breast cancer.

3 Aug 2006

Variation in the CHEK2 gene may triple a woman's risk of developing breast cancer

Study shows that women in the general population who carry a specific CHEK2 mutation are three times as likely as women without the mutation to develop breast cancer.

2 Aug 2006

Uterine cancer may be clue to Lynch syndrome

A new study suggests that women with endometrial cancer should be screened for inherited mutations that could lead to a high risk of several other cancers.

2 Aug 2006

Response to transarterial chemoembolization as a biological selection criterion for liver transplantation in hepatocellular carcinoma

The results of this study appear in the August 2006 issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS).

2 Aug 2006

Researchers determine why gene therapy treatment caused leukemia in some X-linked severe combined immunodeficiency patients

Scientists at St. Jude Children's Research Hospital have developed a mouse model of a severe disease of the immune system that helps explain why gene therapy used to treat children with this disease at an institution in Europe caused some of them to develop leukemia.

2 Aug 2006

Cell walls - an essential building block

Cancer cells, like houses, need building materials for their walls. And as with a house, the cell wall needs to be built at just the right moment to protect and allow the construction of internal components.

2 Aug 2006

Altering fatty acid levels in diet may reduce prostate cancer growth rate

UCLA researchers found that altering the fatty acid ratio found in the typical Western diet to include more omega-3 fatty acids and decrease the amount of omega-6 fatty acids may reduce prostate cancer tumor growth rates and PSA levels.

2 Aug 2006

Do close surgical margins predict if breast cancer will return?

Cancer cells present after additional surgery for breast cancer may predict whether a woman will see her cancer return.

1 Aug 2006

Heat treatment may zap cancer cells

Scientists believe they have discovered a clue as to why so many men with testicular cancer survive against the odds.

26 Jul 2006

Heat sensitivity may make testicular cancer cells more susceptible to standard treatments and die off more readily

Experts at Johns Hopkins have linked scientific evidence spanning more than 30 years to suggest an explanation for why testicular cancer patients like seven-time Tour de France winner Lance Armstrong survive far better than patients with other advanced cancers.

26 Jul 2006

Disease-specific gene expression profiles in patients with rheumatoid arthritis

They sleep together, eat together, and most people find it impossible to tell them apart. Identical twins who grow up together share just about everything, including their genes.

26 Jul 2006

How does the immune system isolate and destroy intruders?

Dendritic cells are the body's "watchdogs". They recognize and then degrade pathogens, isolating characteristic fragments that are recognized by the immune system thus triggering targeted responses.

25 Jul 2006

Gas bubbles used to block oxygen flow to tumors and deliver drugs

The process of blocking blood flow to a tumor is called embolization, and using gas bubbles is a new technique in embolotherapy.

25 Jul 2006

Belfer Foundation funds new translational cancer institute

The Arthur and Rochelle Belfer Foundation has pledged $8 million to create the Arthur and Rochelle Belfer Institute of Hematology and Medical Oncology at Weill Medical College of Cornell University.

25 Jul 2006

Birch bark compound may be potent prostate cancer fighter

A compound found in the bark of the white birch tree - betulonic acid, a derivative of betulinol - may finally have been rendered a water-soluble, bio-available drug, and is already showing the potential to be a possible agent against prostate cancer - in cell culture and in an animal model.

25 Jul 2006