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New study from TSRI and Salk points to cause of debilitating nerve disease

Scientists at The Scripps Research Institute (TSRI) and the Salk Institute for Biological Studies have discovered how a mutant protein triggers nerve damage in a subtype of Charcot-Marie-Tooth (CMT) diseases, a group of currently untreatable conditions that cause loss of function in a person’s hands and feet.

22 Oct 2015

Restoring memory in aging mice

A new study, led by scientists at The Scripps Research Institute (TSRI), the Veterans Affairs San Diego Healthcare System (VA) and University of California (UC) San Diego School of Medicine shows that increasing a crucial cholesterol-binding membrane protein in nerve cells (neurons) within the brain can improve learning and memory in aged mice.

22 Oct 2015

Coagadex now approved by FDA for patients with hereditary Factor X deficiency

The U.S. Food and Drug Administration today approved Coagadex, Coagulation Factor X (Human), for hereditary Factor X (10) deficiency. Until today's orphan drug approval, no specific coagulation factor replacement therapy was available for patients with hereditary Factor X deficiency.

21 Oct 2015

The American Heart Association and Heart Rhythm Society Unite to Improve Cardiovascular Research, Care

The American Heart Association and Heart Rhythm Society today announced a collaboration designed to advance research and improve the delivery of care for people with an irregular heartbeat known as atrial fibrillation (AFib).

20 Oct 2015

Study explores relative role of traumatization, PTSD on sexual behavior and well-being

Among 96 former Swiss indentured child laborers, 22 individuals showed post-traumatic stress disorder (PTSD) symptoms and 53 reported having experienced childhood trauma. Men reported a significantly higher prevalence of both sexual concerns and dysfunctional sexual behavior compared with women.

20 Oct 2015

TSRI researchers find way to change leukemia cells into leukemia-killing immune cells

Scientists at The Scripps Research Institute have found a way to change leukemia cells into leukemia-killing immune cells. The surprise finding could lead to a powerful new therapy for leukemia and possibly other cancers.

20 Oct 2015

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

Takeda Pharmaceuticals, U.S.A., Inc., today announced that data highlighting the efficacy and safety of vedolizumab for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD), will be presented during the 2015 American College of Gastroenterology Annual Scientific Meeting in Honolulu, Hawaii, held on October 16-21.

20 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

APBI brachytherapy improves overall survival in selected patients with early stage breast cancer

The Groupe Européen de Curiethérapie European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) today announced results from a prospective, randomized, multicenter phase III study comparing accelerated partial breast irradiation (APBI) with interstitial multicatheter brachytherapy to whole breast irradiation (WBI).

20 Oct 2015

Diabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of Polyphotonix

In the UK there are currently over 3.5 million people who have diabetes, with a growth rate exceeding 280,000 people per year. Diabetic retinopathy is the most common complication of diabetes.

19 Oct 2015

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

Lexicon Pharmaceuticals, Inc.'s telotristat etiprate, the first oral therapy in development for the treatment of carcinoid syndrome (CS), was associated with patient-reported improvements in social and physical function and emotional well-being according to new exit interview data from the Phase 3 TELESTAR study presented at the 2015 Neuroendocrine Tumor Society Annual Symposium in Austin, Texas.

19 Oct 2015

LEO Pharma's Enstilar gets FDA approval for topical treatment of plaque psoriasis

LEO Pharma Inc., a wholly owned U.S. subsidiary of LEO Pharma A/S, announced today that Enstilar has been approved by the U.S. Food and Drug Administration for the topical treatment of plaque psoriasis in adults 18 years of age and older.

19 Oct 2015

DelMar reports positive data from preclinical study of VAL-083 for treatment of ovarian cancer

DelMar Pharmaceuticals, Inc., a biopharmaceutical company focused on the development and commercialization of new cancer therapies, announced that yesterday it presented positive preclinical data demonstrating the promising potential of its lead product candidate VAL-083 (dianhydrogalactitol) as a treatment for ovarian cancer.

19 Oct 2015

Premature babies face increased risk of mental illness due to weakened connections in brain networks

Babies born prematurely face an increased risk of neurological and psychiatric problems that may be due to weakened connections in brain networks linked to attention, communication and the processing of emotions, new research shows.

19 Oct 2015

NCCN reveals new value initiative for CML and Multiple Myeloma

The National Comprehensive Cancer Network, a not-for-profit alliance of 26 of the world's leading cancer centers, today unveiled its new value initiative—the NCCN Evidence Blocks, published within new versions of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Chronic Myelogenous Leukemia (CML) and Multiple Myeloma.

19 Oct 2015

Immatics, UTHealth to partner on cellular manufacturing for adoptive cellular therapy clinical trials

Immatics US, Inc., a subsidiary of Immatics Biotechnologies GmbH, and The University of Texas Health Science Center at Houston will collaborate on cellular manufacturing for adoptive cellular therapy (ACT) clinical trials.

19 Oct 2015

Rutgers School of Nursing takes lead in $6 million nationwide effort to prevent new HIV infections

Rutgers School of Nursing is taking the lead in a $6 million nationwide effort to greatly reduce new HIV infections - a battle complicated by both the aging of career HIV health care professionals and a failure to engage all people living with HIV into treatment.

19 Oct 2015

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

Identifying a patient's genetic mutation led University of Arkansas for Medical Sciences (UAMS) physician-researcher Ling Gao, M.D., Ph.D., to an existing drug that eliminated the patient's stage IV Merkel-cell carcinoma. Gao's findings, made in collaboration with two other UAMS researchers, were published today in The New England Journal of Medicine.

19 Oct 2015

Baylor study identifies biomarker that could help determine treatment strategies for colorectal cancer patients

Researchers at Baylor Research Institute have identified a small RNA molecule that appears to enable certain colorectal cancers to become especially aggressive, resistant to treatment and likely to migrate and invade normal tissue.

19 Oct 2015

New study provides first clinical evidence on the serious toll human trafficking has on mental health

A new study by researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London provides the first clinical evidence on the toll human trafficking has on mental health, including high levels of post-traumatic stress disorder (PTSD) and depression, amongst a patient population in South London.

19 Oct 2015

Therapy News and Research

New study from TSRI and Salk points to cause of debilitating nerve disease

Restoring memory in aging mice

Coagadex now approved by FDA for patients with hereditary Factor X deficiency

The American Heart Association and Heart Rhythm Society Unite to Improve Cardiovascular Research, Care

Study explores relative role of traumatization, PTSD on sexual behavior and well-being

TSRI researchers find way to change leukemia cells into leukemia-killing immune cells

Takeda highlights safety, efficacy of vedolizumab for UC and CD at ACG Annual Scientific Meeting

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

APBI brachytherapy improves overall survival in selected patients with early stage breast cancer

Diabetic retinopathy therapy innovations: an interview with Richard Kirk, CEO of Polyphotonix

Lexicon's telotristat etiprate improves social and physical function, emotional well-being in cancer patients

LEO Pharma's Enstilar gets FDA approval for topical treatment of plaque psoriasis

DelMar reports positive data from preclinical study of VAL-083 for treatment of ovarian cancer

Premature babies face increased risk of mental illness due to weakened connections in brain networks

NCCN reveals new value initiative for CML and Multiple Myeloma

Immatics, UTHealth to partner on cellular manufacturing for adoptive cellular therapy clinical trials

Rutgers School of Nursing takes lead in $6 million nationwide effort to prevent new HIV infections

UAMS researchers report positive results from treating Metastatic Merkel-cell carcinoma with idelalisib drug

Baylor study identifies biomarker that could help determine treatment strategies for colorectal cancer patients

New study provides first clinical evidence on the serious toll human trafficking has on mental health

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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