Immune System News and Research

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A possible H5N1 vaccine

A vaccine against the most common and deadliest strain of avian flu, H5N1, has been engineered and tested by researchers at the University of Pittsburgh's Center for Vaccine Research and Novavax Inc.

4 Feb 2008

Enzyme released by mast cells in the lungs could be a new target for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma pointing to a potential new target for treatment against the illness.

4 Feb 2008

Zinc may offer protection against cadmium exposure

Cadmium exposure is a known risk factor for prostate cancer, and a new University of Rochester study suggests that zinc may offer protection against cadmium.

4 Feb 2008

Researchers seek trial participants for experimental HIV vaccine called PENNVAX-B

University of Pennsylvania School of Medicine researchers are recruiting healthy, HIV-negative adults to participate in a phase I clinical trial of an experimental HIV vaccine called PENNVAX-B, a DNA-based vaccine which is made using synthetic DNA-based HIV genes.

4 Feb 2008

Advances in age-related macular degeneration treatment

A new study of age-related macular degeneration (AMD), a disease that affects more than nine million Americans, will pave the way for the biopharmaceutical industry to develop better treatments and cures, according to the Foundation Fighting Blindness, which partially funded the research.

4 Feb 2008

Study looks at safe dosages of the isotope astatine-211 for brain tumors

In a study to determine safe dosages of the isotope astatine-211 for patients with recurring brain tumors, researchers were pleasantly surprised to find that not only was the isotope's potency sufficient to kill residual cancer cells without damaging sensitive healthy brain cells, but the patients experienced longer survival rates.

4 Feb 2008

Virtual human in HIV drug simulation

The combined supercomputing power of the UK and US 'national grids' has enabled UCL (University College London) scientists to simulate the efficacy of an HIV drug in blocking a key protein used by the lethal virus.

31 Jan 2008

Stem cell therapy studies for stroke, cerebral palsy prepare for clinical trials

Finding answers about optimal dosage and timing for stem cell therapy in adults with strokes and newborns with ischemic injuries is a goal of two new federally funded studies.

31 Jan 2008

Lungs' mast cells could provide new treatment target for asthma, other respiratory disease

30 Jan 2008

Breakdown of kidney's self-cleaning ability makes them more vulnerable to dysfunction and disease

The kidney actively cleans its most selective filter to keep it from clogging with blood proteins, scientists from Washington University School of Medicine in St. Louis reveal in a new study.

30 Jan 2008

New target found for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

29 Jan 2008

Oseltamivir resistance in European Influenza viruses

Preliminary surveillance into antiviral drug susceptibility against seasonal flu viruses currently circulating in Europe has revealed that some of the A (H1N1) viruses (13%) have shown resistance to the antiviral drug, oseltamivir.

29 Jan 2008

Weakness found in anthrax bacterium

MIT and New York University researchers have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics.

25 Jan 2008

Deficient regulators in the immune system responsible for type 1 diabetes

The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases.

25 Jan 2008

Deficient regulators in the immune system responsible for type 1 diabetes

The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases.

25 Jan 2008

Stanford study finds transplant patient thrives 2 years after stopping immunosuppressive drugs

Luck smiled on Larry Kowalski when his brother agreed to donate a kidney Kowalski needed to live.

24 Jan 2008

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

After a transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can have serious side effects, including infections, heart disease and cancer.

24 Jan 2008

Experimental procedure induces tolerance to mismatched kidney transplants

Four of five patients participating in a trial of an experimental protocol designed to induce immune tolerance to HLA-mismatched kidney transplants have been able to discontinue immunosuppressive drugs.

24 Jan 2008

Evolutionary phenomenon in mice may explain human infertility

Scientists at the University of Liverpool have found that field mice have evolved a unique way of ensuring faster fertilisation, a phenomenon which could explain some cases of infertility in humans.

24 Jan 2008

Candidate malaria vaccine shows promise

A small clinical trial conducted by an international team of researchers in Mali has found that a candidate malaria vaccine was safe and elicited strong immune responses in the 40 Malian adults who received it.

24 Jan 2008