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New Hybrid virus may aid treatment of cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have created a new class of hybrid virus and demonstrated its ability to find, highlight, and deliver genes to tumors in mice.

26 Apr 2006

Cause and treatment for aggressive head and neck cancer may have been found

Researchers report that they have found a potential molecular cause for the aggressive growth and spread of human head and neck squamous cell carcinoma, a highly malignant form of cancer with a very high death rate.

26 Apr 2006

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

The discovery of a gene, called PRDM1, as a tumor suppressor sheds new light on the cause - and possible treatment - of diffuse large B-cell lymphomas (DLBCLs), a cancer of the blood's B-lymphocytes. DLBCLs comprise about 30 percent of non-Hodgkin's lymphomas.

25 Apr 2006

Rare abdominal cancer diagnosis being looked at in a different manner

Their experience treating a rare type of abdominal cancer has helped physicians at Wake Forest University Baptist Medical Center make a new discovery that may change the way it is diagnosed.

24 Apr 2006

Non-Smokers with lung cancer respond better to treatment than smokers

Smoking history contributes to poor outcomes in the treatment of lung cancer, according to a new study. Non-small cell lung cancer (NSCLC) lung cancer patients who have never smoked before in their life have better overall survival rates and respond better to chemotherapy than current or former smokers.

24 Apr 2006

Scientists clarify role of phosphatase and tensin homolog tumor suppressor gene

Jiwang Zhang, Ph.D., formerly a Senior Research Associate at the Stowers Institute for Medical Research, and Linheng Li, Ph.D., Associate Investigator, are credited as the first and last authors, respectively, on a paper highlighting several previously unknown functions of phosphatase and tensin homolog (PTEN), an important tumor suppressor gene.

23 Apr 2006

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia

New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report.

23 Apr 2006

Children with bone cancer in their arms or legs survival rate improved

Ross Wilkins and Stephen Withrow are doctors working together in the fight against bone cancer. Their goals are the same. Their patients are not.

20 Apr 2006

St. Jude develop strategy to speed future development of more effective and less toxic treatments for medulloblastoma

Investigators at St. Jude Children’s Research Hospital have developed a strategy to speed future development of more effective and less toxic treatments for medulloblastoma, a type of brain cancer. Medulloblastomas arise in the back of the brain and account for about 20 percent of childhood brain tumors.

18 Apr 2006

miR 155 overexpression can lead to cancer

Scientists in the Ohio State University Comprehensive Cancer Center say that just one, single, malfunctioning microRNA is sufficient to cause cancer in mice.

18 Apr 2006

Genetic switch that links animal growth and cancer

Laboratory discoveries by scientists at two universities may lead to new directions in cancer therapy drugs. The researchers have discovered that a genetic switch involved in growth and development of an animal is the same one used to prevent normal cells from becoming cancerous.

18 Apr 2006

Significant differences in the patterns of mammography by race and ethnicity

Inadequate use of screening mammography may be an important reason that African-American women are more likely to be diagnosed with advanced stage breast cancer than members of other ethnic groups, according to a new study led by a University of California, San Francisco imaging specialist.

18 Apr 2006

217 new targets for anti-cancer drugs

By identifying novel genes critical to cancer progression, biologists at the U.S. Department of Energy's Argonne National Laboratory have expanded the number of drug targets researchers have available for study to find ways to stop tumors in their tracks.

18 Apr 2006

Laparoscopic partial nephrectomy for centrally located renal tumors

The Cleveland Clinic Group has shown that with experience they have been able to effectively offer laparoscopic partial nephrectomy (LPN) to more patients with centrally located lesions.

17 Apr 2006

Single-dose Carboplatin comparable to prophylactic radiotherapy for stage I seminoma

The risk of relapse for patients with stage I seminoma has traditionally ranged between 10 and 15%, depending on the local pathological characteristics of the tumor.

17 Apr 2006

New method to estimate cancer survival

Cancer survival estimates are important to patients, physicians, clinical trials planning and resource allocation. Predictions by present statistical methods tend to lag behind current outcomes.

17 Apr 2006

Ingredient in red chili pepper has cancer-fighting properties

The study found that capsaicin, the "hot" ingredient in red chili pepper, caused pancreatic cancer cells to die through a process called apoptosis.

13 Apr 2006

Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy

Ultrasound provides a safe and accurate method of detecting breast cancers in pregnant women, as well as assessing response to chemotherapy, according to a study appearing in the April issue of Radiology.

13 Apr 2006

A hormone receptor with regulatory roles in food intake, fear response, and cardiovascular function may also be involved in breast cancer

The UC research team, led by Hassane Amlal, PhD, and Sulaiman Sheriff, PhD, report their laboratory findings on the hormone, neuropeptide Y, and its receptor in the April edition of the journal Cancer Research.

13 Apr 2006

New risks identified after early breast cancer

A new study of women with early stage, localized breast cancer identifies new patterns and risk factors for invasive disease that may influence how patients are treated.

13 Apr 2006