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Vaccine that boosts the immune response could improve the effect of conventional treatment for patients with chronic myeloid leukaemia

CML is caused by the breakage and swapping of chromosomes 9 and 22, which results in a shortened chromosome called the Philadelphia chromosome. Cells with the abnormal chromosome make a protein that encourages aberrant growth and division. Patients with CML can be treated with a drug called imatinib or interferon alfa.

20 Feb 2005

Heart repair linked to migraine relief

Migraine headache patients reported the painful attacks eased or even vanished after they underwent procedures to close abnormalities that allow blood to flow between the atria of their hearts, according to the results of two new studies in the current issue of the Journal of the American College of Cardiology.

16 Feb 2005

Safer approach to treating children with cystic fibrosis

Treating chest infections in young cystic fibrosis patients with an antibiotic once instead of three times daily is as effective and less toxic, conclude the results of a randomised trial published in this week’s issue of The Lancet.

10 Feb 2005

Ximelagatran effective for preventing blood clots and stroke

A medication that could simplify anticoagulation therapy, ximelagatran, was found to be as effective as other common therapies for preventing stroke and recurrent blood clots

9 Feb 2005

Many alcohol dependent HIV patients need assistance adhering to medications

Supervised medication delivery or simplified dosing regimens may be needed to ensure that HIV-infected patients with a history of alcohol problems stick to their medication regimens, according to a new study by researchers at Boston University Medical Center.

8 Feb 2005

Green tea boosts exercise endurance

Now that even baseball players may need to seek new, more natural performance aids, will Japanese green tea sets become standard in dugouts and athletic training tables around the world?

8 Feb 2005

Parents comfortable with vaccination for STIs for their children

Parents are generally accepting of the hypothetical scenario of vaccinating their adolescent children against infection, whether the infection is sexually transmitted or not, according to a study in the February issue of The Archives of Pediatrics and Adolescent Medicine.

7 Feb 2005

New study details trends in diagnosis, treatment of brain tumours

A two year study involving over 560 patients with the newly-diagnosed malignant brain tumors shows that patterns of care are varied and there is a need for new, detailed clinical guidelines for management of brain tumors. The study is published in the Feb. 2, 2005 issue of the Journal of the American Medical Association (JAMA).

3 Feb 2005

Calcium and vitamin D treatment alone can improve bone mineral density in Crohn's patients

According to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, the addition of popular bone building drugs to calcium and vitamin D therapy to treat bone loss associated with Crohn's disease is not beneficial.

1 Feb 2005

Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Whether a bioartificial kidney containing billions of donor kidney cells will help intensive care patients with kidney failure survive is under study at the Medical College of Georgia.

31 Jan 2005

Cardiac rehabilitation and secondary prevention protocols to imperative prevent recurrent heart attacks

Physicians should aggressively encourage patients to exercise and follow cardiac rehabilitation and secondary prevention protocols to prevent recurrent heart attacks, the American Heart Association recommends in its updated scientific statement on cardiac rehabilitation and secondary prevention of coronary heart disease.

27 Jan 2005

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine will begin in the Washington, DC area in a couple of months after the U.S. Food and Drug Administration conferred investigational new drug status on the vaccine.

27 Jan 2005

Tentative approval of co-packaged lamivudine/zidovudine fixed dose combination tablets and nevirapine tablets

The Food and Drug Administration (FDA) has announced the tentative approval of a co-packaged antiretroviral drug regimen manufactured by Aspen Pharmacare of South Africa for the treatment of HIV-1 infection in adults.

26 Jan 2005

New highly active agents against leishmaniasis

Parasitic diseases, especially leishmaniases and trypanosomiases, kill hundreds of thousands of people every year in the world, mainly in the countries of the South. The most severe form of leishmaniosis (kala-azar, the visceral form), induced by Leishmania donovani and L. infantum, affects about 500 000 people per year and proves fatal if no treatment is given.

25 Jan 2005

Schering and Novartis agree on joint commercialization of novel cancer drug

Schering AG, Germany announced today that, following regulatory approvals, it will co-promote the novel oral angiogenesis inhibitor PTK787/ZK 222584 (PTK/ZK) for all oncology indications together with Novartis Pharma AG in Europe, North America and Japan. This agreement will enable both Schering and Novartis to maximize the compound's full potential.

25 Jan 2005

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

Currently, the limited efficacy of conventional therapies, especially in the case of several oncology and autoimmune and inflammatory disorders (AIID), is creating the need for safe and effective treatment alternatives.

25 Jan 2005

More studies on risks and benefits of COX-2 inhibitors

A group of studies published in the January 24 issue of Archives of Internal Medicine add to the growing body of medical literature about the cardiovascular risks that may be associated with the class of pain-relieving drugs known as COX-2 inhibitors.

24 Jan 2005

New blood tests to soon replace painful bone marrow biopsies for leukemia and lymphoma patients

Quest Diagnostics Incorporated announced today that The University of Texas M. D. Anderson Cancer Center in Houston has granted the company exclusive use of five proprietary blood testing methods, which, once available in the form of laboratory diagnostic tests, may eliminate the need for painful and expensive bone marrow and other tissue extractions.

24 Jan 2005

Organon’s compound, Org 24448, selected to test efficacy of cognitive dysfunction in schizophrenia

The National Institute of Mental Health (NIMH) sponsored network called Treatment Units for Research on Neurocognition in Schizophrenia (TURNS) has selected Organon’s compound, Org 24448, to undergo testing as part of its effort to facilitate the development of medications to enhance cognition in patients with schizophrenia.

24 Jan 2005

Call for Anastrozole (Arimidex) to be the new preferred breast cancer treatment option

An international group of breast cancer experts called for the aromatase inhibitor (AI), anastrozole ('Arimidex'), to be considered as the new 'preferred treatment option' for postmenopausal women with early breast cancer.

24 Jan 2005

Efficacy News and Research

Vaccine that boosts the immune response could improve the effect of conventional treatment for patients with chronic myeloid leukaemia

Heart repair linked to migraine relief

Safer approach to treating children with cystic fibrosis

Ximelagatran effective for preventing blood clots and stroke

Many alcohol dependent HIV patients need assistance adhering to medications

Green tea boosts exercise endurance

Parents comfortable with vaccination for STIs for their children

New study details trends in diagnosis, treatment of brain tumours

Calcium and vitamin D treatment alone can improve bone mineral density in Crohn's patients

Bioartificial kidney containing billions of donor kidney cells under study at the Medical College of Georgia

Cardiac rehabilitation and secondary prevention protocols to imperative prevent recurrent heart attacks

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Tentative approval of co-packaged lamivudine/zidovudine fixed dose combination tablets and nevirapine tablets

New highly active agents against leishmaniasis

Schering and Novartis agree on joint commercialization of novel cancer drug

Monoclonal antibody therapeutics to fill vacuum left by ineffective conventional therapies

More studies on risks and benefits of COX-2 inhibitors

New blood tests to soon replace painful bone marrow biopsies for leukemia and lymphoma patients

Organon’s compound, Org 24448, selected to test efficacy of cognitive dysfunction in schizophrenia

Call for Anastrozole (Arimidex) to be the new preferred breast cancer treatment option

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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