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New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have discovered how a protein called Pmel17 is sorted by pigment cells in the skin and eye to make a fiber matrix that eventually sequesters melanin, the dark pigment found in skin, hair, and eyes.

28 Mar 2006

First trial to combine a biologic agent with a conventional chemotherapy agent for the treatment of ovarian cancer

Researchers found the addition of thalidomide to topotecan for the treatment of recurrent ovarian cancer significantly increases the response to therapy and the duration of progression free survival without additional toxicity.

28 Mar 2006

Gene therapy treatment for brain tumours and infections

In a study published in the March 15 issue of The Journal of Immunology, researchers at Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have developed a way to overcome immune privilege in the brain to eradicate potentially deadly brain tumors such as glioblastoma multiforme and other types of brain infections.

27 Mar 2006

Light activated anticancer drug targeted to DNA using cisplatin like sub-units: Coupling light absorbers to reactive metal centers

One of the most effective chemotherapy drugs against cancer is cisplatin because it attaches to cancer DNA and disrupts repair. However, it also kills healthy tissue. Many scientists are creating alternative drugs or cisplatin analogs in attempts to find treatments without side effects.

27 Mar 2006

Evolutionary biology research predicts precancerous tumors

In diverse ecosystems, packed with wildly different species, evolution whizzes along. As different species accumulate mutations, some adapt particularly well to their environment and prosper.

27 Mar 2006

Why do men choose one prostate treatment over another?

Men with prostate cancer generally make treatment decisions based on differences in the information they receive rather than their own preferences, according to a new review.

27 Mar 2006

Delayed prostate cancer intervention in low risk patients may not decrease ultimate chance for cure

A contemporary discussion exists whether patients with low-risk prostate cancer (CaP) are being overtreated with local treatment modalities. This is due to a combination of the older population affected and the slow doubling time of CaP.

23 Mar 2006

Positron emission tomography identifies esophageal cancer patients who will respond well to treatment

New research at Wake Forest University Baptist Medical Center shows that Positron Emission Tomography (PET) is more accurate than conventional imaging in identifying patients who have good responses to chemotherapy and radiation treatment - a finding that could one day help some patients avoid surgery.

22 Mar 2006

Computerized tomography guided percutaneous renal cryoablation with the patient under conscious sedation

When an event occurs once, we have a tendency to look at it as a phenomenon, but when it occurs twice, it begins to enter the realm of accepted reality.

21 Mar 2006

New technology - desorption electrospray ionization detects the boundaries of cancerous tumors

Researchers at Purdue University have shown how a new ultra-fast chemical-analysis tool has numerous promising uses for detecting everything from cancer in the liver to explosives residues on luggage and "biomarkers" in urine that provide an early warning for diseases.

21 Mar 2006

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy, according to a research team at Wake Forest University Baptist Medical Center.

21 Mar 2006

Study to Rituximab's potential to preserve insulin production in newly diagnosed type 1 diabetics

A drug used to treat lymphoma, rheumatoid arthritis and other immune disorders may enable newly-diagnosed type 1 diabetics to save some of their pancreas function and thereby reduce their susceptibility to long-term complications.

20 Mar 2006

Ginseng may improve survival and quality of life after a diagnosis of breast cancer

Ginseng, one of the most widely used herbs in traditional Chinese medicine, may improve survival and quality of life after a diagnosis of breast cancer, according to a recent study by Vanderbilt-Ingram Cancer Center researchers.

19 Mar 2006

EntreMed announces new U.S. Patent - "Estrogenic Compounds as Anti-Mitotic Agents"

EntreMed has announced the issuance of U.S. Patent No. 7,012,070 covering methods of treatment for a broad range of indications with its lead clinical-stage compound, 2-methoxyestradiol (2ME2).

17 Mar 2006

Antibody may reduce or eliminate tumors

San Diego State University researcher Roger Sabbadini has brought scientists one step closer to finding a cure for cancer with the creation of an antibody that hinders the growth of tumors by preventing blood vessel formation.

17 Mar 2006

African American women urged to confront colorectal cancer

Despite having the greatest risk of developing and dying from colorectal cancer (CRC) of any gender, race or ethnicity, an astounding 96 percent of African American women do not consider themselves to be at high risk for the disease, according to a new Harris poll.

17 Mar 2006

Prostate cancer detected on repeat biopsies have more favorable tumor characteristics but similar recurrence rates

Prostate cancer (CaP) detected on repeat biopsy may reflect smaller volume tumors and less aggressive biological and clinical disease.

17 Mar 2006

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

Molecular and serum markers of prognosis in renal cell carcinoma have remained elusive. In large part, tumor (TNM) stage, Fuhrman grade, and patient performance status have stood the test of time as the most valuable factors in predicting patient outcome following surgery.

15 Mar 2006

10.2 million plastic surgery procedures performed in the U.S. in 2005

More than 10.2 million cosmetic plastic surgery procedures were performed in the United States in 2005, up 11 percent from 2004, according to statistics released by the American Society of Plastic Surgeons (ASPS).

15 Mar 2006

Impact of a scientific presentation on community treatment patterns for primary breast cancer

The oral presentation of data from a single study at a national scientific conference can have an important impact on patient treatment, even before study publication or Food and Drug Administration (FDA) approval

15 Mar 2006

Tumor News and Research

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

First trial to combine a biologic agent with a conventional chemotherapy agent for the treatment of ovarian cancer

Gene therapy treatment for brain tumours and infections

Light activated anticancer drug targeted to DNA using cisplatin like sub-units: Coupling light absorbers to reactive metal centers

Evolutionary biology research predicts precancerous tumors

Why do men choose one prostate treatment over another?

Delayed prostate cancer intervention in low risk patients may not decrease ultimate chance for cure

Positron emission tomography identifies esophageal cancer patients who will respond well to treatment

Computerized tomography guided percutaneous renal cryoablation with the patient under conscious sedation

New technology - desorption electrospray ionization detects the boundaries of cancerous tumors

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

Study to Rituximab's potential to preserve insulin production in newly diagnosed type 1 diabetics

Ginseng may improve survival and quality of life after a diagnosis of breast cancer

EntreMed announces new U.S. Patent - "Estrogenic Compounds as Anti-Mitotic Agents"

Antibody may reduce or eliminate tumors

African American women urged to confront colorectal cancer

Prostate cancer detected on repeat biopsies have more favorable tumor characteristics but similar recurrence rates

Thrombocytosis: A clinical marker of tumor aggressiveness in renal cell carcinoma

10.2 million plastic surgery procedures performed in the U.S. in 2005

Impact of a scientific presentation on community treatment patterns for primary breast cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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