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Capsaicin drives prostate cancer cells to kill themselves

Capsaicin, the stuff that turns up the heat in jalapeqos, not only causes the tongue to burn, it also drives prostate cancer cells to kill themselves, according to studies published in the March 15 issue of Cancer Research.

15 Mar 2006

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Scientists have gained valuable new insight into the biology of aggressive, incurable brain tumors

A research study published in the March issue of Cancer Cell uses gene expression profiling to identify molecular profiles and signaling pathways associated with tumor aggressiveness and disease progression.

15 Mar 2006

Scientists gain better understanding of the behavior of leukemic cells

Scientists have uncovered new information about what orchestrates the complex balance between blood stem cells and mature blood cells, a relationship that is often disrupted in leukemia.

15 Mar 2006

Man-made chemical compound targets and kills tumor cells

A man-made chemical compound called ARC causes tumor cells to die but leaves normal cells unharmed, researchers at the University of Illinois at Chicago report in a study highlighted in the March 15 issue of Cancer Research.

15 Mar 2006

Partial nephrectomy: urologists need to practice what we preach

There is no question in the urologic literature that partial nephrectomy (PN), particularly for renal masses ¡Ü 4cm, has demonstrated oncologic equipoise with radical nephrectomy (RN).

14 Mar 2006

Decitabine improves myelodysplastic syndrome treatment

A potent member of a new class of drugs increases survival in some patients with myelodysplastic syndrome (MDS), and may become the new standard of therapy for this group of pre-cancer disorders

14 Mar 2006

Components found in red wine can help prevent periodontal diseases

Periodontitis is a progressive infectious disease affecting the gums and bone that surround and support teeth, often causing tooth movement and leading to permanent tooth loss.

13 Mar 2006

New test for detecting small amounts of proteins in the blood

Researchers at the University of Pennsylvania School of Medicine have developed a paradigm-shifting method for detecting small amounts of proteins in the blood.

13 Mar 2006

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

New animal research suggests that two well-studied drugs, thalidomide and its derivative, lenalidomide, might extend the survival of patients with the neurological disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

9 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

Lilly launches phase III trial of Enzastaurin

One of the deadliest and rarest forms of cancer is the focus of a Phase III study initiated by Eli Lilly and Company today.

9 Mar 2006

ATF2 protein may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment

Researchers at Purdue University have discovered a molecular mechanism that may play a crucial role in cancer's ability to resist chemotherapy and radiation treatment and that also may be involved in Alzheimer's and heart disease.

9 Mar 2006

Metabolic switch required for cellular adaptation to hypoxia

Two new studies in the March Cell Metabolism reveal a survival mechanism by which cells adapt to oxygen starvation by ratcheting down their demand.

9 Mar 2006

Is partial nephrectomy oncologically safe for tumors greater than 4cm?

Traditionally, nephron sparing surgery in the presence of a normal contralateral kidney is primarily advocated for tumors <= 4cm.

7 Mar 2006

Newly identified biomarkers may help reverse the ageing process

Lotions and potions that promise to remove wrinkles and other effects of aging crowd cosmetics aisle shelves, but do these treatments really work?

7 Mar 2006

Gene therapy approach used in creating new arteries for older patients does not appear to cause cancer

"This result is an encouraging step along the road to new tissues for patients to replace those that have failed or have been destroyed due to trauma or disease," she said.

7 Mar 2006

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.

1 Mar 2006

Fibulins inhibit both tumor growth and blood-vessel formation

Researchers at National Jewish Medical and Research Center report in the March issue of Cancer Research that a pair of promising proteins, known as fibulins 3 and 5, slow the growth of cancer tumors in mice by preventing blood vessels from sprouting. The proteins are promising candidates for use in cancer therapy.

1 Mar 2006