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New nanocarriers may effectively deliver therapeutic drug to GBM tumors

Glioblastoma multiforme, a cancer of the brain also known as "octopus tumors" because of the manner in which the cancer cells extend their tendrils into surrounding tissue, is virtually inoperable, resistant to therapies, and always fatal, usually within 15 months of onset.

20 Nov 2015

Urine-derived iPSCs model could help predict patient response to cholesterol-lowering drugs

We all know how important it is to keep our levels of blood cholesterol - especially the 'bad' variety - in check with a healthy diet and regular exercise. Although cholesterol is a key structural component of cell membranes and is vital for the biosynthesis of certain hormones and vitamins, high levels can lead to the formation of arterial plaques, which are a major risk factor for coronary heart disease.

20 Nov 2015

Scientists identify way to sensitize drug-resistant glioblastoma cells to chemotherapy

Scientists from the Virginia Tech Carilion Research Institute and clinicians from Carilion Clinic have discovered how to sensitize drug-resistant human glioblastoma cells to chemotherapy.

20 Nov 2015

Lilly, Merck expand oncology clinical trial collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced the extension of an existing collaboration to evaluate the safety and efficacy of the combination of Lilly's ALIMTA (pemetrexed for injection) and Merck's KEYTRUDA (pembrolizumab) in a pivotal Phase III study in first-line nonsquamous non-small cell lung cancer (NSCLC).

19 Nov 2015

New drug combination may reduce need for complex regimens to treat hepatitis C

The prognosis for people with hepatitis C has improved dramatically in the last few years, thanks to the introduction of direct-acting anti-viral medications, including Harvoni (the brand name for a combination of ledipasvir and sofosbuvir) and Viekira Pack (a mix of ombitasvir, paritaprevir, ritonavir and dasabuvir).

19 Nov 2015

Uninsured, low-income breast cancer patients less likely to continue hormonal therapy

A University of Colorado Cancer Center study published in the journal Breast Cancer Research and Treatment shows that breast cancer patients whose health insurance plans included prescription drug benefits were 10 percent more likely to start important hormonal therapy than patients who did not have prescription drug coverage.

19 Nov 2015

New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

New insulin pill shows promise as novel form of therapy for diabetes

An insulin pill being developed by researchers at UC Santa Barbara may in the near future give another blood sugar management option to those who suffer from diabetes. The novel drug delivery technology may also apply to a wide spectrum of other therapies.

19 Nov 2015

IMB scientists unravel complex regulatory mechanism involved in brain development

Scientists at the Institute of Molecular Biology in Mainz have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops. It also harbors potential for regenerative medicine.

19 Nov 2015

VA announces new ROPA program to improve radiation therapy cancer care for Veterans

The Department of Veterans Affairs today announced a new Radiation Oncology Practice Assessment (ROPA) program to leverage recent advances in information technology to improve radiation therapy cancer care for our nation's Veterans.

19 Nov 2015

IQWiG finds no added benefit for insulin degludec/liraglutide in adults with type 2 diabetes

The fixed combination of the two drugs insulin degludec and liraglutide (trade name: Xultophy) has been approved since June 2015 also in adults with type 2 diabetes mellitus when oral antidiabetics (OADs) combined with a GLP-1 receptor agonist do not provide adequate glycaemic control. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether this fixed combination offers an added benefit over the appropriate comparator therapy (ACT).

19 Nov 2015

Potential treatment strategy for glycogen storage disease

Researchers from the Duke-NUS Graduate Medical School Singapore and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.

18 Nov 2015

Gamma interferon may have potential to prevent Ebola infection

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

18 Nov 2015

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the official initiation of construction for its cell and gene therapy manufacturing centre.

18 Nov 2015

Duchenne muscular dystrophy could directly affect muscle stem cells

A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.

18 Nov 2015

Benchmark set by new supportive Jenx products

Jenx is launching a new bright, simple and flexible Therapy Bench to help offer children real benefit without the need to undergo formal assessment.

18 Nov 2015

Low vitamin D levels may limit effectiveness of HIV treatment

A University of Georgia researcher has found that low levels of vitamin D may limit the effectiveness of HIV treatment in adults.

18 Nov 2015

Use of azithromycin early reduces risk of recurrent, severe LRTI among young children

Among young children with histories of recurrent severe lower respiratory tract illness (LRTI), the use of azithromycin early during an apparent RTI compared with placebo significantly reduced the risk of experiencing progression to severe LRTI, according to a study in the November 17 issue of JAMA.

18 Nov 2015

UCLA researchers find new way to reduce ascites with minimal side effects

Women who have ovarian cancer often develop a condition called ascites, which is a buildup of fluids in the abdomen. The most common treatment for ascites is puncturing the abdomen and manually draining the fluid, which is painful and risky and must be repeated every few weeks.

18 Nov 2015

Matthew Teeter recognized with 2015 John Charles Polanyi Prize for research in joint replacement

Matthew Teeter, PhD, an assistant professor at Western University's Schulich School of Medicine & Dentistry and researcher at Lawson Health Research Institute, is a winner of the 2015 John Charles Polanyi Prize. The $20,000 award recognizes the excellence of Teeter's research in joint replacement.

18 Nov 2015

Therapy News and Research

New nanocarriers may effectively deliver therapeutic drug to GBM tumors

Urine-derived iPSCs model could help predict patient response to cholesterol-lowering drugs

Scientists identify way to sensitize drug-resistant glioblastoma cells to chemotherapy

Lilly, Merck expand oncology clinical trial collaboration

New drug combination may reduce need for complex regimens to treat hepatitis C

Uninsured, low-income breast cancer patients less likely to continue hormonal therapy

New technique improves accuracy of CRISPR/Cas9 gene editing system

New insulin pill shows promise as novel form of therapy for diabetes

IMB scientists unravel complex regulatory mechanism involved in brain development

VA announces new ROPA program to improve radiation therapy cancer care for Veterans

IQWiG finds no added benefit for insulin degludec/liraglutide in adults with type 2 diabetes

Potential treatment strategy for glycogen storage disease

Gamma interferon may have potential to prevent Ebola infection

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

Duchenne muscular dystrophy could directly affect muscle stem cells

Benchmark set by new supportive Jenx products

Low vitamin D levels may limit effectiveness of HIV treatment

Use of azithromycin early reduces risk of recurrent, severe LRTI among young children

UCLA researchers find new way to reduce ascites with minimal side effects

Matthew Teeter recognized with 2015 John Charles Polanyi Prize for research in joint replacement

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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