Fluorescence News and Research

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Life Technologies announces end-to-end sequencing solution for whole human exome CNV analysis

Life Technologies Corporation today announced the first end-to-end sequencing solution for exon-level copy number variation analysis, which combines the Ion Reporter CNV data analysis workflow, the Ion AmpliSeq Exome Kit and the Ion Proton® System.

27 Aug 2013

Researchers make significant step in understanding and imaging protein synthesis

Researchers at Columbia University, in collaboration with biologists in Baylor College of Medicine, have made a significant step in understanding and imaging protein synthesis, pinpointing exactly where and when cells produce new proteins.

26 Aug 2013

Smartphone-based portable device to conduct kidney tests invented at UCLA

A lightweight and field-portable device invented at UCLA that conducts kidney tests and transmits data through a smartphone attachment may significantly reduce the need for frequent office visits by people with diabetes and others with chronic kidney ailments.

26 Aug 2013

Researchers receive $1M grant to research in biological components with solid-state electronics

An interdisciplinary team of researchers from Columbia University, led by Ken Shepard, professor of electrical engineering and biomedical engineering at Columbia Engineering and including Virginia W. Cornish, Helena Rubinstein Professor of Chemistry, and Lars Dietrich, assistant professor of biological sciences, has won a prestigious $1 million three-year grant from the W. M. Keck Foundation to advance their research in combining biological components with solid-state electronics, creating new systems that exploit the advantages of both.

23 Aug 2013

Biomedical spectroscopy suggests excess copper may be neurotoxic in Alzheimer's patients

Metals such as iron, copper, and zinc are important for many biological processes. In recent years, studies have shown that these nutritionally-essential metals are elevated in human Alzheimer's disease (AD) brains and some animal models of AD. Scientists are now exploring whether these metals are causing the neurodegeneration seen in AD or are indicative of other ongoing pathologic processes.

22 Aug 2013

Researchers identify gene that contributes to development of acute myeloid leukemia

Researchers at the University of Chicago Medicine Comprehensive Cancer Center (UCCCC) have identified a gene that contributes to the development of acute myeloid leukemia (AML). This pivotal finding follows 40 years of University of Chicago research that has slowly unraveled the genetic basis of leukemia.

21 Aug 2013

Arrays of nanoscale sensors detect flaws in drugs and help improve production

MIT chemical engineers have discovered that arrays of billions of nanoscale sensors have unique properties that could help pharmaceutical companies produce drugs - especially those based on antibodies - more safely and efficiently.

17 Aug 2013

LMU immunologists develop new technique to fight against tumors, autoimmune diseases

Immunologists at Ludwig-Maximilians-Universitaet (LMU) in Munich have come up with a new technique that can be used both to fight tumors and to treat autoimmune diseases. A new grant from the Federal Ministry for Education and Research will enable the method to be developed further.

14 Aug 2013

Study reports high survival rates for children with rare subtype of leukaemia

A pioneering genetic study means that children with a rare subtype of leukaemia have 75% less chance of their leukaemia recurring.

13 Aug 2013

Scientists present novel method to visualize how nuclear protein mobility changes following DNA damage

Understanding the cellular response to DNA strand breaks is crucial to decipher the mechanisms maintaining the integrity of our genome. In eukaryotic cells, the molecular events triggered by DNA damage are strongly influenced by the local chromatin environment surrounding the lesion. The ensuing DNA repair process, in turn, impacts on chromatin structure. In order to understand how these two fundamental processes are mutually connected, both chromatin rearrangements induced by DNA damage as well as DNA repair activity have to be visualized in living cells.

12 Aug 2013

Genetically engineered proteins may be promising new tool for mapping brain cell activity

Scientists used fruit flies to show for the first time that a new class of genetically engineered proteins can be used to watch nerve cell electrical activity in live brains. The results, published in Cell, suggest these proteins may be a promising new tool for mapping brain cell activity in multiple animals and for studying how neurological disorders disrupt normal nerve cell signaling.

9 Aug 2013

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

PerFix-Expose1 and PerFix-nc1, innovative new reagent kits for intracellular staining from Beckman Coulter Life Sciences, minimize sample manipulation for a streamlined workflow that delivers high quality results. Developed for use on Beckman Coulter’s Gallios1 and Navios2 series flow cytometers and compatible with all Beckman Coulter Life Sciences’ fluorochromes, the kits enable a clear focus on the cytoplasmic and nuclear compartments of the cell.

8 Aug 2013

Penn State researchers find that protein changes can control gene functions

A Penn State-led research team has found that changes to proteins called histones, which are associated with DNA, can control whether or not a gene is allowed to function. The changes may be important in maintaining the genes' "expression potential" so that future cells behave as their parent cells did.

8 Aug 2013

ASU expert receives $1.6 million grant to advance microscopy imaging research

At Arizona State University's Biodesign Institute, Nongjian (NJ) Tao has been designing advanced microscopy methods with the ambitious aim of capturing molecular-scale phenomena in living systems. The new techniques, which combine multiple imaging modalities, are poised to revolutionize the study of biology and the development of new drugs.

8 Aug 2013

High-tech laser technique offers control of gene therapy and genetic engineering method

The applications of gene therapy and genetic engineering are broad: everything from pet fish that glow red to increased crop yields worldwide to cures for many of the diseases that plague humankind.

8 Aug 2013

Researchers develop nanoprobe technique to help treat fatal diseases more effectively

Researchers at the University of Southampton, in collaboration with colleagues at the University of Cambridge, have developed a technique to help treat fatal diseases more effectively.

8 Aug 2013

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Investigators have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer's disease. A new study published in Restorative Neurology and Neuroscience sheds light on the mechanism underlying aluminum-induced neuronal cell death and identifies necrostatin-1 as a substance which counteracts several of aluminum's neurotoxic effects.

6 Aug 2013

Fluorescence News and Research

Life Technologies announces end-to-end sequencing solution for whole human exome CNV analysis

Researchers make significant step in understanding and imaging protein synthesis

Smartphone-based portable device to conduct kidney tests invented at UCLA

Researchers receive $1M grant to research in biological components with solid-state electronics

Biomedical spectroscopy suggests excess copper may be neurotoxic in Alzheimer's patients

Researchers identify gene that contributes to development of acute myeloid leukemia

Arrays of nanoscale sensors detect flaws in drugs and help improve production

LMU immunologists develop new technique to fight against tumors, autoimmune diseases

Study reports high survival rates for children with rare subtype of leukaemia

Scientists present novel method to visualize how nuclear protein mobility changes following DNA damage

Genetically engineered proteins may be promising new tool for mapping brain cell activity

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

Penn State researchers find that protein changes can control gene functions

ASU expert receives $1.6 million grant to advance microscopy imaging research

High-tech laser technique offers control of gene therapy and genetic engineering method

Researchers develop nanoprobe technique to help treat fatal diseases more effectively

New studies in mice support toxic role of aluminum in neurodegenerative conditions

Necrostatin-1: A substance which counteracts several of aluminum's neurotoxic effects

Study suggests silicon nanocrystals may be safe tool for diagnostic imaging in humans

METH use can make person more susceptible to fungal lung infection

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