Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Altheus Therapeutics initiates enrollment in Zoenasa Phase 2 study for ulcerative colitis

Altheus Therapeutics announced today it has randomized its first patient in a comparator-controlled Phase 2 efficacy study of Zoenasa, a novel combination therapy for ulcerative colitis (UC).

29 Aug 2012

Children with obesity face increased risk for gallstones

Children who are overweight or obese face an increased risk for gallstones, according to a Kaiser Permanente study published in the Journal of Pediatric Gastroenterology & Nutrition.

26 Aug 2012

Early exposure to antibiotics primes children for obesity later in life

Researchers at NYU School of Medicine have made a novel discovery that could have widespread clinical implications, potentially affecting everything from nutrient metabolism to obesity in children.

23 Aug 2012

International guidelines improve outcomes after dental trauma

Adhering to the current International Association of Dental Traumatology guidelines for emergency treatment and care of traumatized teeth results in significantly lower complication rates, report researchers in Clinical Oral Investigations.

21 Aug 2012

HRT linked to ulcerative colitis in postmenopausal women

Taking postmenopausal hormone replacement therapy increases the risk for ulcerative colitis, but not Crohn’s disease, a study shows.

17 Aug 2012

Labial minor salivary flow could diagnose xerostomia

A reduction in labial minor salivary gland flow rate indicates the presence of xerostomia more accurately than changes in stimulated whole salivary flow rates, report Japanese researchers.

16 Aug 2012

Study tracks effects of heavy PAE on growth and body composition throughout childhood

Although studies of alcohol's effects on fetal growth have consistently demonstrated deficits that persist through infancy, the data on long-term postnatal growth from human studies have been inconsistent. A new study of the effects of heavy prenatal alcohol exposure (PAE) on growth and body composition throughout childhood has found growth restrictions that persist through to nine years of age, as well as a delay in weight gain during infancy, both of which were exacerbated by iron deficiency.

16 Aug 2012

Tofacitinib drug shows promise against moderate-to-severe ulcerative colitis

An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine.

16 Aug 2012

Longer, conical miniscrews most successful for orthodontic anchorage

The length and shape of miniscrew implants used for orthodontic anchorage has an effect on their success, with longer, and conical rather than cylindrical screws significantly associated with success, report Italian researchers.

13 Aug 2012

Taro, Sun Pharma enter merger agreement

Sun Pharmaceutical Industries Ltd. and Taro Pharmaceutical Industries Ltd. announced today that they have entered into a merger agreement together with certain affiliates of Sun Pharma.

13 Aug 2012

Salvage surgery for oropharyngeal cancer needs due consideration

Japanese study results indicate a 5-year overall survival rate of 49% for oropharyngeal cancer patients treated with salvage surgery after initial treatment with chemoradiotherapy has failed.

9 Aug 2012

Alfa Wassermann, Salix enter license agreement for EIR formulation of rifaximin

Salix Pharmaceuticals, Ltd. and Alfa Wassermann S.p.A. today announced that they have entered into an exclusive agreement by which Salix has licensed rights in the United States and Canada to an extended intestinal release (EIR) formulation of rifaximin for gastrointestinal and respiratory indications, including Crohn's disease.

9 Aug 2012

Researchers call for digital rectal exam revival

Rates of digital rectal examination are low in clinical practice and levels of sufficient training in the technique may be in decline, the results of a US study suggest.

8 Aug 2012

Dental health linked to falls in Japanese elderly

Japanese study results indicate that elderly individuals with 19 or fewer teeth who do not wear dentures are at a greater risk for incident falls than their counterparts with 20 teeth or more.

7 Aug 2012

Adalimumab effective in maintaining remission in pediatric patients with Crohn's disease

Adalimumab (an anti-tumor necrosis factor [TNF] antibody) is effective in maintaining remission in certain pediatric patients with Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association.

7 Aug 2012

Screening tool could help oral cancer detection

Indian researchers report the development of a novel, simple screening tool with a high degree of accuracy for the detection of oral premalignancies that can be used in a general health setting without the need for much training or clinical experience.

2 Aug 2012