Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Study identifies a new potential pathway for developing therapeutics against Epstein-Barr virus

A new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).

19 Jan 2022

New pathways responsible for hepatocellular carcinoma identified

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. It is one of leading causes of cancer-related deaths globally, with more than 700,000 new cases and 600,000 estimated HCC deaths each year.

18 Jan 2022

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Cannabidiol may improve innate immune response against SARS-CoV-2

A recent study shows evidence that cannabidiol, an important active ingredient in the Cannabis sativa plant, can augment the antiviral innate immune response and prophylactically prime the innate antiviral response of cells – enabling in turn improved response against viruses such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2022

MAPK4 may play a key role in triple-negative breast cancer

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

Modular super-enhancer regulates gene expression involved in retina development

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell identity.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

Researchers identify gene expression signatures linked to suicide risk

Is risk of suicide in our genes? Findings of an international scientific team led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that gene expression studies could offer insights into the underlying causes of suicide, a highly complex public health problem that takes the lives of more than 800,000 people each year worldwide.

10 Jan 2022

Scientists shine new light on the complexity of vitamin B12 diseases

A team of researchers at Baylor College of Medicine and collaborating institutions has shed new light into the complexity of vitamin B12 diseases.

10 Jan 2022

Bacterial biofilms use a developmental patterning mechanism seen in plants and animals

Over the past several years, research from University of California San Diego biologist Gürol Süel's laboratory has uncovered a series of remarkable features exhibited by clusters of bacteria that live together in communities known as biofilms.

7 Jan 2022

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

Professor Ronald Evans will receive $1.2 million over four years as part of a Network Grant from the Larry L. Hillblom Foundation to examine a molecular pathway that regulates blood sugar and fat independent of insulin.

6 Jan 2022

Analyzing cell-free RNA could reliably predict preeclampsia

Imaging techniques such as ultrasound technologies and minimally invasive procedures are powerful tools for assessing pregnancy health and progression.

5 Jan 2022

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

5 Jan 2022

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

The Wistar Institute announces the initiation of a Phase 2 clinical study of VK-2019 in patients with advanced Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and lymphoma.

5 Jan 2022

Novel insight into the immune characteristics of bats

Many studies have indicated that bats are significant reservoirs of innumerable viruses, such as influenza, coronaviruses, and rabies. These studies have also reported that bats predominantly remain asymptomatic or develop mild diseases during viral infections caused by henipaviruses, Ebola virus, coronaviruses, etc.

4 Jan 2022

Research provides compelling insights into the complex nature of genomic imprinting in mice

Mammalian offspring inherit two versions, or alleles, of each gene with one allele from each biological parent. However, gene expression is tightly regulated and certain genes undergo the phenomenon of "genomic imprinting", which is where only the allele received by the male or the female parent is expressed.

4 Jan 2022

Research provides new insights on the architecture of yeast nuclear pore complex

Nuclear pore complexes (NPCs) are massive multi-protein complexes that act as passageways for the transport of molecules into and out of the nucleus.

3 Jan 2022

Gene Expression News and Research

Further Reading

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Study identifies a new potential pathway for developing therapeutics against Epstein-Barr virus

New pathways responsible for hepatocellular carcinoma identified

Researchers investigate the role of a key component of the circadian clock in heart disease

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Cannabidiol may improve innate immune response against SARS-CoV-2

MAPK4 may play a key role in triple-negative breast cancer

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Modular super-enhancer regulates gene expression involved in retina development

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

Researchers identify gene expression signatures linked to suicide risk

Scientists shine new light on the complexity of vitamin B12 diseases

Bacterial biofilms use a developmental patterning mechanism seen in plants and animals

Salk professor receives $1.2 million from Larry L. Hillblom Foundation for diabetes research

Analyzing cell-free RNA could reliably predict preeclampsia

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

Wistar announces initiation of Phase 2 clinical study of VK-2019 in patients with advanced head and neck cancer

Novel insight into the immune characteristics of bats

Research provides compelling insights into the complex nature of genomic imprinting in mice

Research provides new insights on the architecture of yeast nuclear pore complex

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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