Genomic News and Research

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High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

BGI Genomics, in collaboration with Southwest University, the State Key Laboratory of Silkworm Genome Biology, and other partners, has constructed a high-resolution pangenome dataset representing almost the entire genomic content in a silkworm.

30 Sep 2022

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

A new study demonstrated the efficacy of a newly engineered angiotensin-converting enzyme 2 (ACE2) based immunoadhesin against Omicron and other SARS-CoV-2 VOCs.

30 Sep 2022

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Researchers analyzed genomic sequences of MPXV obtained from 18 patients who contracted MPXV infection between June and July 2022.

30 Sep 2022

Pluripotent bat stem cells as a model to study novel viruses

Researchers generate induced pluripotent stem cells from bats using to establish bats as a novel in vivo model study species.

29 Sep 2022

Study offers insights into how COVID-19 damages the heart

University of Queensland researchers have discovered how COVID-19 damages the heart, opening the door to future treatments.

29 Sep 2022

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Researchers explored the SARS-CoV-2 genome using high-throughput genome sequencing to provide novel insights into how the novel SARS-CoV-2 Omicron BA.2.3.7 variant enters and spreads among the otherwise naïve Taiwanese population.

29 Sep 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

Researchers to use $1 million grant for improving blood cancer diagnosis and treatment

Adelaide researchers will use a $1 million grant to improve the diagnosis and treatment of blood cancers, which kill 16 Australians every day.

28 Sep 2022

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Researchers from Barts Cancer Institute (BCI) at Queen Mary University of London, the Italian Institute for Genomic Medicine, and the University of Milan have identified a novel role for a cancer-causing gene in controlling an important genetic process that underpins genetic variation in prostate cancer.

27 Sep 2022

Novel CRISPR-based method benefits further cancer studies

Researchers have identified a mechanism by which an oncogene commonly activated in cancer patients affects the growth rate of cells.

27 Sep 2022

CDC awards five state public health departments to establish the Pathogen Genomics Centers of Excellence network

Today, CDC announced 5-year awards to five state public health departments. The awards will establish the Pathogen Genomics Centers of Excellence network.

27 Sep 2022

NIH launches new program to better understand the function of every human gene

The National Institutes of Health is launching a program to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.

27 Sep 2022

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces its continuing commitment to the next generation of researchers and scientists with a call for registrations for its SPRI Grants for Genomic Research.

From Beckman Coulter Life Sciences 27 Sep 2022

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Researchers at the University of California San Diego have for the first time discovered a pattern of DNA mutations that links bladder cancer to tobacco smoking.

27 Sep 2022

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Researchers explored RRIs [long-range ribonucleic acid (RNA)-RNA interactions] in SARS-CoV-2 variants of concern genomes to assess evolutionary changes in SARS-CoV-2.

26 Sep 2022

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

In a new study, researchers investigated the receptor tropism and serological cross-reactivity for spike (S) protein receptor-binding domains from two clade 3 sarbecoviruses found in Russian Rhinolophus (horseshoe) bats.

26 Sep 2022

Common germline variants of APOE contribute to differential COVID-19 outcomes

Researchers investigated the relationship between APOE4 genotype and COVID-19 outcomes using genetic models of mice.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

Viruses exploit ability to sense the environment to maximize their infective yield

New UMBC-led research in Frontiers in Microbiology suggests that viruses are using information from their environment to "decide" when to sit tight inside their hosts and when to multiply and burst out, killing the host cell. The work has implications for antiviral drug development.

23 Sep 2022

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Tiny nets woven from DNA strands can ensnare the spike protein of the virus that causes COVID-19, lighting up the virus for a fast-yet-sensitive diagnostic test – and also impeding the virus from infecting cells, opening a new possible route to antiviral treatment, according to a new study.

23 Sep 2022

Genomic News and Research

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

Effectiveness of anti-SARS-CoV-2 immunoadhesin against omicron and other emerging variants

DNA metagenomic analyses of clinical samples from Monkeypox virus-infected individuals

Pluripotent bat stem cells as a model to study novel viruses

Study offers insights into how COVID-19 damages the heart

How a major COVID-19 outbreak occurred in a naïve and vaccinated population in Taiwan with a limited number of entry events

Exploring remdesivir resistance in COVID-19-infected transplant recipients

Researchers to use $1 million grant for improving blood cancer diagnosis and treatment

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Novel CRISPR-based method benefits further cancer studies

CDC awards five state public health departments to establish the Pathogen Genomics Centers of Excellence network

NIH launches new program to better understand the function of every human gene

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Study investigates long-range RNA-RNA interactions of SARS-CoV-2

Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

Common germline variants of APOE contribute to differential COVID-19 outcomes

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Viruses exploit ability to sense the environment to maximize their infective yield

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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