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Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

A common Asian spice and cancer-hampering molecules show promise in slowing the progression of mesothelioma, a cancer of the lung's lining often linked to asbestos. Scientists from Case Western Reserve University and the Georg-Speyer-Haus in Frankfurt, Germany, demonstrate that application of curcumin, a derivative of the spice turmeric, and cancer-inhibiting peptides increase levels of a protein inhibitor known to combat the progression of this cancer.

22 Sep 2014

Researchers find new method to measure modified protein structures in biological sample

Cells regulate protein functions in a wide variety of ways, including by modifying the protein structure. In an instant, a protein can take on another form and perform no or even the "wrong" function: in humans, proteins that fold wrongly can cause serious diseases such as Alzheimer's, Parkinson's or cystic fibrosis.

16 Sep 2014

Gut hormone-drug combination therapy more effective at improving type 2 diabetes

Combined treatment with a drug that mimics the action of a gut hormone and basal insulin is more effective at improving blood sugar control than other anti-diabetic treatments, with similar rates of hypoglycaemia (dangerously low blood sugar levels) and greater weight loss, a systematic review and meta-analysis published in The Lancet shows.

15 Sep 2014

GILZ protein key to preventing bone loss, researchers report

A small protein named GILZ appears to protect against the bone loss that often accompanies arthritis and its treatment, researchers report.

15 Sep 2014

Scientists develop synthetic amino acid that can impact 3D structure of bioactive peptides

One of the greatest challenges in modern medicine is developing drugs that are highly effective against a target, but with minimal toxicity and side-effects to the patient. Such properties are directly related to the 3D structure of the drug molecule.

1 Sep 2014

Freiburg biochemists discover new mechanisms of brain disease

The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has discovered how Alzheimer's disease damages mitochondria, the powerhouses of the cell.

29 Aug 2014

New biomarker may improve diagnosis of early-stage rheumatoid arthritis

A novel biomarker for rheumatoid arthritis (RA) has significant potential to help physicians better identify early-stage disease, when treatment can often arrest further disease progression and disability, according to a new study in The Journal of Rheumatology.

From Quest Diagnostics 28 Aug 2014

New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

Oxidized lipids are known to play a key role in inflaming blood vessels and hardening arteries, which causes diseases like atherosclerosis. A new study at UCLA demonstrates that they may also contribute to pulmonary hypertension, a serious lung disease that narrows the small blood vessels in the lungs.

28 Aug 2014

ZO Skin Health reveals two new ZO Medical formulations to address hyperpigmentation

ZO Skin Health, Inc. is excited to reveal two new products developed by Zein Obagi, MD to further enhance the ZO Skin Health Circle continuum of care – ZO Medical C-Bright 10% Vitamin C Serum and ZO Medical Brightalive Non-Retinol Skin Brightener.

26 Aug 2014

OMRF receives $14.5 million grant from NIH to continue research on anthrax

The National Institutes of Health has awarded the Oklahoma Medical Research Foundation a five-year, $14.5 million grant to continue its research on anthrax and the bacteria's effects on humans.

21 Aug 2014

New antibodies could pave way for more effective drugs to combat influenza infection

Research toward developing new antibodies at the Hebrew University of Jerusalem's Faculty of Medicine could pave the way for more effective drugs to combat influenza infection.

20 Aug 2014

Queen's University scientists make breakthrough in fight against hospital superbugs

Scientists at Queen's University Belfast have made a breakthrough in the fight against the most resistant hospital superbugs.

19 Aug 2014

Paediatric PAH treatment goals identified

Researchers from the Netherlands have identified three baseline variables that may qualify as treatment goals in children with pulmonary arterial hypertension.

14 Aug 2014

Mortality predictors REVEALed for PAH in systemic sclerosis

Elderly men and patients with low baseline systolic blood pressure are among those at a particularly high risk of death from pulmonary arterial hypertension associated with systemic sclerosis, a US study has found.

14 Aug 2014

Scientists identify gene that regulates sleep and wake rhythms

Scientists at the Salk Institute for Biological Studies have identified a gene that regulates sleep and wake rhythms.

14 Aug 2014

Researchers reprogram nonribosomal peptide synthetases for clickable amino acids

A single targeted mutation is enough to alter a natural peptide system so that it also incorporates non-natural amino acids into peptides, report Swiss scientists in the journal Angewandte Chemie.

13 Aug 2014

Bee, snake, scorpion venom could form basis of new generation of cancer-fighting drugs

Bee, snake or scorpion venom could form the basis of a new generation of cancer-fighting drugs, scientists will report here today.

12 Aug 2014

Experts examine how molecule in parasitic worms can effectively treat autoimmune diseases

Experts believe a molecule in parasitic worms could help explain why worm infections can effectively treat a range of autoimmune diseases, including multiple sclerosis, psoriasis, rheumatoid arthritis and lupus.

12 Aug 2014

Oncothyreon acquires Alpine Biosciences to enable targeted delivery of multiple therapeutic agents

Oncothyreon Inc., a biotechnology company specializing in the development of innovative therapeutic products for the treatment of cancer, today announced that it has acquired Alpine Biosciences, Inc., of Seattle, Washington, a privately held biotechnology company developing protocells, a nanoparticle platform technology designed to enable the targeted delivery of multiple therapeutic agents, including nucleic acids, proteins, peptides and small molecules.

12 Aug 2014

Cancer fighter may also help patients survive pneumonia

The tip of an immune molecule known for its skill at fighting cancer may also help patients survive pneumonia, scientists report.

5 Aug 2014

Peptides News and Research

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

Researchers find new method to measure modified protein structures in biological sample

Gut hormone-drug combination therapy more effective at improving type 2 diabetes

GILZ protein key to preventing bone loss, researchers report

Scientists develop synthetic amino acid that can impact 3D structure of bioactive peptides

Freiburg biochemists discover new mechanisms of brain disease

New biomarker may improve diagnosis of early-stage rheumatoid arthritis

New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

ZO Skin Health reveals two new ZO Medical formulations to address hyperpigmentation

OMRF receives $14.5 million grant from NIH to continue research on anthrax

New antibodies could pave way for more effective drugs to combat influenza infection

Queen's University scientists make breakthrough in fight against hospital superbugs

Paediatric PAH treatment goals identified

Mortality predictors REVEALed for PAH in systemic sclerosis

Scientists identify gene that regulates sleep and wake rhythms

Researchers reprogram nonribosomal peptide synthetases for clickable amino acids

Bee, snake, scorpion venom could form basis of new generation of cancer-fighting drugs

Experts examine how molecule in parasitic worms can effectively treat autoimmune diseases

Oncothyreon acquires Alpine Biosciences to enable targeted delivery of multiple therapeutic agents

Cancer fighter may also help patients survive pneumonia

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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