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Virtual reality training may be effective alternative to standard therapy after stroke

Using virtual reality therapy to improve arm and hand movement after a stroke is equally as effective as regular therapy, according to a study published in the November 15, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

ATS and JRS publish new guidelines for diagnosis and management of LAM

The American Thoracic Society and the Japanese Respiratory Society have published additional clinical practice guidelines regarding four specific questions related to the diagnosis of lymphangioleiomyomatosis (LAM) and management of pneumothoraces in patients with LAM.

15 Nov 2017

Parkinson's disease will soon become looming pandemic, research reveals

New research shows that the number of people with Parkinson's disease will soon grow to pandemic proportions. In a commentary appearing today in the journal JAMA Neurology, University of Rochester Medical Center neurologist Ray Dorsey, M.D. and Bastiaan Bloem, M.D., Ph.D., with Radboud University Medical Center in the Netherlands, argue that the medical community must be mobilized to respond to this impending public health threat.

13 Nov 2017

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Neurodegenerative diseases are incurable and debilitating conditions that result in progressive degeneration and death of nerve cells, which leads to problems with movement or mental functioning. Examples include Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

13 Nov 2017

Air pollution may exacerbate osteoporosis

Based on a study of nine million people, researchers at Columbia University's Mailman School of Public Health People report that people living amidst high levels of air pollution are more likely to suffer bone fractures from osteoporosis than those living in areas with less pollution.

10 Nov 2017

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Celgene Corporation recently announced results from two phase 3 trials evaluating the efficacy and safety of the drug ozanimod.

10 Nov 2017

Early intervention may be crucial to successful treatment of Friedreich's ataxia

New research published today in Disease Models & Mechanisms indicates that early intervention should be a key target in the development of new therapeutics for Friedreich's ataxia, as current treatments may be administered too late to target the disease effectively.

8 Nov 2017

Johns Hopkins scientists report first-ever creation of protein hydrogels inside living cells

Johns Hopkins cell biologists report what they believe is the first-ever creation of tiny protein-based gelatin-like clumps called hydrogels inside living cells.

7 Nov 2017

MRI scans of healthy military recruits reveal sacroiliac joint damage that mimics axial spondyloarthritis

The magnetic resonance imaging scans of healthy military recruits showed sacroiliac joint damage similar to that found in axial spondyloarthritis after just six weeks of intensive physical training, reinforcing the importance of exercising caution when interpreting MRI results, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

Low-energy ESWT shows promise for managing digital ulcers in patients with systemic sclerosis

Extracorporeal shock-wave therapy at low energy levels showed promise as a new treatment for digital ulcers in patients with systemic sclerosis, or scleroderma, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.

6 Nov 2017

New research reveals possible therapeutic target for controlling inflammation in the brain

New research published online in the Journal of Leukocyte Biology showed for the first time that mature monocytes (a specific type of white blood cell) express the CXCR7 receptor on their surface.

3 Nov 2017

Targeting blood-clotting protein may help treat multiple sclerosis and other diseases

Picture a bare wire, without its regular plastic coating. It's exposed to the elements and risks being degraded. And, without insulation, it may not conduct electricity as well as a coated wire. Now, imagine this wire is inside your brain.

2 Nov 2017

Inflammation in mid-life may be linked to brain shrinkage decades later

People who have biomarkers tied to inflammation in their blood in their 40s and 50s may have more brain shrinkage decades later than people without the biomarkers, according to a study published in the November 1, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The brain cell loss was found especially in areas of the brain that are affected by Alzheimer's disease.

2 Nov 2017

Gene therapy prevents age-related learning and memory problems in mice

Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona and the Vall d'Hebron Research Institute are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age-related learning and memory problems in mice.

31 Oct 2017

Study reveals unique molecules in the blood of people with MS

A breakthrough study led by the University of Sydney's Brain and Mind Centre and Royal Prince Alfred Hospital has revealed unique molecules in the blood of people with Multiple Sclerosis (MS) that could become definitive diagnostic biomarkers of the world's most common neurologic disability in young adults.

30 Oct 2017

Biogen and Ionis awarded 2017 Prix Galien USA Award for SPINRAZA

Biogen and Ionis have been awarded the prestigious 2017 Prix Galien USA Award for Best Biotechnology Product for SPINRAZA (nusinersen). The Prix Galien USA Award recognizes extraordinary achievement in scientific innovation that improves the state of human health. The award was presented at a ceremony in New York City on October 26, 2017.

30 Oct 2017

Novartis PARADIGMS study shows safety and efficacy of new treatment in pediatric MS patients

Novartis today announced full results from the positive Phase III PARADIGMS study, investigating the safety and efficacy of Gilenya (fingolimod) vs. interferon beta-1a, in children and adolescents (ages 10 to 17) with multiple sclerosis (MS).

30 Oct 2017

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

Longevity Biotech, Inc. has received an award from the National Multiple Sclerosis Society through Fast Forward, the Society's commercial research funding program, to evaluate LBT-3627 in preclinical models as a potential disease-modifying therapeutic agent.

28 Oct 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

Sclerosis News and Research

Virtual reality training may be effective alternative to standard therapy after stroke

Study identifies molecular pathway critical to development of fibrosis

ATS and JRS publish new guidelines for diagnosis and management of LAM

Parkinson's disease will soon become looming pandemic, research reveals

Scientists develop novel mouse model to capture pathology of sporadic ALS and FTD

Air pollution may exacerbate osteoporosis

Ozanimod effective against multiple sclerosis, enters New Drug Approval process with FDA

Early intervention may be crucial to successful treatment of Friedreich's ataxia

Johns Hopkins scientists report first-ever creation of protein hydrogels inside living cells

MRI scans of healthy military recruits reveal sacroiliac joint damage that mimics axial spondyloarthritis

Low-energy ESWT shows promise for managing digital ulcers in patients with systemic sclerosis

New research reveals possible therapeutic target for controlling inflammation in the brain

Targeting blood-clotting protein may help treat multiple sclerosis and other diseases

Inflammation in mid-life may be linked to brain shrinkage decades later

Gene therapy prevents age-related learning and memory problems in mice

Study reveals unique molecules in the blood of people with MS

Biogen and Ionis awarded 2017 Prix Galien USA Award for SPINRAZA

Novartis PARADIGMS study shows safety and efficacy of new treatment in pediatric MS patients

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

Researchers discover mechanism that corrects protein misfolding in plants

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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