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Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

Nitrate from plant sources linked to lower risk of mortality

New research from Edith Cowan University (ECU) has found that nitrate from plant sources is associated with a lower risk of mortality while nitrate from other sources such as animal-based foods, processed meat and tap water, is linked to a higher risk of mortality.

25 Jun 2024

US surgeon general declares gun violence ‘a public health crisis’

U.S. Surgeon General Vivek Murthy declared firearm violence a public health crisis, as gun deaths and injuries punctuate daily life in America.

25 Jun 2024

Therapists learn how to help farmers cope with stress before it’s too late

The farmers' co-op here is a center of hope every spring. It's where farmers buy seed and fertilizer for the summer's crops, and where they seek tips to maximize their harvest of corn and soybeans.

25 Jun 2024

Novel genetic predisposition to being overweight or obese identified

Researchers performed a case-control study to compare metabolic changes between individuals homozygous for a loss-of-function genetic variation in small integral membrane protein 1 (SMIM1) and the general population.

25 Jun 2024

Research shows gut bacteria's role in mental resilience and reduced anxiety

Researchers characterized brain-gut microbiome (BGM) patterns related to stress resilience.

25 Jun 2024

New research challenges current practices for premature babies

Giving very premature babies high concentrations of oxygen soon after birth may reduce the risk of death by 50 percent, compared to lower levels of oxygen says new research led by University of Sydney researchers.

25 Jun 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

MicroRNAs shed light on aggressive youthful type 2 diabetes

Type 2 diabetes in young people ages 10 to19 has more than doubled in the past 20 years, yet it remains difficult for physicians to predict who will be diagnosed and who will improve with treatment. A newly published study from the University of Oklahoma shows that measuring the circulating abundance of microRNAs – which affect insulin-producing beta cells in the pancreas – is likely as effective as measuring the level of sugar in the blood for determining how a young person with the condition will fare.

25 Jun 2024

Beyond genes, new research explores mechanics and calcium signaling

Using animals to study heart disease doesn't always translate well to human health outcomes, and human heart cells available for research don't work outside the human body.

25 Jun 2024

Multi-regional sampling uncovers hidden complexity in liver cancer

A study led by clinician-scientists and scientists from the National Cancer Centre Singapore (NCCS) and A*STAR's Genome Institute of Singapore (GIS) and funded by the National Research Foundation Singapore (NRF) has discovered unexpected molecular heterogeneity even within the same liver tumors. More than 40% of HCC harbors more than one molecular subtype within the same tumor and in these, the clinical outcomes for the patients are best predicted by the most aggressive subtype.

25 Jun 2024

RENEW system utilizes machine learning for rare disease diagnosis

At Mayo Clinic, the mission to solve the unsolvable is at the heart of every rare disease case. Each diagnosis is a testament to perseverance, innovation and the relentless pursuit of answers.

25 Jun 2024

Brain processes immediate goals faster than distant ones

How does our brain distinguish between urgent and less urgent goals? Researchers at the University of Geneva (UNIGE) and the Icahn School of Medicine in New York have explored how our brain remembers and adjusts the goals we set ourselves on a daily basis.

25 Jun 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Teleneurology offers solution to neurologist shortage

One of the first studies to examine patient acceptability of teleneurology and determine factors influencing acceptability across neurological conditions, has found teleneurology was highly acceptable across the full range of patients with different neurological diagnoses, including headache, movement disorders and other neurological symptoms and diagnoses. The study also determined that the more medical complexity -- having additional diseases -- was associated with increased patient satisfaction with teleneurology.

25 Jun 2024

Study links gene regulation to allergic airway inflammation

Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper T (Th2) cells and group-2 innate lymphoid cells (ILC2s). Both Th2 and ILC2 require high amounts of GATA-binding protein 3 (GATA3) for their maturation.

25 Jun 2024

Global food collapse looms amid heat and water stress, warns new study

By 2050, global food production could decline by up to 14% due to heat and water stress, leading to 1.36 billion more people experiencing severe food insecurity, highlighting the urgent need for climate change mitigation.

25 Jun 2024

Personal choices drive young adults' alcohol abstinence with cannabis as a common substitute

Personal decisions, such as disinterest and avoiding drunkenness, are the primary reasons young adults abstain from alcohol, with financial concerns also playing a significant role, according to a recent study.

24 Jun 2024

Quality Improvement Program for Missouri saves millions and enhances elder care

A researcher at the University of Missouri has developed a program that improves the quality of care and reduces avoidable hospitalizations in nursing homes - saving Missouri nursing homes and Medicare millions of dollars and allowing Missouri nursing homes to invest more in retaining their most skilled staff members.

24 Jun 2024