Immune System News and Research

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Cell-death receptor links cancer susceptibility and inflammation

For over 10 years, Wafik S. El-Deiry, MD, PhD, Professor of Medicine, Genetics, and Pharmacology at the University of Pennsylvania School of Medicine, has been pursuing a cancer-targeting molecule called TRAIL and its molecular partners.

28 Dec 2007

Novavax's new bird flu vaccine could bolster the arsenal against a pandemic

The drug company Novavax has announced that it's experimental avian flu vaccine has proved to be both safe and effective in Phase I/IIa trials in humans.

20 Dec 2007

Researchers prevent muscle weakness caused by myasthenia gravis

Severe muscle weakness caused by myasthenia gravis - a highly debilitating autoimmune disorder - can be prevented or reversed by blocking a key step in the immune response that brings on the disease, researchers at the Saint Louis University School of Medicine have found.

20 Dec 2007

Advanced melanoma - new treatment

University of Illinois at Chicago researchers are participating in a multi-center research trial to evaluate the safety and effectiveness of Allovectin-7, an investigational treatment for advanced melanoma.

20 Dec 2007

The blood-brain barrier: A misunderstood key to finding life-saving cures to brain disease

An international team of scientists that includes a Saint Louis University researcher suggest several strategies to propel research for treatments of brain diseases that include multiple sclerosis, Alzheimer's disease, obesity and stroke in the January issue of the Lancet Neurology.

20 Dec 2007

Researchers train the immune system to deliver virus that destroys cancer in lab models

An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system.

20 Dec 2007

Does treating worms in people with HIV slow progression to AIDS?

Of the 25 million people infected with HIV-1 in Africa, as many as half are thought to be co-infected with worms (helminths), and there is evidence that these worms may result in a more rapid progression of HIV infection to AIDS.

20 Dec 2007

Rituximab may be promising treatment for diabetes

An antibody used to treat certain cancers and rheumatoid arthritis appears to greatly delay type 1 diabetes in mice, Yale School of Medicine researchers report in the Journal of Clinical Investigation.

20 Dec 2007

Addition of antibiotics to MS therapy could slow down progression of the disease

Researchers from Louisiana State University in the U.S. are suggesting that the addition of antibiotics to standard drug therapy for multiple sclerosis, may slow down the progress of the disease.

19 Dec 2007

Researchers initiate gene therapy trial in patients with advanced skin cancer

Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center are the first in the region to have joined a nationwide clinical trial to evaluate the effectiveness of a gene therapy in patients with advanced melanoma which is aimed to help a patient ' s own immune system fight their cancer.

18 Dec 2007

Second-hand tobacco smoke increases allergies in children

Breathing in second-hand tobacco smoke in early infancy boosts the risk of developing allergies, suggests research published ahead of print in the journal Thorax .

18 Dec 2007

Research provides new information about the body's immune system

Researchers at Oregon Health & Science University have uncovered new information about the body's immune system in a study that suggests new strategies may be in order for protecting the country's aging population against disease.

18 Dec 2007

Medical College of Georgia selected as RNA laboratory for worldwide diabetes study

The Medical College of Georgia Center for Biotechnology and Genomic Medicine has been selected to isolate RNA and DNA from the blood of thousands of children involved in a worldwide study of the causes of type 1 diabetes.

18 Dec 2007

Intracellular bacterial communities in cystitis; rifapentine cures TB in mouse model; and more

A study published this week in the open access journal PLoS Medicine presents convincing evidence that intracellular bacterial communities (IBCs) commonly exist in women with bladder infections and may contribute to the recurrence of these infections.

18 Dec 2007

Hospitalizations for children with HIV drop by nearly two thirds

The number of infants under age 2 with HIV who were hospitalized fell by 64 percent between 1998 and 2005, according to the latest News and Numbers by the Agency for Healthcare Research and Quality.

18 Dec 2007

Omega-3 fatty acids for depression - new trial

Researchers at Cedars-Sinai Medical Center's Department of Psychiatry and Behavioral Neurosciences are seeking participants for a clinical trial examining whether two polyunsaturated Omega-3 fatty acids are effective treatments for depression.

18 Dec 2007

Bacteria that cause urinary tract infections invade bladder cells

Scientists at Washington University School of Medicine in St. Louis have found definitive proof that some of the bacteria that plague women with urinary tract infections (UTIs) are entrenched inside human bladder cells.

18 Dec 2007

Agent orange chemical, dioxin, attacks the mitochondria to cause cancer

Researchers with the University of Pennsylvania School of Veterinary Medicine have demonstrated the process by which the cancer-causing chemical dioxin attacks the cellular machinery, disrupts normal cellular function and ultimately promotes tumor progression.

18 Dec 2007

Controlling lupus - new drug targets found

Investigators at Hospital for Special Surgery have identified two new targets for drugs aimed at controlling lupus.

17 Dec 2007

Genetic cause of Kawasaki disease

Researchers from Japan's RIKEN SNP Research Center, collaborating with a team at the University of California, San Diego (UCSD), have discovered a new genetic variation that affects a child's risk of getting Kawasaki disease (KD), an illness characterized by acute inflammation of the arteries throughout the body.

17 Dec 2007