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New studies raise important questions about impact of statin therapy on effectiveness of flu vaccines

A new pair of studies suggests that statins, drugs widely used to reduce cholesterol, may have a detrimental effect on the immune response to influenza vaccine and the vaccine's effectiveness at preventing serious illness in older adults. Published in The Journal of Infectious Diseases, the findings, if confirmed by additional research, may have implications for flu vaccine recommendations, guidelines for statin use around the time of vaccination, and future vaccine clinical trials in seniors.

29 Oct 2015

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

The U.S. Food and Drug Administration has approved a viral melanoma therapy that was the focus of a phase III clinical trial led by Rutgers Cancer Institute of New Jersey Associate Director for Clinical Science and Chief Surgical Officer Howard L. Kaufman, MD, FACS.

29 Oct 2015

WHO report reveals significant reduction in TB deaths, but detection, treatment gaps still exist

The fight against tuberculosis is paying off, with this year’s death rate nearly half of what it was in 1990. Nevertheless, 1.5 million people died from TB in 2014. Most of these deaths could have been prevented, according to the World Health Organization’s Global Tuberculosis Report 2015, which was released today in Washington, DC.

29 Oct 2015

Latitude, summer daylight exposure make difference in results for children treated with growth hormone

The rate of growth in children varies with the season while higher latitude and greater summer daylight exposure makes a significant difference in results for children treated with growth hormone, according to new research from The University of Manchester.

29 Oct 2015

GDF10 molecule identified as a key player in repair mechanisms after stroke

Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke.

29 Oct 2015

Denis Mukwege to be honored with 2016 Penn Nursing Renfield Foundation Award for Global Women's Health

Decorated humanitarian and outspoken advocate for women's rights, Dr. Denis Mukwege, will receive the 2016 Penn Nursing Renfield Foundation Award for Global Women's Health for his work in treating and highlighting the plight of women in the war-torn eastern part of the Democratic Republic of the Congo (DRC). The award comes with a $100,000 cash prize. Mukwege will receive the honor during an event at the University of Pennsylvania on March 24, 2016.

29 Oct 2015

New radiotherapeutic bandage shows promise against squamous cell carcinoma in animal model

A radiotherapeutic bandage is being evaluated by researchers for efficacy against squamous cell carcinoma (SCC) in an animal model. These results could confirm the viability of a new and improved strategy for the radiotherapeutic treatment of skin cancer in the clinic. This work is being presented Oct. 28 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

29 Oct 2015

Oncolytic (cancer-killing) viral therapy approved in the U.S. for use against late-stage melanoma

The U.S. Food and Drug Administration announced on Oct. 27 that it has approved, for the first time, an oncolytic (cancer-killing) viral therapy in the United States. The drug was approved for use against late-stage melanoma, a deadly skin cancer that can be difficult to treat.

29 Oct 2015

Yervoy approved for patients at high risk of developing recurrence of melanoma after surgery

Today the U.S. Food and Drug Administration expanded the approved use of Yervoy (ipilimumab) to include a new use as adjuvant therapy for patients with stage III melanoma, to lower the risk that the melanoma will return following surgery.

29 Oct 2015

Cynosure obtains medical device license from Health Canada to market MonaLisa Touch for treatment of GSM symptoms

Cynosure, Inc. today announced that it has received a medical device license issued by Health Canada to market MonaLisa Touch® for the treatment of symptoms related to Genitourinary Syndrome of Menopause (GSM), including vaginal dryness, vaginal burning, vaginal itching, pain, dysuria and dyspareunia.

28 Oct 2015

Study shows restoring testosterone production in men does not impact their fertility

Restoring testosterone production in men may be as effective as replacing it, without compromising their fertility. Two phase III clinical trials show that a drug that restores the body’s natural production of testosterone has no negative effect on a man’s sperm count while a topical testosterone gel causes a significant drop.

28 Oct 2015

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

Researchers studying two generations of a family affected by pediatric acute lymphoblastic leukemia (ALL) have identified an inherited variation in the ETV6 gene that is associated with an increased risk of developing the disease. St. Jude Children's Research Hospital investigators led the study, which appears in the October 28 issue of the journal Lancet Oncology.

28 Oct 2015

New generation of incretin-based medicines allows coordinated action against diabesity

The new generation of incretin-based medicines will allow a coordinated action against the combination diabetes/obesity, also known as diabesity, in some cases with only a single weekly dose, and with the likelihood of additional beneficial effects on other health complications related to this condition, such as cardiovascular and neurodegenerative diseases.

28 Oct 2015

FDA approves Endo’s BELBUCA (buprenorphine) buccal film for use in patients with chronic pain

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc, and BioDelivery Sciences International, Inc., announced today that the U.S. Food and Drug Administration (FDA) has approved BELBUCA (buprenorphine) buccal film for use in patients with chronic pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

28 Oct 2015

Hiroshima University researchers report promising new avenue for treating hepatitis B

A promising new avenue for treating hepatitis B has been reported by researchers at Hiroshima University who have developed a new animal model of the disease.

28 Oct 2015

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Patients with advanced cancers who took a drug designed to relieve constipation caused by pain killers lived longer and had fewer reports of tumor progression than cancer patients who did not receive the drug, according to results presented October 27 at the 2015 meeting of the American Society of Anesthesiologists in San Diego. This is the first study in humans to associate opioid blockade with improved survival.

28 Oct 2015

Researchers identify role of cGAS enzyme in autoimmune diseases

Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.

28 Oct 2015

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

The development of a new method to grow three-dimensional organoid cultures of pancreatic tumors directly from patients' surgical tissue offers a promising opportunity for testing targeted therapies and drug responses and personalizing treatments in a rapid, cost-effective manner.

28 Oct 2015

Researchers compare effectiveness of combination therapy for black patients with asthma

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Recent laboratory findings provide novel insight into potential new therapeutic approaches for triple-negative breast cancer, a particularly difficult to treat and aggressive form of the disease.

28 Oct 2015

Therapy News and Research

New studies raise important questions about impact of statin therapy on effectiveness of flu vaccines

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

WHO report reveals significant reduction in TB deaths, but detection, treatment gaps still exist

Latitude, summer daylight exposure make difference in results for children treated with growth hormone

GDF10 molecule identified as a key player in repair mechanisms after stroke

Denis Mukwege to be honored with 2016 Penn Nursing Renfield Foundation Award for Global Women's Health

New radiotherapeutic bandage shows promise against squamous cell carcinoma in animal model

Oncolytic (cancer-killing) viral therapy approved in the U.S. for use against late-stage melanoma

Yervoy approved for patients at high risk of developing recurrence of melanoma after surgery

Cynosure obtains medical device license from Health Canada to market MonaLisa Touch for treatment of GSM symptoms

Study shows restoring testosterone production in men does not impact their fertility

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

New generation of incretin-based medicines allows coordinated action against diabesity

FDA approves Endo’s BELBUCA (buprenorphine) buccal film for use in patients with chronic pain

Hiroshima University researchers report promising new avenue for treating hepatitis B

Drug that relieves opioid-induced constipation may help some cancer patients live longer

Researchers identify role of cGAS enzyme in autoimmune diseases

New method to grow 3D pancreatic cancer organoid may help test drug responses and personalized treatments

Researchers compare effectiveness of combination therapy for black patients with asthma

Research provides novel insight into potential new therapeutic targets for triple-negative breast cancer

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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