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Removing metastatic disease from the diaphragm significantly increases survival rates in ovarian cancer patients

In a retrospective study looking back at a decade of surgeries, Mayo Clinic Cancer Center researchers have determined that surgery to remove metastatic disease from the diaphragm, in conjunction with other procedures to remove the primary diseased tissue in ovarian cancer patients, significantly increases survival rates.

12 Oct 2005

Fijiian seaweed shows potential to kill cancer cells, bacteria and the HIV virus

Researchers have discovered 10 new molecular structures with pharmaceutical potential in a species of red seaweed that lives in the shallow coral reef along the coastline of Fiji in the south Pacific Ocean.

12 Oct 2005

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

In studies with mice, treatment with a new monoclonal antibody that targets immune system B cells has shown considerable promise for treating leukemias, autoimmune diseases and transplant rejection, according to immunologists at Duke University Medical Center.

11 Oct 2005

New discoveries help explore the function of regulatory T cells in autoimmune disease and in cancer

More than 150 years after the discovery of Hassall's corpuscles in 1849, the function of these round blobs of cells in the human thymus gland has now been explained. The answer, in turn, ends an intense hunt for the origin of regulatory T cells that has been under way for years.

11 Oct 2005

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Altering the standard step-by-step procedure that takes women facing a mastectomy from diagnosis to surgery to reconstruction can improve the process and help in determining if immediate reconstruction is the best course of action, according to new research from the University of North Carolina at Chapel Hill.

10 Oct 2005

Important milestone towards more individually targeted and effective treatments for cancer patients

The research team has now identified crucial genes in a range of common cancers that have been reported to predict a patient's response to treatment. This follows the team's earlier success in studying a tumor suppressor gene associated with acute lymphoblastic leukaemia (ALL) in children.

9 Oct 2005

Mitochondria and apoptosis research

The story of how mitochondria are recruited during times of stress to choreograph apoptosis--the cell's dance of death--is a story that fails to tell which particular set of steps the cells use most often, according to investigators at St. Jude Children's Research Hospital and the La Jolla Institute of Allergy and Immunology (San Diego, CA).

9 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Large tumors that block the sinuses can be removed endoscopically through the nose

The endoscopic approach worked well not only to remove large inverted papillomas in 18 patients ages 36 to 74 but also to watch for regrowth of the tumors that have a high recurrence rate and a small chance of becoming cancer. Patients were treated as outpatients and 56 percent remained disease-free at 29 months.

5 Oct 2005

Study looks at childrens end-of-life care preferences

Pediatric cancer patients as young as 10 years old who are aware that their disease is incurable have the ability to participate meaningfully in discussions of their own end-of-life care with family members and the health care team, according to investigators at St. Jude Children's Research Hospital and Sydney Children's Hospital.

5 Oct 2005

Immature stem cells that proliferate to form brain tissues in mice can function for at least a year

New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year -- most of the life span of a mouse -- and give rise to multiple types of neural cells, not just neurons.

5 Oct 2005

Patients with a family history of multiple melanoma skin cancer are at increased risk of multiple primary melanomas

In 2005, there will be an estimated 62,000 new cases of invasive melanoma and an estimated 7,600 deaths due to melanoma in the United States, according to background information in the article. Melanoma is the fifth leading cancer in men and the sixth leading cancer in women in the United States.

4 Oct 2005

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA: The Journal of the American Medical Association.

4 Oct 2005

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Researchers at Jefferson Medical College and at the Wadsworth Center in New York have identified a gene defect in mice resulting in a range of abnormalities, from cyclical hair loss and skin cancer to severe problems in normal skin development.

4 Oct 2005

Rapid weight gain between the ages of 25 and 40 doubles likelihood of prostate cancer recurrence

Men who gain weight rapidly between the ages of 25 and 40 are twice as likely to have recurrence of prostate cancer after surgery as men without rapid rates of weight gain, researchers from University of Texas M. D. Anderson Cancer Center reported in the October 1 issue of "Clinical Cancer Research."

4 Oct 2005

New digital angiography flat panel system reduces the radiation dose to patients undergoing interventional treatment for liver cancer

The study compared the radiation dose to patient's skin during transcatheter arterial embolization, a procedure that blocks the flow of a blood to a tumor. Doses were assessed for 12 patients using a new angiography unit with a digital flat-panel system and 12 using a conventional unit for angiographic imaging.

4 Oct 2005

Gleevec's uses might expand even further

Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway. The Giessen lung researchers now issue a first report of this substance as a new target therapy for pulmonary hypertension

4 Oct 2005

Lab-made version of a human protein opens a new research avenue to better understand rheumatoid arthritis

A lab-made version of a human protein alleviates symptoms of both acute and chronic arthritis in mice and could be the basis for a new arthritis drug for people, report scientists from the National Institute of Allergy and Infectious Disease (NIAID), part of the National Institutes of Health (NIH).

3 Oct 2005

Tumor News and Research

Removing metastatic disease from the diaphragm significantly increases survival rates in ovarian cancer patients

Fijiian seaweed shows potential to kill cancer cells, bacteria and the HIV virus

New monoclonal antibody that targets immune system B cells shows promise for treating leukemias

New discoveries help explore the function of regulatory T cells in autoimmune disease and in cancer

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Important milestone towards more individually targeted and effective treatments for cancer patients

Mitochondria and apoptosis research

Gene variation may play fundamental role in the development and spread of cancer in the body

RPL26 and nucleolin play critical roles in controlling the production of p53

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Large tumors that block the sinuses can be removed endoscopically through the nose

Study looks at childrens end-of-life care preferences

Immature stem cells that proliferate to form brain tissues in mice can function for at least a year

Patients with a family history of multiple melanoma skin cancer are at increased risk of multiple primary melanomas

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

Researchers identify gene defect in mice that causes cyclical hair loss and skin cancer

Rapid weight gain between the ages of 25 and 40 doubles likelihood of prostate cancer recurrence

New digital angiography flat panel system reduces the radiation dose to patients undergoing interventional treatment for liver cancer

Gleevec's uses might expand even further

Lab-made version of a human protein opens a new research avenue to better understand rheumatoid arthritis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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