Immune System News and Research

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Sanofi Pasteur receives FDA approval of Menactra meningococcal vaccine for children

Sanofi Pasteur, the vaccines division of sanofi-aventis Group, announced today that the U.S. Food and Drug Administration (FDA) has granted licensure to expand the indication for its meningococcal conjugate vaccine, Menactra (Meningococcal [Groups A, C, Y and W-135] Polysaccharide Diphtheria Toxoid Conjugate Vaccine), to include children 2 years through 10 years of age.

22 Oct 2007

Ubiquitin builds up an immune response

Ubiquitin is a small protein, which can be attached to other cellular proteins, a process known as ubiquitination.

22 Oct 2007

Bacteria use plant defence for genetic modification

Bacteria that cause tumours in plants modify plant genomes by skilfully exploiting the plants' first line of defence.

22 Oct 2007

West Nile virus' spread through nerve cells linked to serious complication

Scientists believe they have found an explanation for a puzzling and serious complication of West Nile virus infection.

19 Oct 2007

Preventing tuberculosis reactivation

Tuberculosis (TB) is the leading cause of death due to infectious disease in the world today.

19 Oct 2007

Lilly and MacroGenics to develop and commercialize teplizumab

Eli Lilly and Company and MacroGenics, Inc. have announced that the two companies have entered into a global strategic alliance to develop and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next generation anti-CD3 molecules for use in the treatment of autoimmune diseases.

19 Oct 2007

Study supports the theory of the seasonal flu

Low temperatures and relative humidities have been linked to the rapid spread of influenza in a new study by researchers, led by Dr. Peter Palese, from the Mount Sinai School of Medicine.

19 Oct 2007

Immune cells found to promote formation of new blood vessels - potential for endometriosis treatments

A discovery in mice of immune cells that promote the formation of new blood vessels could lead to new treatments for endometriosis, a painful condition associated with infertility that affects up to 15 percent of women of reproductive age.

19 Oct 2007

T-cell exhaustion

A new study of immune cells battling a chronic viral infection shows that the cells, called T cells, become exhausted by the fight in specific ways, undergoing profound changes that make them progressively less effective over time.

19 Oct 2007

New insight into mechanisms by which E. coli colonize the intestines

Food poisoning caused by the bacteria enterohemorrhagic Eschericia coli (EHEC) O157:H7A results in severe abdominal cramps and bloody diarrhea.

19 Oct 2007

FDA expands approved age range for Menactra, bacterial meningitis vaccine

The U.S. Food and Drug Administration has expanded the approved age range for Menactra, a bacterial meningitis vaccine, to include children ages 2 to 10 years.

19 Oct 2007

Enzyme synergy shown to perpetuate sleeping sickness

The pathogenesis of the parasite African trypanosome (T. brucei) has been linked to a key protein switch, detailed in a new study by researchers at the University of Iowa and the Veterans Affairs Medical Center of Iowa City, led by Dr. John Donelson.

19 Oct 2007

Day care attendance early in life protects infants and young children from later developing asthma

The study, "Influence of early day care exposure on total IgE levels through age 3 years" can be found in the Articles in Press section of the JACI Web site, http://www.jacionline.org. The JACI is the peer-reviewed journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).

19 Oct 2007