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Discovery establishes a role for the gene Rsf-1 in ovarian cancer

Johns Hopkins Kimmel Cancer Center researchers have linked alterations in a gene, called Rsf-1, to the most deadly ovarian cancers. The scientists say the discovery is the first to establish a role for the gene in ovarian cancer and may lead to a test that can predict, early on, which patients will develop aggressive disease.

3 Oct 2005

New Stat1 and interferon findings

By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection.

28 Sep 2005

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

A new study shows that combining a technology called optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer from non-cancerous lesions--and potentially reduce the number of breast biopsies performed. The study appears in the October issue of the journal Radiology.

27 Sep 2005

New virus-based gene therapy delivery system to help fight cancer

A Mayo Clinic research team has devised a new virus-based gene therapy delivery system to help fight cancer. Researchers say their findings will help overcome hurdles that have hindered gene therapy cancer treatments.

27 Sep 2005

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

In a significant advance toward understanding a perplexing and painful neurological disorder, an international team of researchers has discovered gene mutations associated with an inherited chronic pain and weakness syndrome known as hereditary neuralgic amyotrophy (also called HNA).

27 Sep 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor-associated antigens.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

The relationship between tissue rigidity and tumor formation is fairly well established; however, what is not so well understood is what happens on a molecular level that contributes to such stiffness.

26 Sep 2005

New method of radiation treatment may improve the local control of breast cancer

A new method of radiation treatment may improve the local control of breast cancer significantly which, is very important to cancer sufferers because it can preserve the breast and may also reduce the spread of the disease.

26 Sep 2005

Surprising immune system cells discovery

Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Questionnaire helps identify women who have inherited genetic mutations that increase their risk for breast or ovarian cancer

A simplified way for patients to report and update their family medical histories could help identify women who have inherited genetic mutations that increase their risk for breast or ovarian cancer.

26 Sep 2005

No significant differences among different ethnic groups for breast cancer related to hormone replacement therapy

The study, published online September 16, 2005 in the International Journal of Cancer, the official journal of the International Union Against Cancer (UICC), did find that leaner women taking hormone replacement therapy had a relatively greater increase in breast cancer risks than heavier women.

26 Sep 2005

Researchers discover way to dramatically boost the output of immune system cells from the thymus

Mayo Clinic researchers have discovered a way to dramatically boost the output of immune system cells from the thymus, which may lead to improved cancer vaccines, as well as to ways to otherwise strengthen immune responses.

26 Sep 2005

New technique may provide a better way of monitoring response to melanoma treatment

A new study published in PLoS Medicine describes a way to measure the immune response in people treated with an experimental vaccine to melanoma.

26 Sep 2005

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. The finding may suggest new pharmaceutical therapies for treating a variety of diseases, including cancer.

26 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Next generation of effective viral-based therapies for cancer

Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.

21 Sep 2005

New evidence for a genetic pathway that is involved in the recurrence of breast cancer

A study published in the September issue of Cancer Cell provides new evidence for a genetic pathway that is involved in the recurrence of breast cancer and identifies a potential target for development of new anticancer therapeutics.

20 Sep 2005

Tumor News and Research

Discovery establishes a role for the gene Rsf-1 in ovarian cancer

New Stat1 and interferon findings

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

New virus-based gene therapy delivery system to help fight cancer

Discovered of gene mutations associated with hereditary neuralgic amyotrophy

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

New method of radiation treatment may improve the local control of breast cancer

Surprising immune system cells discovery

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Questionnaire helps identify women who have inherited genetic mutations that increase their risk for breast or ovarian cancer

No significant differences among different ethnic groups for breast cancer related to hormone replacement therapy

Researchers discover way to dramatically boost the output of immune system cells from the thymus

New technique may provide a better way of monitoring response to melanoma treatment

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

Change in gene may be underlying molecular defect in some colorectal cancers

Next generation of effective viral-based therapies for cancer

New evidence for a genetic pathway that is involved in the recurrence of breast cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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