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Targeted therapy shows immense benefit for patients with early stage NSCLC

According to findings led by researchers at Yale Cancer Center, treatment with the targeted therapy osimertinib following surgery significantly improves disease-free survival (DFS) in patients with early-stage, non-small cell lung cancer (NSCLC) with EGFR gene mutations.

29 May 2020

5-day Remdesivir dose works as well as the 10-day dose in COVID-19, study finds

With more than 5.8 million people infected with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the search is on for an effective SARS-CoV-2 vaccine or drug to treat COVID-19 disease.

28 May 2020

CBD treatment improves arthritis symptoms in dogs, study finds

A team led by researchers at Baylor College of Medicine in collaboration with Medterra CBD conducted the first scientific studies to assess the potential therapeutic effects of cannabidiol for arthritic pain in dogs, and the results could lead the way to studying its effect in humans.

28 May 2020

Transgenic mouse model of HLH may play key role in saving lives during COVID-19

A transgenic mouse developed at Cincinnati Children's to model the deadly childhood immune disease HLH (hemophagocytic lymphohistiocytosis) may play a key role in saving lives during the COVID-19 virus pandemic.

28 May 2020

Clinical trial advances treatment for multiple sclerosis

Researchers conducting a clinical trial to advance the treatment of multiple sclerosis successfully applied a new drug testing methodology which allows several treatment options to be trialled at once.

27 May 2020

COVID-19 Rapid Research Fund allows coronavirus research in Ontario and London

Sepsis is a life-threatening condition. It occurs when the body's response to an infection is out of balance, triggering hyperinflammation that can damage multiple organs.

27 May 2020

Doxycycline is not effective in reducing the growth of abdominal aortic aneurysm

A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called an abdominal aortic aneurysm, received no benefits from taking a common antibiotic drug to reduce inflammation.

27 May 2020

Investigational antiviral superior to standard of care for treating COVID-19 patients

The investigational antiviral remdesivir is superior to the standard of care for the treatment of COVID-19, according to a report published today in The New England Journal of Medicine.

27 May 2020

Montefiore and Einstein evaluate a new drug combination to fight COVID-19

Montefiore Health System Albert Einstein College of Medicine have begun the next stage of the Adaptive COVID-19 Treatment Trial (ACTT), to evaluate treatment options for people hospitalized with severe COVID-19 infection.

26 May 2020

First COVID-19 vaccine found to be safe, able to generate rapid immune response in phase 1 clinical trial

The first COVID-19 vaccine to reach phase 1 clinical trial has been found to be safe, well-tolerated, and able to generate an immune response against SARS-CoV-2 in humans, according to new research published in The Lancet.

22 May 2020

Analysis: Get ready for the vaccine — they’re never simple

If there is a silver lining to the flawed U.S. response to the coronavirus pandemic, it is this: The relatively high number of new cases being diagnosed daily — upward of 20,000 — will make it easier to test new vaccines.

21 May 2020

MIT researchers describe new methods for accelerating drug approvals during pandemics

In response to the COVID-19 pandemic, researchers from the Massachusetts Institute of Technology have published a pair of studies in a COVID-19 special issue of the Harvard Data Science Review, freely available via open access, describing new methods for accelerating drug approvals during pandemics and for providing more accurate measures of the probabilities of success for clinical trials of vaccines and other anti-infective therapies.

20 May 2020

FDA approves IND application by Octapharma USA for severe COVID-19 patients

The U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application submitted by Octapharma USA for a phase three clinical trial on the efficacy and safety of Octagam 10% [Immune Globulin Intravenous (Human)] therapy in COVID-19 patients with severe disease progression.

20 May 2020

Legal Cannabis hemp oil helps reduce chronic neuropathic pain in mice

Researchers examine the effectiveness of consuming hemp oil extracted from the whole Cannabis plant using a chronic neuropathic pain animal model.

20 May 2020

Researchers describe new methods to speed up drug approvals during pandemics

20 May 2020

Australian COVID-19 prevention trial begins for frontline and allied healthcare workers

COVID SHIELD is a major collaborative effort led by the Walter and Eliza Hall Institute of Medical Research in partnership with human data science company IQVIA.

19 May 2020

Modified clinical trial design to meet urgent community needs during COVID-19 pandemic

A new paper published online in the Annals of the American Thoracic Society describes a nimble, pragmatic and rigorous multicenter clinical trial design to meet urgent community needs in the face of the COVID-19 pandemic.

19 May 2020

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

The first patients have been dosed in a multi-regional Phase IIB randomized, placebo-controlled clinical trial for the treatment of hepatitis B-associated liver cancer.

19 May 2020

SWOG scientists to deliver online presentations at ASCO20 Virtual Scientific Program

Researchers from SWOG, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, will make 31 presentations as part of the ASCO20 Virtual Scientific Program, the online annual meeting of the American Society of Clinical Oncology (ASCO), which runs May 29-31.

19 May 2020

Global study to test whether antimalaria drug can prevent COVID-19 in health-care workers

With $9 million in philanthropic support, an international group of physicians and scientists is establishing a research network to evaluate promising therapies for COVID-19.

18 May 2020

Placebo News and Research

Targeted therapy shows immense benefit for patients with early stage NSCLC

5-day Remdesivir dose works as well as the 10-day dose in COVID-19, study finds

CBD treatment improves arthritis symptoms in dogs, study finds

Transgenic mouse model of HLH may play key role in saving lives during COVID-19

Clinical trial advances treatment for multiple sclerosis

COVID-19 Rapid Research Fund allows coronavirus research in Ontario and London

Doxycycline is not effective in reducing the growth of abdominal aortic aneurysm

Investigational antiviral superior to standard of care for treating COVID-19 patients

Montefiore and Einstein evaluate a new drug combination to fight COVID-19

First COVID-19 vaccine found to be safe, able to generate rapid immune response in phase 1 clinical trial

Analysis: Get ready for the vaccine — they’re never simple

MIT researchers describe new methods for accelerating drug approvals during pandemics

FDA approves IND application by Octapharma USA for severe COVID-19 patients

Legal Cannabis hemp oil helps reduce chronic neuropathic pain in mice

Researchers describe new methods to speed up drug approvals during pandemics

Australian COVID-19 prevention trial begins for frontline and allied healthcare workers

Modified clinical trial design to meet urgent community needs during COVID-19 pandemic

Phase IIB clinical trial initiated for treating hepatitis B-associated liver cancer

SWOG scientists to deliver online presentations at ASCO20 Virtual Scientific Program

Global study to test whether antimalaria drug can prevent COVID-19 in health-care workers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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