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Breakthrough antibody therapy shows significant promise against drug-resistant multiple myeloma

In its first clinical trial, a breakthrough antibody therapy produced at least partial remissions in a third of patients with multiple myeloma who had exhausted multiple prior treatments, investigators at Dana-Farber Cancer Institute and other organizations report today online in the New England Journal of Medicine.

27 Aug 2015

Researchers find that 26% of senior oncology patients use complementary or alternative medicines

Alternative medicines are widely thought to be at least harmless and very often helpful for a wide range of discomforts and illnesses. However, although they're marketed as "natural," they often contain active ingredients that can react chemically and biologically with other therapies.

27 Aug 2015

Education can empower clinicians to safely prescribe opioids for chronic pain sufferers

Educating clinicians on how to safely prescribe opioids can help decrease opioid misuse among chronic pain sufferers.

27 Aug 2015

Experts shed light on the exciting field of therapy research for inflammatory diseases

What is happening in the treatment research of the inflammatory autoimmune diseases? Experts from several fields of medicine shed their light on the exciting field of therapy research for the inflammatory (autoimmune) diseases.

27 Aug 2015

Edwards Lifesciences closes acquisition of CardiAQ Valve Technologies

Edwards Lifesciences Corporation, the global leader in the science of heart valves and hemodynamic monitoring, today announced that it has closed its acquisition of CardiAQ Valve Technologies, Inc., a privately held company and developer of a transcatheter mitral valve replacement system. Edwards announced last month that it had signed an agreement to acquire CardiAQ.

27 Aug 2015

ASTRO awards $675,000 to seven physician-researchers to advance radiation oncology research

The American Society for Radiation Oncology has selected seven leading physician-researchers to receive a total of $675,000 in awards and grants to advance radiation oncology research. Together, the seven funding grants, including ASTRO Junior Faculty Career Research Training Award, the ASTRO Residents/Fellows in Radiation Oncology Research Seed Award and the ASTRO/Radiation Oncology Institute Comparative Effectiveness Research Award, will support studies in radiation and cancer biology, radiation physics, translational research, outcomes/health services research and comparative effectiveness research within radiation oncology.

27 Aug 2015

Centenary Institute develops new therapeutic approach to prevent GVHD in blood cancer patients

Sydney’s Centenary Institute has developed a new therapeutic approach that could help to improve outcomes for patients undertaking treatment for blood cancer.

26 Aug 2015

Optimal aerobic exercise training may benefit patients with pulmonary arterial hypertension

A physical therapy researcher with the IU School of Health and Rehabilitation Services at Indiana University-Purdue University Indianapolis has been awarded a $465,000 National Institutes of Health grant to optimize aerobic exercise training for patients with pulmonary arterial hypertension, a goal data suggests could reduce morbidity and mortality among those with the disease.

26 Aug 2015

Immatics US launched to develop adoptive cellular therapies for treatment of various tumors

Immatics Biotechnologies GmbH and The University of Texas MD Anderson Cancer Center announced today the launch of Immatics US, Inc., a new company aiming at becoming a global leader in adoptive cellular therapies (ACT) for the treatment of a range of tumor types.

26 Aug 2015

New studies evaluate viral suppression rate of HIV-infected pregnant women at delivery

Pregnancy could be a turning point for HIV-infected women, when they have the opportunity to manage their infection, prevent transmission to their new baby and enter a long-term pattern of maintenance of HIV care after giving birth--but most HIV-infected women aren't getting that chance.

26 Aug 2015

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

In preliminary research, the detection of persistent leukemia-associated genetic mutations in at least 5 percent of bone marrow cells in day 30 remission samples among adult patients with acute myeloid leukemia was associated with an increased risk of relapse and reduced overall survival, according to a study in the August 25 issue of JAMA.

26 Aug 2015

Researchers examine how small wireless sensors integrated into orthopedic implants can help detect SSI

A team of researchers, led by Rensselaer Polytechnic Institute Professor Eric Ledet, will investigate whether small wireless sensors incorporated into orthopedic implants could be used to detect surgical site infections. The research is supported by a $429,560 grant from the National Institutes of Health.

26 Aug 2015

Moffitt researchers discover high BRCA mutation frequency in young black women with breast cancer

Women who have inherited mutations in the BRCA1 or BRCA2 genes are more likely to develop breast cancer or ovarian cancer, especially at a younger age. Approximately 5 percent of women with breast cancer in the United States have mutations in BRCA1 or BRCA2 based on estimates in non-Hispanic white women.

26 Aug 2015

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations - detected after initial treatment with chemotherapy - are associated with an increased risk of relapse and poor survival.

26 Aug 2015

Mental visual imagery training may improve AM/EFT functioning in RR-MS patients

Patients with relapsing-remitting multiple sclerosis (RR-MS), the most common form of the disease, often have deficits in two neuropsychological functions, autobiographical memory (AM) and episodic future thinking (EFT), which impact quality of life.

26 Aug 2015

New assessment tool under development can help detect physical traits of Klinefelter syndrome

Klinefelter syndrome is the most common disorder of the male sex chromosomes, yet is rarely diagnosed in children. A new assessment tool is being developed by researchers at Columbia University Medical Center (CUMC) to help pediatricians detect the physical traits of the syndrome. The tool could pave the way for early interventions that prevent and treat a range of physical, psychological, social, and cognitive impairments.

26 Aug 2015

FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

Boehringer Ingelheim today announced that both the U.S. Food and Drug Administration and the European Medicines Agency have accepted filing applications for afatinib for the treatment of patients with advanced squamous cell carcinoma (SCC) of the lung progressing after treatment with first-line chemotherapy.

26 Aug 2015

Chrono obtains second Fast Track SBIR grant award from NCI to support development of smoking cessation therapy

Chrono Therapeutics, a pioneer in digital drug therapy, today announced it has received a second Phase 1 and Phase 2 Fast Track Small Business Innovation Research (SBIR) grant award from the National Cancer Institute.

26 Aug 2015

First patient enrolled in CSL Behring's rVIIa-FP Phase II/III study to treat patients with hemophilia A or B with inhibitors

CSL Behring announced today that the first patient has been enrolled in its Phase II/III clinical study evaluating the pharmacokinetics (PK), efficacy, and safety of the company's recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP) for on-demand treatment in patients with congenital hemophilia A or B who have developed an inhibitor to factor VIII or factor IX replacement therapy.

26 Aug 2015

Sequenom, UC San Diego Moores Cancer Center collaborate to explore utility of liquid biopsy assay

Sequenom, Inc., a life sciences company committed to enabling healthier lives through the development of innovative products and services, today announced that it has entered into a clinical research collaboration with the University of California, San Diego Moores Cancer Center.

26 Aug 2015

Therapy News and Research

Breakthrough antibody therapy shows significant promise against drug-resistant multiple myeloma

Researchers find that 26% of senior oncology patients use complementary or alternative medicines

Education can empower clinicians to safely prescribe opioids for chronic pain sufferers

Experts shed light on the exciting field of therapy research for inflammatory diseases

Edwards Lifesciences closes acquisition of CardiAQ Valve Technologies

ASTRO awards $675,000 to seven physician-researchers to advance radiation oncology research

Centenary Institute develops new therapeutic approach to prevent GVHD in blood cancer patients

Optimal aerobic exercise training may benefit patients with pulmonary arterial hypertension

Immatics US launched to develop adoptive cellular therapies for treatment of various tumors

New studies evaluate viral suppression rate of HIV-infected pregnant women at delivery

Persistent leukemia-associated genetic mutations linked to increased risk of relapse, reduced overall survival

Researchers examine how small wireless sensors integrated into orthopedic implants can help detect SSI

Moffitt researchers discover high BRCA mutation frequency in young black women with breast cancer

Lingering cancer-related mutations linked to increased risk of relapse, poor survival in leukemia patients

Mental visual imagery training may improve AM/EFT functioning in RR-MS patients

New assessment tool under development can help detect physical traits of Klinefelter syndrome

FDA, EMA accept filing applications for Boehringer Ingelheim's afatinib to treat patients with advanced SCC of the lung

Chrono obtains second Fast Track SBIR grant award from NCI to support development of smoking cessation therapy

First patient enrolled in CSL Behring's rVIIa-FP Phase II/III study to treat patients with hemophilia A or B with inhibitors

Sequenom, UC San Diego Moores Cancer Center collaborate to explore utility of liquid biopsy assay

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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