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Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

ALK rearrangement has been demonstrated to be a potent oncogenic driver and a promising therapeutic target in non-small cell lung cancer (NSCLC). It defines a distinct molecular subset of NSCLC, in particular adenocarcinoma that can benefit by the treatment of ALK-inhibitors.

26 Jun 2013

Newly developed approach could benefit basic medical research and help detect H2S in environment

University of Oregon chemists have developed a selective probe that detects hydrogen sulfide (H2S) levels as low as 190 nanomolar (10 parts per billion) in biological samples.

25 Jun 2013

Sentinel lymph node biopsy for early breast cancer: an interview with Prof. Gordon Wishart, Anglia Ruskin University

Our current method, which is recommended by the Association of Breast Surgeons in the UK, involves the use of injections of blue dye and radioisotope to identify the first node(s) under the arm (axilla) called the sentinel nodes.

25 Jun 2013

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

In a study published in the June 19 online edition of the journal Nature, a scientific team led by researchers from the University of California, San Diego School of Medicine visually monitored the dynamic cellular events that take place when cardiac regeneration occurs in zebrafish after cardiac ventricular injury. Their findings provide evidence that various cell lines in the heart are more plastic, or capable of transformation into new cell types, than previously thought.

20 Jun 2013

Scientists create way to see structures that store memories in living brain

Oscar Wilde called memory "the diary that we all carry about with us." Now a team of scientists has developed a way to see where and how that diary is written.

20 Jun 2013

Researchers shed light on how rice blast fungus invades plant tissue

Like a stealthy enemy, blast disease invades rice crops around the world, killing plants and cutting production of one of the most important global food sources.

19 Jun 2013

New chemical probe confirms that hydrogen sulfide is generated by body's growing cells.

A new study confirms directly what scientists previously knew only indirectly: The poisonous "rotten egg" gas hydrogen sulfide is generated by our body's growing cells.

19 Jun 2013

New research reports that UnaG protein could lead to new liver test

Many scientists dream of making a single discovery that provides fundamental insight into nature, may be used to help save human lives, and can assist in the preservation of an endangered species. In new research reported in the journal Cell, a Japanese team is on the verge of accomplishing this nearly impossible feat.

17 Jun 2013

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor.

15 Jun 2013

Nervous system and nerve-growth factor play major role in arthritis

Arthritis is a debilitating disorder affecting one in 10 Canadians, with pain caused by inflammation and damage to joints.

14 Jun 2013

Nano-biosensors along with new imaging techniques can improve drug targeting in pancreatic cancer

UK and Australian scientists have been able to show ways in which we can markedly improve drug targeting of solid tumours, using tiny 'biosensors' along with new advanced imaging techniques.

12 Jun 2013

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.

10 Jun 2013

Researchers discover TRF1 gene that is important for nuclear reprogramming

Researchers are still fascinated by the idea of the possibility of reprogramming the cells of any tissue, turning them into cells with the capacity to differentiate into cells of a completely different type- pluripotent cells-and they are still striving to understand how it happens.

6 Jun 2013

Cells with amplified HER2 gene need to be considered carefully, study says

Biocept, Inc., a privately-held, CLIA certified laboratory testing company focused on detection and analysis of circulating tumor cells and circulating tumor DNA in cancer patients, reported the publication in the journal Cancer Medicine of a paper entitled "Discordance in HER2 gene amplification in circulating and disseminated tumor cells in patients with operable breast cancer" on research performed with collaborators from the University of Texas MD Anderson Cancer Center.

5 Jun 2013

Study: Mutations in gene NTRK1 cause a subset of lung cancers

To the list of oncogenic drivers of lung cancer that includes ALK, EGFR, ROS1 and RET, results of a University of Colorado Cancer Center study presented at ASCO 2013 show that mutations in the gene NTRK1 cause a subset of lung cancers.

4 Jun 2013

Human tumors with MET amplification respond to MET inhibitor drugs

A subset of colorectal cancers responds to anti-epidermal growth factor receptor (anti-EGFR) therapies, but develops resistance within months. Among cancers that develop resistance to anti-EGFR therapy, some showed overexpression of a gene called MET, according to a study published in the June issue of Cancer Discovery, a journal of the American Association for Cancer Research.

3 Jun 2013

Viral load: A new technique that helps doctors diagnose chronic viral diseases

To test the severity of a viral infection, clinicians try to gauge how many viruses are packed into a certain volume of blood or other bodily fluid. This measurement, called viral load, helps doctors diagnose or monitor chronic viral diseases such as HIV/AIDS and hepatitis.

31 May 2013

Fluorescence News and Research

Immunohistochemistry could be a reliable and cost-effective diagnostic approach for lung cancer

Newly developed approach could benefit basic medical research and help detect H2S in environment

Sentinel lymph node biopsy for early breast cancer: an interview with Prof. Gordon Wishart, Anglia Ruskin University

Researchers monitor dynamic cellular events that take place during cardiac regeneration in zebrafish

Scientists create way to see structures that store memories in living brain

Researchers shed light on how rice blast fungus invades plant tissue

New chemical probe confirms that hydrogen sulfide is generated by body's growing cells.

New research reports that UnaG protein could lead to new liver test

Penn researchers develop variant of mu opioid painkiller receptor to overcome side effects

Nervous system and nerve-growth factor play major role in arthritis

Nano-biosensors along with new imaging techniques can improve drug targeting in pancreatic cancer

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Researchers discover TRF1 gene that is important for nuclear reprogramming

Cells with amplified HER2 gene need to be considered carefully, study says

Study: Mutations in gene NTRK1 cause a subset of lung cancers

Human tumors with MET amplification respond to MET inhibitor drugs

Viral load: A new technique that helps doctors diagnose chronic viral diseases

University of Strathclyde uses new imaging technique to track nanomedicines' effects on patients

Protein presenilin plays critical role in controlling neuronal traffic on microtubule highways

Researchers develop multicolor fluorescence labeling method to identify tumor specific miRNAs

Industry Focus eBook - Fluorescence (1st edition) eBook

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo