Genome News and Research

RSS

Non-traditional gene fusions in luminal breast cancer: A new target for therapy

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

Genetic diversity important for plant survival in changing climate

In a recent study in PNAS, a team of researchers at the Max Planck Institute for Chemical Ecology in Jena, Germany, shows that a single mutation that has immediate effects on plant fitness is maintained over the long term in natural plant populations, despite theories predict the contrary.

21 Aug 2023

Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

Immediately after the infection of a cell in the throat or lungs, the SARS-CoV-2 virus works very hard to replicate, using the human cell's metabolic pathways to produce its proteins and make sure that its genetic material (the RNA genome) is copied.

21 Aug 2023

Anti-estrogenic therapies can suppress growth of ER-negative cancers

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

21 Aug 2023

Microbiome-directed foods boost child nutrition

Researchers reconstructed gut bacterial genomes.

21 Aug 2023

New genes linked to breast cancer risk identified

A large-scale international collaborative study lead by Professor Jacques Simard from Université Laval and Professor Douglas Easton at the University of Cambridge, UK, has identified new genes associated with breast cancer that could eventually be included in tests to identify women at increased risk.

18 Aug 2023

Can your screen time affect your bowel movements?

The causal relationship between leisure screen time and irritable bowel syndrome.

18 Aug 2023

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models.

17 Aug 2023

Study investigates the impact of rapid genome sequencing for infantile epilepsy

Epilepsy in infants ranges in severity and can leave caregivers with questions about their child's health. While genetic testing to help determine the cause of epilepsy is possible, comprehensive testing does not always happen routinely and it can take a long time, leaving families waiting for answers.

17 Aug 2023

The Alliance for Genomic Discovery announces founding biopharma members: AbbVie, Amgen, AstraZeneca, Bayer, and Merck

Illumina Inc., a global leader in DNA sequencing and array-based technologies, in collaboration with Nashville Biosciences, LLC, a leading clinical and genomic data company and wholly owned subsidiary of VUMC, today announced the five founding members of the Alliance for Genomic Discovery.

17 Aug 2023

Long DNA molecules reveal new scar types in HR-deficient cancers

DNA can be damaged by toxins, radiation, or even normal cell division, but human cells must continually fix DNA breaks to survive.

16 Aug 2023

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.

16 Aug 2023

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

New Cleveland Clinic research shows how mosquito-transmitted viruses – like Zika, West Nile, Yellow Fever and dengue viruses – hijack host cells to promote their own replication and infection.

16 Aug 2023

Evolutionary roadmap revealed: How SARS-CoV-2 adapted and evolved over three years

The evolutionary trends of amino acid alterations at a population scale.

16 Aug 2023

Study uses genomic data to produce high-resolution serial interval estimates for COVID-19

Researchers developed an approach for integrating whole-genomic viral sequences and epidemiological information for serial interval (SI) estimation.

16 Aug 2023

Copy number profiling provides insight as to why prostate cancer may become lethal

Researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients.

16 Aug 2023

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

15 Aug 2023

Genome News and Research

Non-traditional gene fusions in luminal breast cancer: A new target for therapy

Genetic diversity important for plant survival in changing climate

Study sheds light on how SARS-CoV-2 virus switches between replication and packaging

Anti-estrogenic therapies can suppress growth of ER-negative cancers

Microbiome-directed foods boost child nutrition

New genes linked to breast cancer risk identified

Can your screen time affect your bowel movements?

Study finds how low levels of the TET2 gene fuel rapid growth of acute myeloid leukemia

Study investigates the impact of rapid genome sequencing for infantile epilepsy

The Alliance for Genomic Discovery announces founding biopharma members: AbbVie, Amgen, AstraZeneca, Bayer, and Merck

Long DNA molecules reveal new scar types in HR-deficient cancers

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

Research shows how mosquito-transmitted viruses hijack host cells to promote infection

Evolutionary roadmap revealed: How SARS-CoV-2 adapted and evolved over three years

Study uses genomic data to produce high-resolution serial interval estimates for COVID-19

Copy number profiling provides insight as to why prostate cancer may become lethal

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Genetic determinants of retinol circulation and their impact on health

A computational model identifies metabolites associated with Parkinson's disease

Epigenetic drug-sensitive biomarkers for cancer

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News