Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Researchers find rare genetic variants that may help explain longevity in some CF patients

Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

25 Oct 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

New discovery could speed development and approval of antiviral drugs

New research shows that a new class of antiviral drugs works by causing the virus' replication machinery to pause and backtrack, preventing the virus from efficiently replicating. This discovery, made possible by a high-throughput experimental technique called "magnetic tweezers," could speed the development and approval of related antiviral drugs.

25 Oct 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

Research provides insight into how two stands of double helix separate during replication

Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated once and only once.

24 Oct 2017

Lung microbiome plays major role in asthma severity and response to treatment

While the microbiome has gained significant attention for its impact on digestive health in recent years, its effect on lung disease has largely remained unstudied.

24 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

New study explores how herpes simplex virus may change during familial transmission

A new study explores how herpes simplex virus might change when passed from one individual to another, information that may prove useful in future development of therapeutics and vaccines.

20 Oct 2017

Study identifies predictors of poor outcomes in Duchenne muscular dystrophy patients

A new study from UT Southwestern suggests that more people with Duchenne muscular dystrophy could live longer by identifying and more aggressively treating patients with certain risk factors.

20 Oct 2017

UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs

University of California San Diego researchers have developed the first 3D spatial visualization tool for mapping "'omics" data onto whole organs.

20 Oct 2017

Findings suggest e-cigarettes may be just as bad as traditional cigarettes

E-cigarettes appear to trigger unique immune responses as well as the same ones that cigarettes trigger that can lead to lung disease, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

20 Oct 2017

Researchers discover new function in gene-regulatory protein

Researchers at Umeå and Stockholm universities in Sweden and Johns Hopkins University School of Medicine in the US have published a new study in the journal Molecular Cell.

20 Oct 2017

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

A human gene called p53, which is commonly known as the "guardian of the genome," is widely known to combat the formation and progression of tumors. Yet, mutant forms of p53 have been linked to more cases of human cancer than any other gene.

19 Oct 2017

Scientists uncover surprising molecular link in critical cellular growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.

19 Oct 2017

Most ovarian cancers start in the fallopian tubes, study finds

Most - and possibly all - ovarian cancers start, not in ovaries, but instead in the fallopian tubes attached to them.

17 Oct 2017

Stress may just as harmful to our body as bad diet, BYU study finds

We all know that a poor diet is unhealthy, but a new BYU study finds that stress may just as harmful to our bodies as a really bad diet.

16 Oct 2017

Researchers use mixed realty viewer to visualize complex biological networks in 3D

They call it the "hairy ball." It's an unflattering name for two-dimensional representations of a complex biological network, a depiction of a system of linkages and connections so complex and dense that "it looks like a big mess," said Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute and director of the university's bioinformatics and computational biology program.

13 Oct 2017

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

Determining how proteins function on a molecular level is crucial to understanding the underlying basis for disease. Now scientists at the University of Notre Dame are one step closer to unraveling the mystery of how intrinsically disordered proteins work, according to new research published in Science

13 Oct 2017

Agilent collaborate with Doulix to promote SureVector cloning kits

Double Helix Technologies (Doulix) announced today a collaboration with Agilent Technologies Inc. to promote Agilent's SureVector next-generation cloning kits through Doulix’s web platform. Through this partnership, synthetic biologists will be able to choose among SureVector’s standard DNA parts to design custom plasmids using Doulix’s web platform.

From Agilent Technologies - Genomics 11 Oct 2017

Experts indicate new way via which tumor cells can respond to chemotherapy

An international group of researchers, with the participation of the members of the University of Seville and the Andalusian Centre of Molecular Biology and Regenerative Medicine has just published a study in the prestigious review Science, in which they describe a new methodology for making tumor cells behave when submitted to chemotherapy, which, in the hope of new treatments, continues to be a fundamental tool in the fight against cancer.

10 Oct 2017

Molecular Biology News and Research

Further Reading

Researchers find rare genetic variants that may help explain longevity in some CF patients

Researchers discover mechanism that corrects protein misfolding in plants

New discovery could speed development and approval of antiviral drugs

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

Research provides insight into how two stands of double helix separate during replication

Lung microbiome plays major role in asthma severity and response to treatment

Researchers discover new regulatory role for protein that links diet and disease

New study explores how herpes simplex virus may change during familial transmission

Study identifies predictors of poor outcomes in Duchenne muscular dystrophy patients

UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs

Findings suggest e-cigarettes may be just as bad as traditional cigarettes

Researchers discover new function in gene-regulatory protein

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

Scientists uncover surprising molecular link in critical cellular growth pathway

Most ovarian cancers start in the fallopian tubes, study finds

Stress may just as harmful to our body as bad diet, BYU study finds

Researchers use mixed realty viewer to visualize complex biological networks in 3D

Scientists one step closer to unraveling mystery of how intrinsically disordered proteins work

Agilent collaborate with Doulix to promote SureVector cloning kits

Experts indicate new way via which tumor cells can respond to chemotherapy

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