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Ionizing radiation can reduce stiffness of tumor cell microenvironment

Nearly half of all cancer patients receive radiation therapy to curb the growth of malignant cells. But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other biomolecules that surrounds cells and plays a vital role in their shape, movement and signaling functions.

3 Apr 2018

Genetic testing could help guide blood-thinner treatment after stent placement

Using genetic testing to inform which blood thinner to use following a procedure to open narrowed blood vessels resulted in significantly fewer complications among patients, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

3 Apr 2018

Researchers identify 200 mutations in non-coding DNA that play role in cancer

Most of the human genome - 98 percent - is made up of DNA but doesn't actually encode genes, the recipes cells use to build proteins.

2 Apr 2018

New PET imaging agent could help guide treatments for people with neurological diseases

Researchers have developed a new imaging agent that could help guide and assess treatments for people with various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis.

2 Apr 2018

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

Inhibition of the oncogenic kinase AKT, a key protein governing the cell cycle, was found to arrest cancer cell proliferation and triggered their programmed death by apoptosis.

2 Apr 2018

The Human Microbiome – A New Potential Fingerprint in Forensic Evidence?

Professor Jack Gilbert gives an overview of the Burglary Microbiome Project, which he discussed at Pittcon 2018.

From Pittcon 29 Mar 2018

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Each day, normal human cell tissues express a protein known as p53 that wages war against potential malignancies. However, between 30 and 40 percent of human breast cancers express a defective (mutant) form of p53 that helps cancer cells proliferate and grow.

27 Mar 2018

Study identifies genetic factors linked to severity of acute viral bronchiolitis

A scientific study conducted at the State University of Campinas (UNICAMP) in São Paulo State, Brazil, has identified genetic factors associated with the severity of acute viral bronchiolitis. The study was supported by the Sao Paulo Research Foundation - FAPESP. Its results were published in the journal Gene.

27 Mar 2018

Researchers develop comprehensive map of genetic risk factors for stroke

Stroke is a serious disease affecting blood flow to and from the brain, and is the second leading cause of death worldwide. Stroke is characterized by a sudden onset of neurological dysfunction, caused by a blood clot or hemorrhage in a cerebral artery. While many genetic variants and lifestyle behaviors have been identified as risk factors for stroke, the genetic basis for the disease is unknown.

26 Mar 2018

Increasing prevalence of functional mitral regurgitation related to severity of heart failure

One potential therapeutic concept for treating heart failure besides guideline directed medical therapy, is to correct any concomitant severe mitral valve insufficiency (mitral regurgitation). Despite numerous treatment options being available, it is still not clear which patients will benefit most from such an intervention.

26 Mar 2018

Research provides better understanding of how some cancer cells resist treatment

An international team of researchers led by Lucio Miele, MD, PhD, Professor and Chair of Genetics at LSU Health New Orleans School of Medicine, and Justin Stebbing, BM BCh MA, PhD, Professor of Cancer Medicine and Medical Oncology at Imperial College of Medicine in London, has found new genetic mutations that promote the survival of cancer cells.

23 Mar 2018

Pittcon 2018 ends in Orlando with $23 million economic impact

Pittcon 2018, the 69th Conference and Exposition for Analytical Chemistry and Applied Spectroscopy, ended on March 1, in Orlando, Florida with an economic impact to the city estimated at $23 million. This global event brought together approximately 11,415 conferees and exhibitor personnel (official numbers to be released at the end of March).

From Pittcon 23 Mar 2018

New computational method helps to identify tumor cell mutations with greater accuracy

A new computational method developed by researchers at the New York Genome Center allows scientists to identify rare gene mutations in cancer cells with greater accuracy and sensitivity than currently available approaches.

22 Mar 2018

Agendia receives CE mark for MammaPrint BluePrint Breast Cancer Recurrence and Molecular Subtyping Kit

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, today announces that its next-generation sequencing-based MammaPrint BluePrint Breast Cancer Recurrence and Molecular Subtyping Kit is now CE marked, enabling the Company to commercialize the device in Europe.

22 Mar 2018

Neuroscientists move closer to developing tools for deciphering brain function

A team of University of Missouri neuroscientists are inching closer to developing the tools needed to decipher the brain.

21 Mar 2018

Protein profiling reveals new prostate cancer mechanisms

A study by the University of Tampere in Finland used protein profiling to find new prostate cancer mechanisms that are not shown by aberrations at the genomic level. Several new potential biomarkers of prostate cancer were also found.

21 Mar 2018

Researchers discover 'missing mutation' in severe infant epilepsy

Researchers have discovered a "missing mutation" in severe infant epilepsy--long-suspected genetic changes that might trigger overactive, brain-damaging electrical signaling leading to seizures.

20 Mar 2018

Wales participates in the 100,000 Genomes Project

Wales has joined the 100,000 Genomes Project, the Welsh Government announced today. The project, now a UK-wide initiative, seeks to transform patient care, encourage genomic discovery and drive a thriving genomics sector.

From Genomics England 20 Mar 2018

Genomics England announces new partnership to improve efficiency of next-generation sequencing analysis

Today (8 January 2018) at the annual J.P. Morgan Healthcare Conference, Edico Genome and Genomics England announced a new partnership to strengthen the accuracy and consistency of next-generation sequencing data analysis in Genomics England’s Rare Disease Pilot.

From Genomics England 20 Mar 2018

‘Fast track’ project shows promising results in cancer whole genome analyses

One key aim of the 100,000 Genomes Project is to improve cancer care for NHS patients. Whole genome sequencing in cancer can enable clinicians to choose better treatments and improve outcomes for patients through personalized medicine.

From Genomics England 20 Mar 2018

Precision Medicine News and Research

Ionizing radiation can reduce stiffness of tumor cell microenvironment

Genetic testing could help guide blood-thinner treatment after stent placement

Researchers identify 200 mutations in non-coding DNA that play role in cancer

New PET imaging agent could help guide treatments for people with neurological diseases

Molecular inhibitors found to arrest tumor cell proliferation in lung cancer and mesothelioma

The Human Microbiome – A New Potential Fingerprint in Forensic Evidence?

Combination therapy effectively induces tumor cell death and reduces spread of breast cancer

Study identifies genetic factors linked to severity of acute viral bronchiolitis

Researchers develop comprehensive map of genetic risk factors for stroke

Increasing prevalence of functional mitral regurgitation related to severity of heart failure

Research provides better understanding of how some cancer cells resist treatment

Pittcon 2018 ends in Orlando with $23 million economic impact

New computational method helps to identify tumor cell mutations with greater accuracy

Agendia receives CE mark for MammaPrint BluePrint Breast Cancer Recurrence and Molecular Subtyping Kit

Neuroscientists move closer to developing tools for deciphering brain function

Protein profiling reveals new prostate cancer mechanisms

Researchers discover 'missing mutation' in severe infant epilepsy

Wales participates in the 100,000 Genomes Project

Genomics England announces new partnership to improve efficiency of next-generation sequencing analysis

‘Fast track’ project shows promising results in cancer whole genome analyses

Editorial Focus eBook - Proteomics eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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