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Researchers receive NIH grant to study dementia caused by cerebral small vessel disease

Researchers at Washington University School of Medicine in St. Louis have been awarded $7.5 million from the National Institutes of Health (NIH) to investigate a form of dementia caused by cerebral small vessel disease, the second-leading cause of dementia after Alzheimer's disease.

17 Dec 2024

Advancements in reinforcement learning for personalized patient care

Reinforcement Learning, an artificial intelligence approach, has the potential to guide physicians in designing sequential treatment strategies for better patient outcomes but requires significant improvements before it can be applied in clinical settings, finds a new study by Weill Cornell Medicine and Rockefeller University researchers.

17 Dec 2024

Genetic shifts in reproductive traits link to aging and health risks

This study explores the genetics of human reproductive traits, revealing links to aging, health outcomes, and longevity while highlighting the role of genetic factors in modern fertility shifts.

17 Dec 2024

Scientists discover key protein that helps cancer cells evade CAR T cell therapy

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have collared a tricky culprit that helps cancer cells evade CAR T cell therapy.

17 Dec 2024

Researchers uncover key mechanisms in blood vessel formation

The formation of blood vessels is a complex process involving the interplay of proteins and mechanic forces.

17 Dec 2024

Chemical compound lights up treatment-resistant cancers on imaging scans

Researchers have used a chemical compound to light up treatment-resistant cancers on imaging scans, in a breakthrough that could help medical professionals better target and treat cancer.

17 Dec 2024

Breakthrough in understanding influenza's protective coat opens path to new treatments

To fight the virus that causes influenza, one of the avenues being explored by scientists is the development of drugs capable of destabilizing its genome, made up of eight RNA molecules.

17 Dec 2024

Breakthrough discovery could lead to effective vaccine for S. aureus

Staphylococcus aureus (S. aureus) is a major cause of skin and soft tissue infections that can sometimes lead to sepsis and toxic shock syndrome.

16 Dec 2024

Balanced breakfasts improve heart and metabolic health in older adults

Older adults with metabolic syndrome consuming either low- or high-energy breakfasts or low-quality breakfasts faced higher triglycerides, increased body fat, and worse kidney function. Breakfasts providing 20-30% of daily energy and high-quality nutrients improved lipid profiles and metabolic health.

16 Dec 2024

Novel drug holds promise for treating Duchenne muscular dystrophy

A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration.

16 Dec 2024

Microbial bile acids affect colon cancer risk in opposite ways

Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats.

16 Dec 2024

Researchers gain new insights into the molecular changes leading to Rett syndrome

Researchers at Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital and collaborating institutions have gained new insights into the molecular changes leading to Rett syndrome, a severe neurological disorder caused by mutations in the MeCP2 gene encoding methyl-CpG binding protein 2 (MeCP2).

16 Dec 2024

Collaborative project seeks to close diagnostic gap in asthma care

Asthma affects more than 260M people worldwide and nearly 28M people in the U.S. alone, where, on average, 10 people die from attacks of the chronic disease each day.

16 Dec 2024

Dinuclear platinum(II) complexes could offer a more targeted approach to treating prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men.

16 Dec 2024

Yeast proteins show promise as natural emulsifiers in daily products

Mention emulsifiers and many people might be unaware what they are used for, but they are present in many daily products, from food to cosmetics.

16 Dec 2024

A new era of targeted therapy with antibody–drug conjugates

TBC

From Sino Biological Inc. 16 Dec 2024

Flavonoid kaempferol could offer natural relief for food allergies

Allergic diseases such as asthma, atopic dermatitis, and food allergies have been increasing in frequency over the last few years.

16 Dec 2024

New discovery reveals twisting action of molecular motors in the DNA

Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes.

16 Dec 2024

Protein-packed foods may not be as healthy as you think, study finds

Foods with protein claims often appear healthy but are nutritionally worse, with 91% classified as "less healthy" due to high sodium, fat, and sweeteners.

15 Dec 2024

Promising combination therapy could improve liver cancer outcomes

Dan G. Duda, DMD, PhD, of the Edwin L. Steele Laboratories for Tumor Biology and Department of Radiation Oncology at Massachusetts General Hospital, is the corresponding author of a paper published in Cancer Immunology Research, "Combination CXCR4 and PD1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma."

14 Dec 2024