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Charleston Laboratories begins Phase 1 study on CL-H1T migraine drug candidate

Charleston Laboratories, Inc., an emerging specialty pharmaceutical company, announced initiation of its second clinical development program with a Phase 1 study on its migraine drug candidate, CL-H1T.

3 Aug 2015

Shire acquires Foresight Biotherapeutics for $300 million

Shire plc announced today that it has acquired New York-based, privately held Foresight Biotherapeutics Inc. for $300 million.

3 Aug 2015

TWi Biotechnology gets notice of patent allowance covering use of AC-201 drug in diabetes treatment

TWi Biotechnology, Inc., today announced that it has received Notices of Allowance for AC-201, TWi Biotechnology's lead drug candidate, from the European Patent Office and the Patent Office of the Russian Federation for patent applications numbered 11766702.2-1460 and 2012147449, respectively.

3 Aug 2015

Isis Pharmaceuticals, AstraZeneca to develop antisense therapies for cardiovascular, metabolic, renal diseases

AstraZeneca and Isis Pharmaceuticals, Inc. today announced a strategic collaboration to discover and develop antisense therapies for cardiovascular, metabolic and renal diseases.

3 Aug 2015

BUSM researchers find new way to detect and treat basal-like breast cancer

A new way to detect - and perhaps treat - one of the deadliest types of breast cancer has been found. Led by researchers at Boston University School of Medicine (BUSM), the study appears online in Breast Cancer Research.

3 Aug 2015

Moderate and severe selective eating habits linked to depression, anxiety, shows study

Picky eating among children is a common but burdensome problem that can result in poor nutrition for kids, family conflict, and frustrated parents.

3 Aug 2015

Childhood cancer cells produce molecule that affects body's immune system to fight disease

Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for the body's immune cells, leaving them too physically drained to fight the disease, according to new research published in the journal Cancer Research today (Saturday).

3 Aug 2015

BRCA gene mutations and ovarian cancer: an interview with Dr Matulonis, Harvard Medical School

The BRCA gene encodes for the BRCA proteins, BRCA1 and BRCA2. These proteins are very important in repairing DNA, which they do by correcting double-stranded breaks.

2 Aug 2015

FDA accepts Mundipharma EDO's Investigational New Drug Application for EDO-S101

Mundipharma EDO GmbH (Early Development in Oncology) is pleased to announce that the United States Food and Drug Administration has accepted the company's Investigational New Drug Application ("IND") for EDO-S101, a fusion molecule to treat relapsed/refractory haematologic malignancies and solid tumours.

31 Jul 2015

Eisai, Halozyme partner to evaluate eribulin and PEGPH20 in HER2-negative metastatic breast cancer

Eisai Inc. announced today that its parent company Eisai Co., Ltd. (Headquarters: Tokyo, President and CEO: Haruo Naito) and Halozyme Therapeutics, Inc. (Headquarters: San Diego, California, President and CEO: Dr. Helen Torley) have signed a clinical collaboration agreement to evaluate Eisai's agent eribulin mesylate (brand name: Halaven, "eribulin") in combination with Halozyme's investigational drug PEGPH20 (PEGylated recombinant human hyaluronidase) in first line HER2-negative metastatic breast cancer.

31 Jul 2015

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Immunotherapy using monoclonal antibodies is a promising treatment strategy, and it might now be within reach: American scientists have successfully prepared an oligosaccharide enterobacterial antigen for which a monoclonal antibody has been developed. The study is published in the journal Angewandte Chemie.

31 Jul 2015

Taiwanese scientists propose advanced solution that can be applied to thermal cancer therapy

Precise targeting biological molecules, such as cancer cells, for treatment is a challenge, due to their sheer size. Now, Taiwanese scientists have proposed an advanced solution, based on a novel combination of previously used techniques, which can potentially be applied to thermal cancer therapy.

31 Jul 2015

Study: Positive reinforcement improves performance of ADHD kids on certain cognitive tasks

A little recognition for a job well done means a lot to children with Attention Deficit/Hyperactivity Disorder (ADHD) - more so than it would for typically developing kids.

31 Jul 2015

New non-invasive spinal cord stimulation helps paralyzed men voluntarily move their legs

Five men with complete motor paralysis were able to voluntarily generate step-like movements thanks to a new strategy that non-invasively delivers electrical stimulation to their spinal cords, according to a new study funded in part by the National Institutes of Health. The strategy, called transcutaneous stimulation, delivers electrical current to the spinal cord by way of electrodes strategically placed on the skin of the lower back.

31 Jul 2015

Researchers reconstruct ancient virus to improve gene therapy

Researchers at Massachusetts Eye and Ear/Schepens Eye Research Institute have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina. This discovery, published July 30 in Cell Reports, could potentially be used to design gene therapies that are not only safer and more potent than therapies currently available, but may also help a greater number of patients.

31 Jul 2015

New blood test could help diagnose severity of traumatic brain injury

A new blood test could help emergency room doctors quickly diagnose traumatic brain injury and determine its severity.

31 Jul 2015

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Indiana University-Purdue University Indianapolis researchers led by Jesse Stewart of the School of Science, have received a $2.6 million grant from the National Institutes of Health to conduct the first randomized controlled trial to determine whether depression treatment can help prevent the development of cardiovascular disease.

31 Jul 2015

Psychotropic medication use widespread among older adults, new study finds

Older Americans receive prescriptions for mental health medications at more than twice the rate that younger adults do, a new study finds.

31 Jul 2015

Cryoport to offer cryogenic logistics solutions to HemaCare

Cryoport, Inc., the leading provider of advanced cryogenic logistics solutions for the life sciences industry, serving markets including immunotherapies, stem cells, cell lines, clinical research organizations, vaccine manufacturers, animal health, and reproductive medicine, today announced that the Company will provide cryogenic logistics solutions to HemaCare Corporation, a leading global provider of high-quality biological material to the scientific community.

30 Jul 2015

HeartWare’s total revenues increase 13% to $73.6 million in second quarter 2015

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced total revenue of $73.6 million for the quarter ended June 30, 2015 compared to $70.1 million for the quarter ended June 30, 2014.

30 Jul 2015

Therapy News and Research

Charleston Laboratories begins Phase 1 study on CL-H1T migraine drug candidate

Shire acquires Foresight Biotherapeutics for $300 million

TWi Biotechnology gets notice of patent allowance covering use of AC-201 drug in diabetes treatment

Isis Pharmaceuticals, AstraZeneca to develop antisense therapies for cardiovascular, metabolic, renal diseases

BUSM researchers find new way to detect and treat basal-like breast cancer

Moderate and severe selective eating habits linked to depression, anxiety, shows study

Childhood cancer cells produce molecule that affects body's immune system to fight disease

BRCA gene mutations and ovarian cancer: an interview with Dr Matulonis, Harvard Medical School

FDA accepts Mundipharma EDO's Investigational New Drug Application for EDO-S101

Eisai, Halozyme partner to evaluate eribulin and PEGPH20 in HER2-negative metastatic breast cancer

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Taiwanese scientists propose advanced solution that can be applied to thermal cancer therapy

Study: Positive reinforcement improves performance of ADHD kids on certain cognitive tasks

New non-invasive spinal cord stimulation helps paralyzed men voluntarily move their legs

Researchers reconstruct ancient virus to improve gene therapy

New blood test could help diagnose severity of traumatic brain injury

IUPUI researchers receive NIH grant to study effect of depression treatment on cardiovascular disease

Psychotropic medication use widespread among older adults, new study finds

Cryoport to offer cryogenic logistics solutions to HemaCare

HeartWare’s total revenues increase 13% to $73.6 million in second quarter 2015

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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