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Increased awareness of fertility preservation options needed for young patients with cancer

A new study points to the need for increased awareness of fertility preservation options for young patients with cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study found that factors such as gender, education, and insurance status may impact whether patients and their physicians have discussions and take actions to preserve fertility during cancer treatment.

28 Jul 2015

Innovative approach to treating AAT deficiency

Researchers have demonstrated the feasibility of delivering an RNA that encodes for the protein alpha-1-antitrypsin (AAT)--which is missing or nonfunctional in the genetic disorder AAT deficiency--into cells in the laboratory, enabling the cells to produce highly functional AAT.

28 Jul 2015

Wayne State leads landmark study that examines clinical use of polymyxin B to treat superbugs

With the decline of the development of new antibiotics due to the complexity and expense of discovering them, there has been a rapid growth of antibiotic resistant pathogens that is one of the leading causes of death. With the help of a nearly $4.9 million, 5-year grant from the National Institute for Allergy and Infectious Diseases of the National Institutes of Health, Wayne State University School of Medicine researchers are leading a landmark multi-center, international study that will provide essential information to clinicians for use of polymoxin B in critically ill patients where no other treatments will work.

28 Jul 2015

New technique improves survival time for glioblastoma patients by 50%

The rapid spread of a common and deadly brain tumor has been slowed down significantly in a mouse model by cutting off the way some cancer cells communicate, according to a team of researchers that includes UF Health faculty.

28 Jul 2015

Protein imbalances within cells can cause ovarian cancer

Cancer can be caused solely by protein imbalances within cells, a study of ovarian cancer has found. The discovery is a major breakthrough because, until now, genetic aberrations have been seen as the main cause of almost all cancer.

28 Jul 2015

Mobile Stroke Treatment Units can improve survival rates and enhance patient's chance of recovery

Two new studies presented today at the Society of NeuroInterventional Surgery 12th Annual Meeting in San Francisco, report that Mobile Stroke Treatment Units (MSTUs) can significantly reduce the time it takes to diagnose and treat patients for stroke, greatly improving survival rates and enhancing a patient's chance of recovery.

28 Jul 2015

FDA grants Fast Track Designation to TxCell’s Ovasave for treatment of Crohn’s disease

TxCell SA, a biotechnology company developing innovative, personalized cell-based immunotherapies using antigen specific regulatory T-cells for severe chronic inflammatory and autoimmune diseases, announces today that the United States Food and Drug Administration has granted Fast Track Designation to TxCell’s lead product Ovasave for the treatment of moderate to severe Crohn’s disease.

28 Jul 2015

GLP-2 therapy may help fight neonatal parenteral nutrition-associated liver disease

A new study finds that exogenous glucagon-like peptide 2 (GLP-2) treatment may help fight neonatal parenteral nutrition-associated liver disease (PNALD).

28 Jul 2015

Landmark study to provide critical information for optimized use of polymyxin B in critically ill patients

28 Jul 2015

Research sheds light on new therapeutic options for acute lymphoblastic leukemia

In industrialized countries like in Europe, acute lymphoblastic leukemia is the most common form of cancer in children. An international research consortium lead by pediatric oncologists from the Universities of Zurich and Hannover has now succeeded in decoding a specific form of this leukemia, which is regarded as incurable, and in obtaining insights for new therapeutic possibilities.

28 Jul 2015

Necrotising autoimmune myopathy requires early, aggressive treatment

Researchers call for the prompt recognition of necrotising autoimmune myopathy and aggressive early treatment with a combination of intravenous immune globulin, corticosteroids and a steroid-sparing agent for 3 months.

27 Jul 2015

Multiple sclerosis relapse management: an interview with Gina Remington

MS relapses are typically reflective of new neurological symptoms. However, it can be a worsening of neurologic symptoms that begins after a patient has been stable (generally for about 30 days), but relapses are persistent and consistent changes in symptoms that occur for more than 24 to 48 hours.

26 Jul 2015

Wayne State's faculty selected for Aspen Health Innovators Fellowship

The Washington, D.C.-based educational and policy studies organization The Aspen Institute has selected Wayne State University School of Medicine's Patrick Hines, M.D., Ph.D., associate professor of Physiology and an assistant professor of Pediatric Critical Care Medicine, one of only 20 health care leaders in the country for the inaugural class of its Health Innovators Fellowship.

25 Jul 2015

Trends, R&D progress, and predicted revenues in RNAi therapies

When will RNAi therapies reach the market? Visiongain's brand new report shows you potential revenues to 2025, assessing data, trends, opportunities and prospects there.

25 Jul 2015

Rutgers physicians use new treatments to restore teenager’s life

At first, 13-year-old Christina Blumstein thought she had an ordinary headache. She and her parents were returning from a visit to Long Island in July 2014 when the pain struck. Was it a bout of carsickness? Too much screen time on her iPad? But a few hours later, back home in Old Bridge, New Jersey, her mother MaryAnn says, "Christina started screaming that somebody was stabbing her in the head with a knife." Soon afterward Christina was comatose and in an ambulance - and her life was in grave danger.

25 Jul 2015

Prostate cancer patients more likely to receive medical care matched to level of risk

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

25 Jul 2015

NEJM suggests use of HCV-positive kidneys as one solution to kidney shortage

The average wait time for a kidney transplant is five years and there are more than 100,000 people on the waiting list. However, there are thousands of viable hepatitis C-positive kidneys that are discarded each year solely because they're infected.

25 Jul 2015

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Researchers from CalciMedica, Inc. and the University of Liverpool today announced the publication of a paper describing positive effects of calcium release-activated calcium (CRAC) channel inhibitors in animal models of acute pancreatitis. The paper, titled "Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models" appears in the August edition of the journal Gastroenterology.

25 Jul 2015

Novartis announces FDA approval of Odomzo (sonidegib) 200 mg capsules for treatment of laBCC patients

Novartis today announced the US Food and Drug Administration has approved Odomzo (sonidegib, formerly LDE225) 200 mg capsules for the treatment of adult patients with locally advanced basal cell carcinoma (laBCC) that has recurred following surgery or radiation therapy, or those who are not candidates for surgery or radiation therapy.

25 Jul 2015

Lupin signs strategic asset purchase agreement with Temmler

Pharma Major Lupin Limited today announced that it has entered into a strategic asset purchase agreement with TEMMLER PHARMA GMBH & CO. KG, a part of the Aenova Group, one of the world's largest pharmaceutical contract manufacturers, to acquire Temmler's specialty product portfolio subject to certain closing conditions.

25 Jul 2015

Therapy News and Research

Increased awareness of fertility preservation options needed for young patients with cancer

Innovative approach to treating AAT deficiency

Wayne State leads landmark study that examines clinical use of polymyxin B to treat superbugs

New technique improves survival time for glioblastoma patients by 50%

Protein imbalances within cells can cause ovarian cancer

Mobile Stroke Treatment Units can improve survival rates and enhance patient's chance of recovery

FDA grants Fast Track Designation to TxCell’s Ovasave for treatment of Crohn’s disease

GLP-2 therapy may help fight neonatal parenteral nutrition-associated liver disease

Landmark study to provide critical information for optimized use of polymyxin B in critically ill patients

Research sheds light on new therapeutic options for acute lymphoblastic leukemia

Necrotising autoimmune myopathy requires early, aggressive treatment

Multiple sclerosis relapse management: an interview with Gina Remington

Wayne State's faculty selected for Aspen Health Innovators Fellowship

Trends, R&D progress, and predicted revenues in RNAi therapies

Rutgers physicians use new treatments to restore teenager’s life

Prostate cancer patients more likely to receive medical care matched to level of risk

NEJM suggests use of HCV-positive kidneys as one solution to kidney shortage

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Novartis announces FDA approval of Odomzo (sonidegib) 200 mg capsules for treatment of laBCC patients

Lupin signs strategic asset purchase agreement with Temmler

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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