Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses like human immunodeficiency virus (HIV).

9 Dec 2021

Scientists determine structure of the molecule associated with ALS for the first time

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Research reveals a common cause for seizures and memory problems in epilepsy

Damage to a part of the brain that regulates hyperactivity can contribute to both memory problems and seizures in the most common form of epilepsy, according to research at the University of Wisconsin–Madison.

7 Dec 2021

New self-administered test can find the early subtle signs of dementia sooner

Many people experience forgetfulness as they age, but it's often difficult to tell if these memory issues are a normal part of aging or a sign of something more serious

7 Dec 2021

Study reveals the effects of cannabis use on oral microbiome and brain health

More and more states are legalizing marijuana, but little is known about how long-term cannabis use affects the microbes in the oral cavity, known as the oral microbiome.

6 Dec 2021

Researchers discover clearest evidence to date of how memories form

In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer's disease, and schizophrenia, UT Southwestern researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how memories are recalled in the brain.

6 Dec 2021

UC San Diego participates in the expansion of Parkinson’s Progression Markers Initiative

After a decade of pioneering research, the Parkinson's Progression Markers Initiative by The Michael J. Fox Foundation for Parkinson's Research will see a major expansion.

6 Dec 2021

Cataract surgery associated with lower risk of dementia

Cataracts affect most older adults at risk for dementia, and now researchers are finding strong evidence that cataract surgery is associated with a lower risk of developing dementia.

6 Dec 2021

Review: Diagnostic radiologists at higher risk of burnout

A review co-authored by Dr. Bradley Spieler, Vice-Chair of Scholarly Activity and Research in the Department of Radiology at LSU Health New Orleans School of Medicine, and Dr. Neil Baum, of Tulane's Department of Urology, reports that although burnout affects more than 50% of health care workers, diagnostic radiologists are at even higher risk.

4 Dec 2021

Elevated heart rate in old age may be an independent risk factor of dementia

Having an elevated resting heart rate in old age may be an independent risk factor of dementia, according to a study at Karolinska Institutet in Sweden published in the journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

3 Dec 2021

Cedars-Sinai researchers uncover the cause of UTI-induced delirium

Cedars-Sinai researchers have found that blocking the action of a protein called interleukin 6 (IL-6), part of the immune system, could resolve the delirium that often accompanies urinary tract infection (UTI) in elderly patients.

2 Dec 2021

Study could lead to new strategies to prevent or slow Alzheimer's disease

A gene mutation linked to Alzheimer's disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study by scientists at Weill Cornell Medicine.

1 Dec 2021

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

A human stroke drug, fast-tracked by the Food and Drug Administration and soon entering Phase 3 clinical trials, shows intriguing signs that it might also be a safe and powerful defense against Alzheimer's and other forms of dementia.

1 Dec 2021

For older adults, smelling the roses may be more difficult

The reports from covid-19 patients are disconcerting. Only a few hours before, they were enjoying a cup of pungent coffee or the fragrance of flowers in a garden. Then, as if a switch had been flipped, those smells disappeared.

1 Dec 2021

Study sheds light on Aβ deposition patterns in the brain from external sources

Alzheimer's disease (AD) involves the deposition of a protein called amyloid β protein (Aβ) in the brain. This protein can build up in both the functional tissues, or "parenchyma", of the brain, and in the blood vessels.

30 Nov 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

The proteins that belong to the HAT family are essential for life as they transport amino acids across the cell membrane. Although the members of this family are practically identical, some transport certain amino acids and not others.

29 Nov 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Brain scans of athletes exposed to repetitive head impacts show white matter hyperintensities

Certain markers of injury to the brain's white matter, called white matter hyperintensities, can be seen on brain scans.

25 Nov 2021

When the eye on older patients is a camera

In the middle of a rainy Michigan night, 88-year-old Dian Wurdock walked out the front door of her son's home in Grand Rapids, barefoot and coatless. Her destination was unknown even to herself.

23 Nov 2021

Alzheimer's Disease News and Research

Further Reading

Study reveals the role of intracellular receptor PQBP1 in response to Tau protein

Scientists determine structure of the molecule associated with ALS for the first time

Research reveals a common cause for seizures and memory problems in epilepsy

New self-administered test can find the early subtle signs of dementia sooner

Study reveals the effects of cannabis use on oral microbiome and brain health

Researchers discover clearest evidence to date of how memories form

UC San Diego participates in the expansion of Parkinson’s Progression Markers Initiative

Cataract surgery associated with lower risk of dementia

Review: Diagnostic radiologists at higher risk of burnout

Elevated heart rate in old age may be an independent risk factor of dementia

Cedars-Sinai researchers uncover the cause of UTI-induced delirium

Study could lead to new strategies to prevent or slow Alzheimer's disease

Fast-tracked human stroke drug may also be a safe and powerful defense against dementia

For older adults, smelling the roses may be more difficult

Study sheds light on Aβ deposition patterns in the brain from external sources

Potentially neurotoxic SARS-CoV-2 protein fragments

The mode of action of essential proteins involved in cancer and Alzheimer´s deciphered

Clinical drug research for the treatment of CNS and neurological disorders

Brain scans of athletes exposed to repetitive head impacts show white matter hyperintensities

When the eye on older patients is a camera

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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