Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine

The National Institutes of Health has awarded grants to researchers in the Perelman School of Medicine at the University of Pennsylvania to support "highly innovative and broadly impactful" biomedical science through the NIH Common Fund's High-Risk, High-Reward Research program. The seven awards total approximately $8.2 million over five years,

8 Oct 2021

Characterization of circulating neutrophils from hospitalized COVID-19 patients

A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with COVID-19.

8 Oct 2021

Chilblain-like lesions and COVID-19

The ongoing COVID-19 pandemic brought about by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been responsible for various cutaneous manifestations. Among them, chilblain-like lesions (CLL) have been found to occur more frequently.

7 Oct 2021

Mouse brain atlas may help understand the complex circuits of the human brain

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum of its innumerable parts.

7 Oct 2021

Neuroscientists unveil detailed atlas of brain cells

When you clicked to read this story, a band of cells across the top of your brain sent signals down your spine and out to your hand to tell the muscles in your index finger to press down with just the right amount of pressure to activate your mouse or track pad.

6 Oct 2021

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

The NIH Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.

6 Oct 2021

Gene expression changes during acute SARS-CoV-2 infection may decide long-COVID symptoms

A team of US-based scientists has recently revealed the changes in gene expression profiles associated with the long-term consequences of COVID-19.

6 Oct 2021

Study identifies specific small RNA molecule that can reduce levels of cancer-promoting gene

In a recent study published in CANCER RESEARCH , a team led by researchers at Tokyo Medical and Dental University (TMDU) identified a specific small RNA molecule, called a microRNA (miRNA or miR), that has the potential to be used as an anti-cancer therapeutic.

5 Oct 2021

A possible protective genetic polymorphism in COVID-19

A new study discusses the role of a mucin gene enhancer on the clinical phenotype of the COVID-19.

5 Oct 2021

Three U of U Health researchers win the 2021 NIH Director’s New Innovator Award

The National Institutes of Health has awarded grants to three University of Utah Health scientists through its competitive High-Risk, High-Reward Research (HRHR) program that funds highly innovative and unusually impactful biomedical or behavioral research proposed by extraordinarily creative scientists.

5 Oct 2021

New mathematical tool used to study the genetic interactions associated with cancer

Biologists at Cold Spring Harbor Laboratory are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems.

5 Oct 2021

Study reveals how the blood and immune systems develop in prenatal bone marrow

The first comprehensive analysis of how the blood and immune systems develop in prenatal bone marrow has been conducted by scientists at the Wellcome Sanger Institute, Newcastle University and their collaborators.

1 Oct 2021

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

A team of scientists from the USA and France has recently unveiled the mechanism of immune dysregulation in coronavirus disease 2019 (COVID-19) patients by analyzing the early-stage interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected epithelial cells and immune cells. The study is currently available on the bioRxiv* preprint server.

30 Sep 2021

Yale researchers uncover how the brain takes shape during mid-pregnancy

About four or five months after conception, a burst of synaptic growth begins in the prefrontal cortex (PFC) of the human fetus.

29 Sep 2021

Understanding noise-related hearing loss through changes in RNA levels

A growing number of people are suffering from hearing loss due to exposure to loud noises from heavy machinery, concerts, or explosions.

29 Sep 2021

Defect in the interferon system associated with more severe COVID-19

A component of the human interferon system that activates SARS-CoV-2 cellular defenses appears to be defective in a proportion of humans, new research reports. COVID-19 outcomes were more severe in hospitalized patients who exhibited this immune system deficit, the study shows.

29 Sep 2021

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Amyotrophic lateral sclerosis (ALS) is an intractable neurological disease. Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is a protein that tends to accumulate in increasing amounts, and the amount is strictly controlled by the splicing of TDP-43. Through cell experiments and analysis of human brain tissue, researchers at Brain Research Institute, Niigata University, led by Akihiro Sugai, M.D., Ph.D., have found that methylation of TDP-43 DNA is involved in the background of motor cortex involvement with aging in ALS

29 Sep 2021

Research finds increases in 'pandemic brain' after COVID-19 lockdowns

Chances are, the COVID-19 pandemic has affected your health — even if you have never been infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). According to new research from Harvard Medical School, the stress of isolation from lockdown and stay-at-home measures is making people sick.

29 Sep 2021

Researchers create an integrated pipeline for performing genetic screening studies

Today's genetic engineers have a plethora of resources at their disposal: an ever-increasing number of massive datasets available online, highly precise gene editing tools like CRISPR, and cheap gene sequencing methods. But the proliferation of new technologies has not come with a clear roadmap to help researchers figure out which genes to target, which tools to use, and how to interpret their results. So, a team of scientists and engineers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and the MIT Media Lab decided to make one.

28 Sep 2021

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

Machine learning can pinpoint "genes of importance" that help crops to grow with less fertilizer, according to a new study published in Nature Communications. It can also predict additional traits in plants and disease outcomes in animals, illustrating its applications beyond agriculture.

25 Sep 2021

Gene Expression News and Research

Further Reading

NIH awards more than $8 million to support seven high-risk, high-reward projects at Penn Medicine

Characterization of circulating neutrophils from hospitalized COVID-19 patients

Chilblain-like lesions and COVID-19

Mouse brain atlas may help understand the complex circuits of the human brain

Neuroscientists unveil detailed atlas of brain cells

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

Gene expression changes during acute SARS-CoV-2 infection may decide long-COVID symptoms

Study identifies specific small RNA molecule that can reduce levels of cancer-promoting gene

A possible protective genetic polymorphism in COVID-19

Three U of U Health researchers win the 2021 NIH Director’s New Innovator Award

New mathematical tool used to study the genetic interactions associated with cancer

Study reveals how the blood and immune systems develop in prenatal bone marrow

Early-stage interaction of monocytes with SARS-CoV-2-infected epithelial cell decides COVID-19 severity

Yale researchers uncover how the brain takes shape during mid-pregnancy

Understanding noise-related hearing loss through changes in RNA levels

Defect in the interferon system associated with more severe COVID-19

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Research finds increases in 'pandemic brain' after COVID-19 lockdowns

Researchers create an integrated pipeline for performing genetic screening studies

Machine learning pinpoints genes that enable plants to grow more with less fertilizer

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