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Stem cells used to create organoids that secrete dental enamel proteins

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

14 Aug 2023

Scientists identify key proteins driving cancer across multiple tumor types

Scientists have completed a deep analysis of the proteins driving cancer across multiple tumor types, information that can't be assessed by genome sequencing alone.

14 Aug 2023

New insights into severe obesity genetics: Evidence from adults seeking treatment reveals intriguing oligogenic patterns

Researchers explore the prevalence of rare genetic forms of obesity in a United Kingdom-based clinical obesity cohort.

14 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Study identifies 135 genes associated with human skin color

The skin, hair and eye color of more than eight billion humans is determined by the light-absorbing pigment known as melanin.

11 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

10 Aug 2023

Rice University chemist wins $1M NIH grant to address cancer health disparities

Rice University chemist Carolyn Nichol has won a competitive Science Education Partnership Award (SEPA) from the National Institutes of Health to address race-based cancer health disparities by increasing underrepresented minority student populations' engagement and participation in biosciences education.

10 Aug 2023

Study examines shared genetic etiology of chronic diseases and links leukocyte telomere length to heart failure risk

Researchers performed a prospective cohort study to investigate the shared genetic etiology between chronic diseases.

10 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Fruit fly study provides insights into piRNA production and fertility

You're likely familiar with RNA, the molecule that plays an important role in protein production and gene expression control.

9 Aug 2023

Deep-learning technology could help scientists to develop personalized immunotherapies and vaccines

Deep-learning technology developed by a team of Johns Hopkins engineers and cancer researchers can accurately predict cancer-related protein fragments that may trigger an immune system response.

9 Aug 2023

Ebola virus forms "viral factories" to replicate inside host cells

New research in the journal Nature Communications gives scientists an important window into how Ebola virus replicates inside host cells.

9 Aug 2023

Study reveals the genetics of hair whorl direction

The first gene mapping study on human scalp hair whorls not only shows that hair whorl direction has a genetic basis, but also that it is affected by multiple genes.

9 Aug 2023

ADHD diagnosis in childhood vs adulthood: is there a difference in genetic architecture?

Researchers investigated whether individuals diagnosed with ADHD during childhood vs adulthood differed in terms of unique and shared genetic and functional architectures.

9 Aug 2023

Effect of mutations in cancer-driving genes across human cancers

Effect of mutations in cancer-driving genes across human cancers.

9 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

Inflammation slows down the development of malaria parasites in bloodstream

Research led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and the Kirby Institute found that inflammation in the body can slow down the development of malaria parasites in the bloodstream – a discovery that may constitute a potential new strategy for preventing or limiting severe disease.

8 Aug 2023

Nationwide Children's Hospital pioneers new gene therapy for Duchenne muscular dystrophy

In a landmark moment for the Abigail Wexner Research Institute at Nationwide Children's, a 5-year-old from Bellefontaine, Ohio, received the first dose of a recently approved gene therapy for Duchenne muscular dystrophy at Nationwide Children's Hospital, where the therapy was invented and initially tested.

8 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

Genome News and Research

Stem cells used to create organoids that secrete dental enamel proteins

Scientists identify key proteins driving cancer across multiple tumor types

New insights into severe obesity genetics: Evidence from adults seeking treatment reveals intriguing oligogenic patterns

Exploring DNA methylation biomarkers of multiple sclerosis

Study identifies 135 genes associated with human skin color

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Rice University chemist wins $1M NIH grant to address cancer health disparities

Study examines shared genetic etiology of chronic diseases and links leukocyte telomere length to heart failure risk

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Fruit fly study provides insights into piRNA production and fertility

Deep-learning technology could help scientists to develop personalized immunotherapies and vaccines

Ebola virus forms "viral factories" to replicate inside host cells

Study reveals the genetics of hair whorl direction

ADHD diagnosis in childhood vs adulthood: is there a difference in genetic architecture?

Effect of mutations in cancer-driving genes across human cancers

The impact of epigenetic features on breast cancer treatment and outcomes

Inflammation slows down the development of malaria parasites in bloodstream

Nationwide Children's Hospital pioneers new gene therapy for Duchenne muscular dystrophy

Identification of plasma proteins associated with ovarian cancer risk

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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