Proliferation News and Research

RSS

Study identifies key role of TLK1 and TLK2 enzymes in DNA replication

During cell growth, cells copy their DNA through a process called DNA replication. For this process to be accurate, the genetic and epigenetic information must be copied flawlessly.

9 Aug 2018

Gene considered as tumor promoter may also halt development of cancer, shows study

A gene that has for decades been considered a tumor promoter, the PLK1 gene, can also perform the exact opposite function: halting the development of cancer.

9 Aug 2018

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

7 Aug 2018

Researchers reveal molecular mechanisms that make people with EV prone to ß-HPVs

Keratinocyte skin cells are common targets of the beta subtype of human papilloma virus. This usually harmless infection causes skin disease in people with rare gene mutations.

2 Aug 2018

Researchers discover key piece for slowing colorectal cancer subtype

Inhibiting the Jagged 1 protein in mice prevents the proliferation and growth of colon and rectal tumors. What is more, this approach to the disease permits the removal of existing tumors.

2 Aug 2018

Father’s genes can affect quality of maternal care received by a newborn

A father’s genes are no longer thought to just provide a blueprint for the growth and development of their offspring.

1 Aug 2018

Cancer cells proliferate less when their internal pH is lowered, study shows

A new computational model has allowed researchers to identify new therapeutic targets that can attack cancer cells by lowering their intracellular pH. The study, which is the result of collaboration between IRB Barcelona, the Moffitt Cancer Center, and the University of Maryland, has been published in Nature Communications.

31 Jul 2018

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended broadening the existing marketing authorization for Darzalex® for use as frontline therapy.

28 Jul 2018

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

Novartis today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending approval of Tafinlar® in combination with Mekinist® for the adjuvant treatment of adult patients with stage III melanoma with a BRAF V600 mutation, following complete resection.

27 Jul 2018

MicroRNA panel could categorize indeterminate thyroid nodule samples into malignant and benign

A panel of 19 microRNAs identified using next-generation sequencing could categorize indeterminate thyroid nodule samples into malignant and benign.

26 Jul 2018

New applications for high-throughput flow cytometry in drug discovery

A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry in drug discovery.

24 Jul 2018

Kite collaborates with Gadeta to develop novel gamma delta TCR therapies for various cancers

Kite, a Gilead Company, and Gadeta B.V., a privately-held company focused on the discovery and development of novel cancer immunotherapies based on gamma delta T cell receptors, have entered into a strategic collaboration to develop novel gamma delta TCR therapies in various cancers.

19 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018

Research uncovers new target for therapeutic intervention in breast cancer

Research led by Suresh Alahari, PhD, Professor of Biochemistry and Molecular Biology at LSU Health New Orleans School of Medicine, has shown for the first time that a tiny piece of RNA deregulates energy metabolism, an emerging hallmark of cancer. The finding identifies a new target for therapeutic intervention in breast cancer.

18 Jul 2018

Why men may recover more quickly from influenza infections than women

Men may recover more quickly from influenza infections because they produce more of a key lung-healing protein, a study from scientists at Johns Hopkins Bloomberg School of Public Health suggests.

17 Jul 2018

Inflection Biosciences' dual mechanism inhibitor shows promise as treatment for CLL

Inflection Biosciences Ltd, a private company developing innovative therapeutics for cancer, today announced the publication of preclinical data showing the company's dual mechanism PIM/PI3 kinase inhibitor IBL-202 has promise as a treatment for chronic lymphocytic leukemia.

17 Jul 2018

Proliferation News and Research

Study identifies key role of TLK1 and TLK2 enzymes in DNA replication

Gene considered as tumor promoter may also halt development of cancer, shows study

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Researchers reveal molecular mechanisms that make people with EV prone to ß-HPVs

Researchers discover key piece for slowing colorectal cancer subtype

Father’s genes can affect quality of maternal care received by a newborn

Cancer cells proliferate less when their internal pH is lowered, study shows

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

Novartis' new drug combination receives positive CHMP opinion for treating stage III BRAF mutant melanoma

MicroRNA panel could categorize indeterminate thyroid nodule samples into malignant and benign

New applications for high-throughput flow cytometry in drug discovery

Kite collaborates with Gadeta to develop novel gamma delta TCR therapies for various cancers

Study identifies RNA molecules that regulate male hormones in prostate cancer

Research uncovers new target for therapeutic intervention in breast cancer

Why men may recover more quickly from influenza infections than women

Inflection Biosciences' dual mechanism inhibitor shows promise as treatment for CLL

New molecule shows great promise for future treatment of many cancers

Fruit fly research leads to potential drug for debilitating diseases caused by parasitic worms

New approach sheds light on effects of drugs on cancer cells

Stem cell study brings scientists closer to understanding schistosomiasis

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News