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Cancer cells break down nerve covers causing immune exhaustion and therapy resistance

Cancer cells can break down the protective covers around nerves, causing nerve injury that triggers chronic inflammation leading to immune exhaustion and eventual resistance to immunotherapy, according to new research from The University of Texas MD Anderson Cancer Center.

20 Aug 2025

Fasting supports type 1 diabetes care by reshaping the microbiome

A week of fasting alters the gut microbiome in type 1 diabetes, aligning it with healthy profiles and enhancing cholesterol and weight management.

20 Aug 2025

Could chlorophyll become the next antidiabetic therapy?

Research highlights chlorophyll's role in blood sugar regulation and insulin mimicry, though safety risks and lack of human trials warrant caution.

20 Aug 2025

ChronODE method offers precision in timing gene therapy treatments

A Yale research team has created a new computer tool that can pinpoint when exactly genes turn on and off over time during brain development - a finding that may one day help doctors identify the optimal window to deploy gene therapy treatments.

20 Aug 2025

Radio waves offer new hope for improving sense of smell

Our sense of smell is more important than we often realize. It helps us enjoy food, detect danger like smoke or gas leaks, and even affects memory and emotion.

19 Aug 2025

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Texas Children's is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.

19 Aug 2025

FAST walk shows promise in improving gait for chronic stroke patients

Stroke remains one of the leading causes of long-term disability worldwide, affecting millions each year.

19 Aug 2025

Improving gene therapy safety with human kidney organoids

Ryuji Morizane, MD, PhD, of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new paper published in Signal Transduction and Targeted Therapy, "AAV for gene therapy drives a nephrotoxic response via NFκB in kidney organoids."

19 Aug 2025

Targeting the adrenomedullin pathway may be a potential therapy for liver failure

Liver failure syndromes are characterized by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) is a potent vasodilator and immunoregulator.

18 Aug 2025

Targeting a sugar metabolism pathway offers hope for treating rare and aggressive childhood cancer

A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to improved treatments for patients.

18 Aug 2025

Special robot hunts for the perfect cancer warriors

Cancer patients can regain full health with immunotherapy. Now researchers are hunting for the perfect immune cell with the help of a very special robot.

18 Aug 2025

Community-driven ADHD initiative leads to better outcomes for children

Innovative intervention delivered by trained community health workers – meaning nonclinical personnel with deep knowledge of the community – increased treatment utilization among participating families with children who have ADHD, according to a pilot study published in the Journal of Attention Disorders.

18 Aug 2025

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

The American Geriatrics Society (AGS) has released a landmark update to its list of alternatives to medications listed in the 2023 AGS Beers Criteria - the most widely adopted guidelines to help clinicians identify potentially inappropriate medications for older adults.

18 Aug 2025

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

18 Aug 2025

Therapy News and Research

Cancer cells break down nerve covers causing immune exhaustion and therapy resistance

Fasting supports type 1 diabetes care by reshaping the microbiome

Could chlorophyll become the next antidiabetic therapy?

ChronODE method offers precision in timing gene therapy treatments

Radio waves offer new hope for improving sense of smell

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

FAST walk shows promise in improving gait for chronic stroke patients

Improving gene therapy safety with human kidney organoids

Targeting the adrenomedullin pathway may be a potential therapy for liver failure

Targeting a sugar metabolism pathway offers hope for treating rare and aggressive childhood cancer

Special robot hunts for the perfect cancer warriors

Community-driven ADHD initiative leads to better outcomes for children

New update to the 2023 AGS Beers Criteria highlights safer pharmacologic options for older adults

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Inactivation of stress pathway allows ER+ breast cancer cells to evade treatment

Advancing cancer treatment with targeted microrobotic swarms

Exploring the complex origins of endothelial cells in tumor angiogenesis

Bacteria and viruses team up to target cancer

Health care groups aim to counter growing ‘national scandal’ of elder homelessness

ADHD medication lowers risk of substance misuse and accidents

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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